| The Michael J Fox Foundation for Parkinson's Research | $651,317,366 | 7 | 50% |
| University of California San Francisco Foundation | $168,078,721 | 5 | 12% |
| Climate Imperative Foundation | $129,001,648 | 3 | 19% |
| United States Energy Foundation | $60,505,895 | 2 | 12% |
| Lucile Packard Foundation for Children's Health | $33,745,467 | 2 | 25% |
| National Foundation for the Centers for Disease Control and Prevention Inc | $26,905,193 | 3 | 8% |
| Climateworks Foundation | $26,763,727 | 3 | 4% |
| The Broad Institute Inc | $17,500,387 | 1 | 2% |
| Multiplier | $15,543,648 | 3 | 13% |
| Blue Meridian Partners Inc | $15,024,273 | 2 | 5% |
| Tipping Point Community | $14,007,734 | 4 | 13% |
| La Jolla Institute for Immunology | $13,548,720 | 4 | 7% |
| The Aspen Institute Inc | $13,388,999 | 3 | 3% |
| Breakthrough Prize in Life Sciences Foundation | $12,602,938 | 5 | 23% |
| Resources Legacy Fund | $12,524,587 | 1 | 10% |
| California Institute of Technology | $12,272,049 | 3 | 0% |
| Rewiring America | $12,000,000 | 1 | 32% |
| Lifemoves | $11,348,927 | 3 | 12% |
| Aspen Global Change Institute Inc | $10,992,107 | 1 | 29% |
| Pacific Environment and Resources Center | $10,110,000 | 2 | 91% |
| Donorschooseorg | $9,505,433 | 5 | 2% |
| Rocky Mountain Institute | $9,415,001 | 5 | 3% |
| United Nations Foundation Inc | $9,381,349 | 3 | 4% |
| Cooperative for Assistance and Relief Everywhere Inc | $9,215,076 | 3 | 1% |
| University of Maryland College Park Foundation Inc | $8,750,000 | 6 | 1% |
| Elemental Excelerator Inc | $8,000,000 | 2 | 14% |
| Greenlight Fund Inc | $7,068,098 | 3 | 20% |
| C40 Cities Climate Leadership Group Inc | $7,050,884 | 2 | 8% |
| National Wildlife Federation | $6,622,606 | 2 | 3% |
| Earthjustice | $6,512,343 | 2 | 3% |
| Nueva School | $6,250,000 | 6 | 7% |
| Advanced Energy Institute | $6,027,360 | 2 | 41% |
| Calstart Inc | $5,350,000 | 2 | 1% |
| Second Harvest of Silicon Valley | $5,240,435 | 6 | 1% |
| Climate Jobs National Resource Center Inc | $5,100,000 | 2 | 21% |
| Target Als Foundation Inc | $5,004,210 | 1 | 10% |
| Mercy Corps | $5,003,272 | 1 | 1% |
| Save The Children Federation Inc | $5,002,956 | 1 | 0% |
| Ted Foundation Inc | $5,002,793 | 5 | 1% |
| Earth Fire Alliance | $5,000,000 | 1 | 21% |
| Healthcorps Inc | $5,000,000 | 1 | 77% |
| Buck Institute for Research on Aging | $4,925,898 | 4 | 4% |
| George Mason University Foundation Inc | $4,850,080 | 1 | 4% |
| Californians Dedicated to Education Foundation | $4,700,000 | 1 | 27% |
| Fresh Lifelines for Youth Inc | $4,570,000 | 4 | 19% |
| Time For Change Foundation | $4,000,000 | 3 | 32% |
| United Way of Summit and Medina | $3,300,191 | 4 | 5% |
| Trust for Hidden Villa | $3,240,000 | 5 | 31% |
| California Association of Food Banks | $3,218,000 | 7 | 1% |
| Homeless Prenatal Program Inc | $3,000,000 | 5 | 5% |
| Karuk Tribe | $3,000,000 | 1 | n/a |
| Saga Innovations Inc | $3,000,000 | 1 | 14% |
| Boys & Girls Clubs of the Peninsula | $2,624,206 | 2 | 5% |
| Alameda County Community Food Bank | $2,600,000 | 7 | 0% |
| The Board of Trustees of the University of Illinois | $2,547,554 | 1 | n/a |
| Green Hydrogen Coalition | $2,530,000 | 2 | 40% |
| International Medical Corps | $2,503,166 | 1 | 1% |
| International Rescue Committee INC | $2,503,166 | 1 | 0% |
| Urgent Action Fund for Feminist Activism | $2,501,636 | 1 | 13% |
| Hias Inc | $2,501,478 | 1 | 2% |
| Indiana University Foundation | $2,501,192 | 1 | 1% |
| US Association for International Migration | $2,500,000 | 1 | 55% |
| Epidaurus Dba Amity Foundation | $2,500,000 | 1 | 4% |
| The Millennium Promise Alliance Inc | $2,500,000 | 1 | 34% |
| United Ways of California | $2,450,000 | 4 | 10% |
| Climate Power Education Fund | $2,400,000 | 1 | 21% |
| Global Emergency Relief Recovery and Reconstruction | $2,270,000 | 3 | 40% |
| Mission Asset Fund | $2,250,000 | 5 | 6% |
| Natural Resources Defense Council Inc | $2,183,781 | 1 | 1% |
| Mercy Housing California | $2,100,000 | 1 | 3% |
| Human Rights First | $2,050,000 | 3 | 6% |
| Businesses United in Investing Lending & Development | $2,050,000 | 5 | 6% |
| Food Bank of Contra Costa and Solano | $2,040,000 | 7 | 0% |
| Alder Graduate School of Education | $2,000,528 | 3 | 7% |
| Goodpower Education Fund Inc | $2,000,432 | 1 | 12% |
| World Central Kitchen Inc | $2,000,019 | 4 | 0% |
| San Francisco Food Bank | $2,000,000 | 7 | 0% |
| Human Rights Foundation Inc | $2,000,000 | 4 | 3% |
| For Inspiration and Recognition of Science and Technology (FIRST) | $1,925,000 | 4 | 1% |
| Federation of American Scientists | $1,856,146 | 3 | 7% |
| Larkin Street Youth Services | $1,830,000 | 5 | 2% |
| Team Rubicon Inc | $1,800,000 | 2 | 2% |
| La Cocina | $1,705,000 | 6 | 6% |
| Leadingage Inc | $1,702,662 | 1 | 8% |
| Conservation International Foundation | $1,700,060 | 2 | 1% |
| Sol Relief | $1,675,000 | 2 | 81% |
| Breakthrough Energy Foundation | $1,600,101 | 1 | 1% |
| CarbonPlan | $1,575,000 | 3 | 20% |
| Buckminster Fuller Institute | $1,565,513 | 1 | 53% |
| Beyond 12 Education Inc | $1,525,000 | 5 | 10% |
| The Jeremy and Hannelore Grantham Environmental Trust | $1,500,887 | 1 | 2% |
| League of Conservation Voters Education Fund | $1,500,279 | 1 | 2% |
| Airbnborg Inc | $1,500,000 | 2 | 1% |
| Western Reserve Community Fund Inc | $1,500,000 | 2 | 30% |
| Project Drawdown | $1,500,000 | 1 | 18% |
| Environmental Defense Fund Incorporated | $1,494,727 | 1 | 1% |
| Partnership for Public Service Inc | $1,403,260 | 1 | 7% |
| Edward Charles Foundation | $1,350,000 | 2 | 2% |
| Management Leadership for Tomorrow | $1,300,176 | 3 | 3% |
| National Center for Civic Innovation In | $1,267,015 | 1 | 5% |
| Swords to Plowshares Veterans Rights Organization | $1,250,000 | 4 | 2% |
| Braven Inc | $1,250,000 | 4 | 2% |
| First Place for Youth | $1,250,000 | 5 | 1% |
| Audubon Canyon Ranch Inc | $1,226,904 | 1 | 25% |
| Preble Street | $1,203,635 | 1 | 5% |
| Interstate Renewable Energy Council | $1,200,340 | 1 | 13% |
| Solar United Neighbors Inc | $1,200,000 | 1 | 9% |
| Nova Ukraine | $1,200,000 | 1 | 2% |
| Measures for Justice Institute | $1,200,000 | 4 | 7% |
| Harlem Children's Zone Inc | $1,125,033 | 5 | 1% |
| The Anti-Recidivism Coalition | $1,110,694 | 2 | 12% |
| National League of Cities Institute Inc | $1,087,500 | 1 | 4% |
| Durant Family Charitable Foundation | $1,035,000 | 2 | 32% |
| Boys & Girls Clubs of San Francisco | $1,025,000 | 4 | 2% |
| United Way of Northern California | $1,002,569 | 1 | 24% |
| Amici Lovanienses Inc | $1,002,246 | 1 | 59% |
| Borealis Philanthropy | $1,000,528 | 1 | 2% |
| Sherwood Forestry Service | $1,000,000 | 1 | 21% |
| Meals on Wheels California Inc | $1,000,000 | 2 | 97% |
| Cultural Fire Management Council | $1,000,000 | 1 | 40% |
| Public Health Institute | $1,000,000 | 1 | 0% |
| Grantmakers Concerned With Immigrants and Refugees | $1,000,000 | 1 | 9% |
| Givedirectly Inc | $1,000,000 | 1 | 0% |
| The Sunrise Project Inc | $1,000,000 | 1 | 2% |
| Cold Spring Harbor Laboratory | $1,000,000 | 1 | 0% |
| Cal Poly Humboldt Sponsored Programs Foundation | $952,000 | 2 | 1% |
| Building Opp for Self-Sufficiency | $925,000 | 4 | 2% |
| Inova Health Care Services | $900,275 | 1 | 0% |
| Caminar | $900,000 | 3 | 1% |
| West Oakland Job Resourse Center | $900,000 | 3 | 44% |
| Rush University Medical Center | $892,359 | 1 | 0% |
| Children's Health Council Inc | $812,500 | 4 | 1% |
| Council for Native Hawaiian Advancement | $800,000 | 1 | 2% |
| University of Utah | $800,000 | 1 | n/a |
| New Door Ventures Fka Golden Gate Community Inc | $775,000 | 5 | 4% |
| Jewish Vocational & Career Counseling Service | $770,000 | 4 | 2% |
| Sierra Health Foundation Center for Health Program Management | $750,000 | 1 | 0% |
| The International Council on Clean Transportation Inc | $750,000 | 1 | 3% |
| Fisher House Foundation Inc | $750,000 | 4 | 0% |
| Baylor College of Medicine | $705,000 | 2 | 0% |
| Fii - National | $700,000 | 4 | 1% |
| Prospera Community Development | $650,000 | 4 | 18% |
| Yachtaid Global | $649,400 | 3 | 75% |
| Direct Relief | $647,000 | 2 | 0% |
| Semper Fi & America's Fund | $640,000 | 4 | 0% |
| Safe & Sound | $600,000 | 5 | 1% |
| Jobtrain Inc | $580,000 | 5 | 2% |
| Law Enforcement Action Partnership Inc | $550,000 | 2 | 30% |
| Give Foundation Inc | $550,000 | 1 | 1% |
| Southside Family Nurturing Center | $520,000 | 1 | 29% |
| Meals on Wheels of San Francisco Inc | $500,000 | 1 | 2% |
| California Fire Foundation | $500,000 | 1 | 4% |
| Spark Program Inc | $500,000 | 2 | 14% |
| Center for Planning Excellence | $500,000 | 1 | 19% |
| Healthy Brains Global Initiative Inc | $500,000 | 1 | n/a |
| The American Himalayan Foundation | $500,000 | 1 | 12% |
| Profectum Foundation | $500,000 | 1 | 51% |
| Benevolent Healthcare Foundation | $500,000 | 1 | 1% |
| Sesame Workshop | $500,000 | 1 | 0% |
| Cal Poly Humboldt Foundation | $500,000 | 1 | 3% |
| Act Now Coalition | $500,000 | 1 | 32% |
| Statue of Liberty Ellis Island Foundation Inc | $500,000 | 1 | 3% |
| Policing Equity | $500,000 | 1 | 1% |
| COOP Careers Inc | $487,500 | 4 | 2% |
| President-Board of Trustees Santa Clara College | $474,000 | 1 | 0% |
| Doctors for You - USA Inc | $450,000 | 1 | 48% |
| Full Circle Fund | $430,000 | 3 | 18% |
| The Milken Institute | $425,000 | 1 | 1% |
| Parkinson's Institute and Clinical Center | $410,000 | 1 | n/a |
| Mary's Center for Maternal and Child Care Inc | $400,000 | 1 | 1% |
| Casa Inc | $400,000 | 1 | 2% |
| Color of Changeorg Education Fund | $400,000 | 2 | 3% |
| Citizen Schools Inc | $400,000 | 2 | 2% |
| Partnership With Native Americans | $400,000 | 1 | 1% |
| Reading Partners | $400,000 | 2 | 1% |
| Ravenswood Education Foundation | $400,000 | 2 | 2% |
| Head Strong Project Inc | $390,000 | 4 | 2% |
| Panorama Global | $385,000 | 1 | 1% |
| Life Learning Academy | $370,000 | 5 | 2% |
| Northwest Immigrant Rights Project | $350,000 | 2 | 2% |
| Voice of the Experienced Vote | $350,000 | 1 | 34% |
| Gridworks Organization | $350,000 | 1 | 14% |
| Talkingpoints | $325,000 | 1 | 5% |
| People's Action Institute | $325,000 | 1 | 4% |
| Imentor Inc | $312,500 | 2 | 1% |
| Redwood Empire Food Bank | $305,000 | 3 | 0% |
| National Institute for Criminal Justice Reform | $300,000 | 2 | 24% |
| Bullis-Purissima Elementary School Foundation | $300,000 | 1 | 7% |
| Stark State College Foundation | $300,000 | 1 | 10% |
| K to College Dba Supplybankorg | $300,000 | 1 | 5% |
| Puente de la Costa Sur | $300,000 | 1 | 4% |
| Second Harvest of the Greater Valley | $285,000 | 3 | 0% |
| National Fallen Firefighters Foundation | $280,000 | 4 | 1% |
| Concerns of Police Survivors Inc | $280,000 | 4 | 2% |
| One Life Counseling Center | $275,000 | 1 | 4% |
| Ukraine Defense Fund Inc | $275,000 | 1 | 3% |
| Vera Institute of Justice Inc | $250,000 | 1 | 0% |
| Genesys Works | $250,000 | 1 | n/a |
| Second Harvest Food Bank Santa Cruz County | $250,000 | 3 | 1% |
| Peer Health Exchange Inc | $250,000 | 1 | 5% |
| Muralism | $250,000 | 1 | 58% |
| Playworks Education Energized | $250,000 | 2 | 1% |
| College Track | $250,000 | 1 | 1% |
| Fountain House Inc | $250,000 | 1 | 1% |
| Impact Justice | $250,000 | 1 | 2% |
| Syrian American Medical Society Foundation | $250,000 | 1 | 0% |
| Children of Fallen Patriots Foundation | $250,000 | 1 | 2% |
| NAACP Empowerment Programs Inc | $250,000 | 1 | 0% |
| Essie Justice Group | $250,000 | 1 | 12% |
| Summer Search | $250,000 | 2 | 1% |
| The Tech Interactive | $250,000 | 1 | 1% |
| Ella Baker Center for Human Rights | $250,000 | 1 | 4% |
| Yolo Food Bank | $240,000 | 2 | 1% |
| International Wilderness Leadership Foundation Inc | $231,000 | 1 | 4% |
| Burning Man Project | $230,000 | 1 | 0% |
| The George Washington University | $215,676 | 1 | 0% |
| The Mission Continues | $200,000 | 1 | 2% |
| Faith in Texas - Pico | $200,000 | 1 | 17% |
| Nus America Foundation Inc | $200,000 | 1 | 9% |
| GridLab Inc | $200,000 | 1 | 3% |
| Catholic Charities of the Diocese of Santa Rosa | $200,000 | 1 | 1% |
| Help a Mother Out | $200,000 | 1 | 7% |
| Medical Debt Resolution Inc | $200,000 | 1 | 0% |
| Foundation for the National Institutes of Health Inc | $200,000 | 1 | 0% |
| Minds Matter of Bay Area Inc | $200,000 | 1 | 20% |
| Hire Heroes USA Inc | $200,000 | 1 | 1% |
| The Call of Duty Endowment | $200,000 | 1 | 2% |
| Capital Area Food Bank Inc | $200,000 | 1 | 0% |
| Foundation for California Community Colleges | $200,000 | 1 | 0% |
| Tax-Aid | $200,000 | 4 | 23% |
| La Clinica del Pueblo Inc | $200,000 | 1 | 1% |
| Community Legal Services in East Palo Alto Inc | $200,000 | 1 | 3% |
| Gary Sinise Foundation | $200,000 | 1 | 0% |
| Minds Matter of Cleveland Ohio Inc | $195,000 | 1 | 37% |
| PowerMyLearning Inc | $190,000 | 2 | 1% |
| Project Tf | $190,000 | 2 | 3% |
| Eastside College Preparatory School Inc | $181,250 | 2 | 1% |
| Gillette Children's Hospital Foundation | $180,000 | 1 | 1% |
| The Brian Grant Foundation | $175,000 | 2 | 22% |
| American Lung Association | $175,000 | 1 | 0% |
| Year Up Inc | $175,000 | 2 | 0% |
| Progressnow Colorado Education | $170,000 | 1 | 12% |
| Girls Who Code Inc | $160,000 | 2 | 1% |
| United Way of Santa Barbara County Inc | $150,000 | 1 | 3% |
| Purpose Dignity Action | $150,000 | 1 | 1% |
| United Help Ukraine Inc | $150,000 | 1 | 0% |
| The Black Organizing Project Inc | $150,000 | 1 | 6% |
| Regents of the University of Michigan | $149,313 | 1 | n/a |
| Navigator Labs Fka Gooru | $145,000 | 2 | 5% |
| Thearte You Inc | $135,000 | 3 | 23% |
| The Commit Foundation | $130,000 | 1 | 3% |
| The Sand County Foundation Inc | $120,000 | 1 | 2% |
| Hispanic Federation Inc | $120,000 | 1 | 0% |
| Tomkat Ranch Educational Foundation | $119,625 | 1 | 3% |
| Americans for Oxford Inc | $101,800 | 1 | 0% |
| San Jose Grail Family Services | $100,000 | 1 | 4% |
| The Friends of the Oakland Public Library | $100,000 | 1 | n/a |
| Lifespan Research Institution | $100,000 | 1 | 4% |
| Stanford Health Care | $100,000 | 1 | 0% |
| Smartmeme DBA Center for Story-based Strategy | $100,000 | 1 | 10% |
| Cedars-Sinai Medical Center | $100,000 | 1 | 0% |
| Robot Heart Foundation Inc | $100,000 | 1 | 4% |
| Center for Empowered Politics Education Fund | $100,000 | 1 | 1% |
| NAACP Foundation | $100,000 | 2 | 8% |
| Helping Educate to Advance the Rights of the Deaf | $100,000 | 1 | 19% |
| Researchamerica | $100,000 | 1 | 1% |
| Excellence in Education Foundation for Pgcps Inc | $100,000 | 1 | 19% |
| Akron Community Service Center & Urban League Inc | $100,000 | 1 | 2% |
| Roses in Concrete | $80,000 | 1 | 1% |
| Allen Institute | $80,000 | 1 | 0% |
| Step Up Women's Network | $80,000 | 2 | 1% |
| Bellwether Education Partners Inc | $75,300 | 1 | 0% |
| Girls Leadership Institute Inc dba Girls Leadership | $70,000 | 2 | 2% |
| StarVista | $62,500 | 2 | 0% |
| Point Reyes Bird Observatory | $61,726 | 1 | 0% |
| Gate to Ukraine Inc | $53,700 | 1 | 22% |
| Ignite | $50,000 | 2 | 2% |
| The One Love Foundation in Honor of Yeardley Love Inc | $50,000 | 1 | 1% |
| La Raza Services Inc | $50,000 | 1 | 2% |
| Mission of Love Charities Inc | $50,000 | 1 | 4% |
| Technovation | $50,000 | 2 | 1% |
| The American Society for the Prevention of Cruelty to Animals | $50,000 | 1 | 0% |
| Jews for Racial & Economic Justice | $50,000 | 1 | 3% |
| Pursuit Of Excellence | $50,000 | 2 | 3% |
| Peninsula Youth Theatre | $50,000 | 1 | 4% |
| 826 Valencia | $50,000 | 1 | 1% |
| Project Giving Kids | $50,000 | 1 | 24% |
| United Way Inc | $50,000 | 1 | 1% |
| Communities United Against Police Brutality | $50,000 | 1 | 3% |
| Revived Soldiers Ukraine | $50,000 | 1 | 0% |
| Blood Cancer United Inc | $50,000 | 1 | 0% |
| Regents of the University of California | $50,000 | 1 | n/a |
| Franklin Center | $40,000 | 1 | 0% |
| The A21 Campaign Inc | $39,000 | 1 | 0% |
| Prince George's County Memorial Library System | $37,000 | 1 | 0% |
| Sustainable Markets Foundation | $30,000 | 1 | 0% |
| Takeaction Mn Education Fund | $25,000 | 1 | 0% |
| Software Freedom Conservancy Inc | $20,000 | 1 | n/a |
| Mary House Inc | $20,000 | 1 | 3% |
| National Girls Collaborative | $20,000 | 1 | n/a |
| Victim Assistance Program Inc | $15,000 | 1 | 1% |
| Hope and Healing Survivor Resource Center | $15,000 | 1 | 0% |
| Witness Inc | $10,000 | 1 | 0% |
| Community Initiatives | $7,000 | 1 | 0% |