Texas · Nonprofit
FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS
FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS (Texas) receives grants from 65 organizations whose IRS filings report $7,300,238 to it, the largest being THE MARNIER-LAPOSTOLLE FOUNDATION ($4,156,205). 33 of them have funded it in more than one year.
- Revenue FY2024
- $5.4M
- Funders on record
- 65
- Grants received
- $7.3M
- Net assets
- $40M
What Foundation for Angelman Syndrome Therapeutics does
Mission
Angelman syndrome (as) is a neurodevelopmental disorder characterized by global development delays and severe speech impairment. A few individuals with as develop functional speech, but most communicate through a mixture of gestures, eye gaze, adapted sign language and augumentative communication devices. Individuals with as have development delay and intellectual disabilities. Current research suggests that neuronal development occurs correctly in as, but neuronal functioning is impaired. This neuronal impairment impacts the individual's ability to learn in that skills are acquired less rapidly than in age-matched peers. The Foundation for Angelman Syndrome Therapeutics is an organization of families and professionals dedicated to finding a cure for as and related disorders through the funding of an agressive research agenda, education, advocacy, and community support. Fast is committed to assisting individuals living with as to realize their full potential and quality of life.
As stated on its FY2024 Form 990.
Programs
Fast's primary goal is to advance research leading to a cure for as in the form of providing grants to universities to perform research and testing.
$3,698,573 spentof which $3,698,573 as grants40% of program spendingAs is a rare disorder. The community of parents and caregivers of individuals with as rely heavily on social networking to become informed and seek advice and guidance on the challenges which the disorder presents. It is one of fast's objectives to educate, support, and strengthen this community.
$5,532,984 spent60% of program spending
The 2 programs described on its FY2024 Form 990, listed largest first by expense. Program spending in total: $9,231,557.
The organization over time
Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.
Balance sheet
Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2021 to 2022, from $18M to $63M (+255%).
How it's funded, over time
Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.
Government-grant reliance: 2021 1%. Grants only. Government contracts and fees sit inside program revenue.
69% of FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS’s revenue is contributions — more donation-reliant than the typical peer (51% for the typical peer).
Surplus & reserves
Operating surplus or deficit each year, and months of liquidity in hand. 3 of the last 8 reported years ran a deficit.
reserve
Leadership and staff
The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.
Chief executive
Alana Newhouse
President/CEO
Board chair
Ryan Jacob
Chairperson
As listed on its FY2024 Form 990.
Who funds it, year by year
2017 → 2023: the base broadened from 11 funders to 19 funders, grant income fell $4.5M → $344k.
24 of 65 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 35% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.
From the IRS filings of FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS’s funders (the co-funder graph). Top 30 of 65 funders by total. Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How concentrated its funding is
FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS leans on a few funders — its largest provides 57% of grant income and the top three 70%; half comes from just 1 funder.
the vertical line marks half of all grant income — 1 funder to its left
38% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS.
Largest funder’s share by year: 2017 93% · 2018 26% · 2019 29% · 2020 16% · 2021 34% · 2022 22% · 2023 27% — diversifying over time.
“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How long its funders stay
33% of FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS's funders are still giving 3 years after their first grant; 51% give in more than one year at all.
Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.
Where its funders are
FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS draws 99% of its grant income from funders outside Texas, across 21 states in all.
In-state vs out-of-state, by year
Funder states come from each funder’s own filing. $2.6M arriving through sponsors registered in 18 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Against its field
FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS's revenue fell 38% between 2017 and 2024.
this organization peer median middle 50% of peers· 8,126 health nonprofits $1M–$10M, FY2024
Organizations like FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS
Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.
In Texas
Nationally
Read directly from this organization’s own Form 990, as neutral context.
Where the money goes
89% of spending goes to programs.
Governance
Public support
67%
Share of support from the public (Schedule A) — the basis for its public-charity status.
Footprint & structure
Files a return copy in 34 states
Part of a family of 3 related entities
- Transformatx Biotherapeutics LLC · partnership
- Mavrix Bio LLC · partnership
- As2 Bio Inc · corp_trust
Screen this organization
A dated, signed PDF of the compliance screen for FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.
Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf
Questions and answers
- Who funds FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS?
- FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS (Texas) receives grants from 65 organizations whose IRS filings report $7,300,238 to it, the largest being THE MARNIER-LAPOSTOLLE FOUNDATION ($4,156,205). 33 of them have funded it in more than one year.
- How many funders does FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS have?
- IRS filings report 65 organizations giving $7,300,238 in grants to FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS, 33 of which have funded it in more than one year.
- Who is the largest funder of FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS?
- THE MARNIER-LAPOSTOLLE FOUNDATION is the largest funder on record, with $4,156,205 in grants. The full list of funders is on this page.
- How can an organization like FOUNDATION FOR ANGELMAN SYNDROME THERAPEUTICS find more funders?
- Start with the funders already giving here, then look at the foundations that back similar organizations in Texas. The funding by cause and by state pages list the largest funders for a given area and how to approach them.
These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2024 (financials across 2017–2024), and the filings of 65 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 22, 2026. What this page cannot tell you · view filing