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Texas · Nonprofit

SLC6A1 CONNECT

SLC6A1 CONNECT (Texas) receives grants from 38 organizations whose IRS filings report $2,139,161 to it, the largest being PAYPAL CHARITABLE GIVING FUND ($637,978). 18 of them have funded it in more than one year, and 71% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.

Revenue FY2024
$717k
Funders on record
38
Grants received
$2.1M
Net assets
$2.1M
18/38 repeat funderspeak grant-dependency 45%
01What it does

What Slc6a1 Connect does

Mission

Slc6a1 Connect is a patient advocacy group dedicated to improving the lives of children and families affected by the slc6a1 mutation. Our focus is to raise awareness and fundraising to advance scientific research that will ultimately result in a cure.

As stated on its FY2024 Form 990.

Programs

  1. Slc6a1 Connect supports targeted research and provides funding to research institutions to quickly advance the development of treatments and ultimately a cure for slc6a1.

    $447,998 spentof which $266,446 as grants
    75% of program spending
  2. Slc6a1 Connect carried out an international scientific symposium and family conference in december 2024. The international scientific symposium includes a full day of clinical updates, scientific presentations and protocols, the latest research, family testimonials and an engaging panel discussion on clinical trial readiness.

    $152,085 spent$65,834 earned by the program
    25% of program spending

The 2 programs described on its FY2024 Form 990, listed largest first by expense. Program spending in total: $600,083.

02The organization over time

The organization over time

Each line starts at 100 in 2019, so what you read is the shape rather than the size: 150 means half as much again as 2019, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20192019 Revenue 100 ($2.2M) Expenses 100 ($72k) Net assets 100 ($2.2M)2020 Revenue 37 ($801k) Expenses 998 ($714k) Net assets 99 ($2.2M)2021 Revenue 45 ($984k) Expenses 675 ($483k) Net assets 122 ($2.7M)2022 Revenue 43 ($945k) Expenses 1337 ($957k) Net assets 123 ($2.7M)2023 Revenue 31 ($677k) Expenses 1767 ($1.3M) Net assets 96 ($2.1M)2024 Revenue 33 ($717k) Expenses 949 ($680k) Net assets 98 ($2.1M)
201920202021202220232024
Revenue (33)Expenses (949)Net assets (98)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2020 to 2021, from $2.2M to $2.8M (+26%).

$2.2M
$2.2M
$2.8M
$2.8M
$2.3M
$2.4M
201920202021202220232024
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2019
2020
2021
2022
2023
2024
ContributionsProgram revenueInvestmentOther

78% of SLC6A1 CONNECT’s revenue is contributions — about as donation-reliant as the typical peer (82% for the typical peer).

This organization
Typical peer · 14,893 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 2 of the last 6 reported years ran a deficit.

$2.1M
’19
$87k
’20
$501k
’21
−$12k
’22
−$588k
’23
$37k
’24
4.8
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Chief executive

Amber Freed

Founder/CEO

Board chair

Gretchen Mcalister

Fundraising co-chair

As listed on its FY2024 Form 990.

201920202021202220232024
Listed568888
Joined·+2+6+2+2+1
No longer listed·14221
03Who funds it

Who funds it, year by year

2018 → 2023: the base broadened from 1 funder to 11 funders, grant income rose $60k → $135k.

14 of 38 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 71% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

From the IRS filings of SLC6A1 CONNECT’s funders (the co-funder graph). Top 30 of 38 funders by total. Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

SLC6A1 CONNECT leans on a few funders — its largest provides 30% of grant income and the top three 63%; half comes from just 2 funders.

the vertical line marks half of all grant income — 2 funders to its left

71% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund SLC6A1 CONNECT.

30%
largest funder
63%
top three
~6
effective funders

Largest funder’s share by year: 2018 100% · 2019 51% · 2020 40% · 2021 36% · 2022 49% · 2023 51% — diversifying over time.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How long its funders stay

33% of SLC6A1 CONNECT's funders are still giving 3 years after their first grant; 47% give in more than one year at all.

first grant+1y+2y+3y+4y

Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.

Where its funders are

71% of SLC6A1 CONNECT's grant income arrives through donor-advised or pass-through sponsors, whose addresses record where the money is held rather than where the donor is. Of the $610k that is directly attributable, 100% of it comes from funders outside Texas, across 16 states.

MN
IL
NY
IA
IN
PA
NJ
CA
CO
MO
DE
KS
NC
DC
TX
FL

In-state vs out-of-state, by year

’19
’20
’21
’22
’23
Texas out of state home

Funder states come from each funder’s own filing. $1.5M arriving through sponsors registered in 13 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

SLC6A1 CONNECT runs a healthier operating margin than half of the 13,754 health nonprofits its size.

Operating margin5% · above the median
Months of reserve4.8mo · below the median
Revenue growth (annualized)−20% · bottom quartile

this organization peer median middle 50% of peers· 13,754 health nonprofits $100k–$1M, FY2024

Organizations like SLC6A1 CONNECT

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In Texas

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

88% of spending goes to programs.

Program 88%Management 4%Fundraising 8%

Governance

8
board members
88%
independent
–Conflict-of-interest policy–Whistleblower policy–Document retention✓Board reviewed the 990–Audited financials

Public support

96%

Share of support from the public (Schedule A) — the basis for its public-charity status.

Screen this organization

A dated, signed PDF of the compliance screen for SLC6A1 CONNECT: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds SLC6A1 CONNECT?
SLC6A1 CONNECT (Texas) receives grants from 38 organizations whose IRS filings report $2,139,161 to it, the largest being PAYPAL CHARITABLE GIVING FUND ($637,978). 18 of them have funded it in more than one year, and 71% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
How many funders does SLC6A1 CONNECT have?
IRS filings report 38 organizations giving $2,139,161 in grants to SLC6A1 CONNECT, 18 of which have funded it in more than one year.
Who is the largest funder of SLC6A1 CONNECT?
PAYPAL CHARITABLE GIVING FUND is the largest funder on record, with $637,978 in grants. The full list of funders is on this page.
How can an organization like SLC6A1 CONNECT find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in Texas. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2024 (financials across 2019–2024), and the filings of 38 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing