Massachusetts · Nonprofit
ALZHEIMER'S DISEASE RESEARCH FOUNDATION
ALZHEIMER'S DISEASE RESEARCH FOUNDATION (Massachusetts) receives grants from 605 organizations whose IRS filings report $85,469,068 to it, the largest being FIDELITY INVESTMENTS CHARITABLE GIFT FUND ($14,699,790). 358 of them have funded it in more than one year, and 51% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
- Revenue FY2025
- $57M
- Funders on record
- 605
- Grants received
- $85M
- Net assets
- $37M
What Alzheimer's Disease Research Foundation does
Mission
To fund research with the highest probability of preventing, slowing or reversing alzheimer's disease. All overhead expenses are paid by the board of directors, trustees and core group of other donors, allowing 100% of general donations to fund our research programs.
As stated on its FY2025 Form 990.
Programs
In 2025, cure alzheimer's fund supported 161 research projects at 74 leading research institutions, for a total research output of $38.3 million. Projects identified and investigated mechanisms of action of the genes and variants with the biggest impact on risk and timing of alzheimer's disease as potential therapeutic targets. Other standalone projects and multi-lab consortia pursued novel theories and tools to assess potential avenues for prevention and treatment, in particular regarding the role of neuroinflammation, the gut microbiome, and the immune system in healthy brain function. Curealz also provided funding to sustain vital research assets, like brain banks and scientific trainees, facing unanticipated reductions in federal support. Additional expenses include scientific meeting hosting; husbandry of transgenic animal models by a contract research organization; the direct support of facilitating grants and the award process; and costs associated with assessing research proposals and determining funding priorities.
$38,338,893 spentof which $37,323,497 as grants90% of program spendingCreating awareness took the form of mailings, outreach, webinars, and support of third party events designed to raise awareness about the need for more research into the origins and progression of alzheimer's disease.
$4,220,285 spent10% of program spending
The 2 programs described on its FY2025 Form 990, listed largest first by expense. Program spending in total: $42,559,178.
The organization over time
Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.
Balance sheet
Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2024 to 2025, from $29M to $43M (+51%).
How it's funded, over time
Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.
98% of ALZHEIMER'S DISEASE RESEARCH FOUNDATION’s revenue is contributions — more reliant on donations than three-quarters of its peers (7% for the typical peer).
Surplus & reserves
Operating surplus or deficit each year, and months of liquidity in hand. 3 of the last 9 reported years ran a deficit.
reserve
Leadership and staff
The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.
Chief executive
Margaret E Smith
CEO & director
Board chair
Henry Mccance
Chair & director
As listed on its FY2025 Form 990.
The chief executive listed changed between the FY2022 and FY2023 filings.
Who funds it, year by year
2017 → 2023: the base broadened from 145 funders to 244 funders, grant income rose $5.0M → $14M.
82 of 605 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 51% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.
From the IRS filings of ALZHEIMER'S DISEASE RESEARCH FOUNDATION’s funders (the co-funder graph). Top 30 of 605 funders by total. Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How concentrated its funding is
ALZHEIMER'S DISEASE RESEARCH FOUNDATION has a broad base — no single funder exceeds 17% of grant income, and it takes 10 funders to reach half.
the vertical line marks half of all grant income — 10 funders to its left
55% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund ALZHEIMER'S DISEASE RESEARCH FOUNDATION.
Largest funder’s share by year: 2017 20% · 2018 18% · 2019 15% · 2020 20% · 2021 12% · 2022 23% · 2023 17% — diversifying over time.
“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How long its funders stay
45% of ALZHEIMER'S DISEASE RESEARCH FOUNDATION's funders are still giving 3 years after their first grant; 59% give in more than one year at all.
Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.
Where its funders are
51% of ALZHEIMER'S DISEASE RESEARCH FOUNDATION's grant income arrives through donor-advised or pass-through sponsors, whose addresses record where the money is held rather than where the donor is. Of the $42M that is directly attributable, 83% of it comes from funders outside Massachusetts, across 42 states.
In-state vs out-of-state, by year
Funder states come from each funder’s own filing. $44M arriving through sponsors registered in 30 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Against its field
ALZHEIMER'S DISEASE RESEARCH FOUNDATION runs a healthier operating margin than three-quarters of the 2,969 health nonprofits its size.
this organization peer median middle 50% of peers· 2,969 health nonprofits $10M–$100M, FY2025
Organizations like ALZHEIMER'S DISEASE RESEARCH FOUNDATION
Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.
In Massachusetts
Nationally
Read directly from this organization’s own Form 990, as neutral context.
Where the money goes
92% of spending goes to programs.
Governance
Public support
90%
Share of support from the public (Schedule A) — the basis for its public-charity status.
Footprint & structure
Files a return copy in 1 state
Screen this organization
A dated, signed PDF of the compliance screen for ALZHEIMER'S DISEASE RESEARCH FOUNDATION: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.
Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf
Questions and answers
- Who funds ALZHEIMER'S DISEASE RESEARCH FOUNDATION?
- ALZHEIMER'S DISEASE RESEARCH FOUNDATION (Massachusetts) receives grants from 605 organizations whose IRS filings report $85,469,068 to it, the largest being FIDELITY INVESTMENTS CHARITABLE GIFT FUND ($14,699,790). 358 of them have funded it in more than one year, and 51% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
- How many funders does ALZHEIMER'S DISEASE RESEARCH FOUNDATION have?
- IRS filings report 605 organizations giving $85,469,068 in grants to ALZHEIMER'S DISEASE RESEARCH FOUNDATION, 358 of which have funded it in more than one year.
- Who is the largest funder of ALZHEIMER'S DISEASE RESEARCH FOUNDATION?
- FIDELITY INVESTMENTS CHARITABLE GIFT FUND is the largest funder on record, with $14,699,790 in grants. The full list of funders is on this page.
- How can an organization like ALZHEIMER'S DISEASE RESEARCH FOUNDATION find more funders?
- Start with the funders already giving here, then look at the foundations that back similar organizations in Massachusetts. The funding by cause and by state pages list the largest funders for a given area and how to approach them.
These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2017–2025), and the filings of 605 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 22, 2026. What this page cannot tell you · view filing