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New York · Nonprofit

THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION

THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION (New York) receives grants from 167 organizations whose IRS filings report $9,954,928 to it, the largest being FIDELITY INVESTMENTS CHARITABLE GIFT FUND ($2,186,916). 96 of them have funded it in more than one year, and 69% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.

Revenue FY2024
$15M
Funders on record
167
Grants received
$10.0M
Net assets
$22M
96/167 repeat funderspeak grant-dependency 21%
01What it does

What The Zachary & Elizabeth M Fisher Center for Alzheimer's Research Foundation does

Mission

The zachary and elizabeth m. Fisher center for alzheimer's research foundation is dedicated to attacking the scourge of alzheimer's disease through a 3-pronged assault focused on understanding the cause of alzheimer's disease (ad), improving the care of people living with the disease to enhance their quality of life and that of their caregivers and families, and finding a cure.

As stated on its FY2024 Form 990.

Programs

  1. The zachary and elizabeth m. Fisher center for research on alzheimer's disease:the principal activity of the fisher center for alzheimer's research foundation is to provide funding to the fisher center lab at the rockefeller university, one of the largest and most modern facilities in the world dedicated to solving the puzzle of alzheimer's disease. The lab is currently led by newly appointed director, dr. Nathaniel heintz, the james and marilyn simons professor at the rockefeller university. The fisher center has provided researchers around the globe with a conceptual framework for understanding the disease process and continues to be at the forefront of one day finding a cure for alzheimer's disease.

    $3,500,000 spentof which $3,500,000 as grants
    68% of program spending
  2. A grant was made to the fisher alzheimer's disease education and resource program at nyu grossman school of medicine where dr. Martin sadowski and his team focus on the roles of peroxiredoxin-6, a protein encoded by the prdx6 gene and a member of the peroxiredoxin family of antioxidant enzymes, that is progressively emerging as a possible therapeutic target for alzheimer's disease.

    $400,000 spentof which $400,000 as grants
    8% of program spending
  3. The fisher center foundation information program:our information program promotes disease awareness, education and resources for people with alzheimer's, their families, friends, and caregivers. Information is dispersed through social networks, electronic and physical mailings, transit ads, and the foundation's website, alzinfo.org. The site is updated regularly to provide comprehensive data about alzheimer's disease, recent research studies and findings, treatment and disease management. The site has over 475,000 unique visitors a year. Our tri-annual magazine, preserving your memory , circulates 65,000 copies per issue and continues to win awards based on its editorial content as it addresses reader concerns over diagnosis and progress of alzheimer's disease. Our free bi-weekly e-newsletter, alzheimer's research news you can use, continues to be a highly reviewed alzheimer's and dementia e-newsletter with over 13,000 subscribers. Our social media presence continues to grow, with nearly 10,000 facebook followers, driving people to our website to seek out other information program materials. Our transit ads, a recent addition to our program this year, successfully drove thousands…

    $143,467 spentof which $115,657 as grants$3,853 earned by the program
    3% of program spending
  4. Rockefeller university fellowship:the fisher center foundation has provided funding for the fisher fellows in neuroscience program, a partnership to financially support five of the most outstanding third- and fourth-year students in the david rockefeller graduate program.rockefeller university greengard professorship grant: the fisher center foundation has provided funding for the paul greengard professorship in neuroscience at rockefeller university in honor of the late nobel laureate and his 35-year tenure with the university.imagine institute, paris, france:a grant was given to a european center of research on genetic diseases to investigate whether the structure of amyloid proteins is changed, particularly if protein aggregates, which are toxic for synapses, are decreased. In this hypothesis, masitinib may decrease protease release by mast cells, which may be responsible for generation of protein aggregates, and test whether masitinib is able to block lesions spreading after prions like proteins inoculation. This project will reveal the role of mast cell and kinases in the pathophysiology of alzheimer's disease. A better understanding of its mechanisms may define the best…

    $1,096,539 spentof which $128,000 as grants
    21% of program spending

The 4 programs described on its FY2023 Form 990, listed largest first by expense. Program spending in total: $5,140,006.

02The organization over time

The organization over time

Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20172017 Revenue 100 ($7.8M) Expenses 100 ($4.6M) Net assets 100 ($23M)2018 Revenue 67 ($5.2M) Expenses 96 ($4.4M) Net assets 98 ($23M)2019 Revenue 117 ($9.1M) Expenses 101 ($4.7M) Net assets 123 ($29M)2020 Revenue 128 ($10.0M) Expenses 142 ($6.6M) Net assets 139 ($32M)2021 Revenue 128 ($10M) Expenses 326 ($15M) Net assets 131 ($30M)2022 Revenue 91 ($7.1M) Expenses 269 ($12M) Net assets 88 ($20M)2023 Revenue 134 ($10M) Expenses 145 ($6.7M) Net assets 116 ($27M)2024 Revenue 186 ($15M) Expenses 486 ($22M) Net assets 95 ($22M)
'17'18'19'20'21'22'23'24
Revenue (186)Expenses (486)Net assets (95)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2021 to 2022, from $41M to $30M (−26%).

$27M
$26M
$32M
$35M
$41M
$30M
$33M
$36M
'17'18'19'20'21'22'23'24
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2017
2018
2019
2020
2021
2022
2023
2024
ContributionsProgram revenueInvestmentOther

90% of THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION’s revenue is contributions — more reliant on donations than three-quarters of its peers (7% for the typical peer).

This organization
Typical peer · 4,743 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 3 of the last 8 reported years ran a deficit.

$3.2M
’17
$793k
’18
$4.5M
’19
$3.4M
’20
−$5.1M
’21
−$5.4M
’22
$3.7M
’23
−$8.0M
’24
2.5
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Chief executive

Lucretia Holden

Executive director

Board chair

Barry R Sloane

Chairman/treasurer

As listed on its FY2024 Form 990.

The chief executive listed changed between the FY2018 and FY2019 filings.

'17'18'19'20'21'22'23'24
Listed1717161413111314
Joined·+1+1+1+1+1+4+1
No longer listed·1232320
03Who funds it

Who funds it, year by year

2017 → 2023: the base broadened from 36 funders to 56 funders, grant income rose $433k → $1.2M.

41 of 167 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 69% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

From the IRS filings of THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION’s funders (the co-funder graph). Top 30 of 167 funders by total. Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION has a broad base — no single funder exceeds 22% of grant income, and it takes 6 funders to reach half.

the vertical line marks half of all grant income — 6 funders to its left

75% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION.

22%
largest funder
38%
top three
~13
effective funders

Largest funder’s share by year: 2017 25% · 2018 18% · 2019 22% · 2020 24% · 2021 20% · 2022 22% · 2023 20% — diversifying over time.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How long its funders stay

35% of THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION's funders are still giving 3 years after their first grant; 57% give in more than one year at all.

first grant+1y+2y+3y+4y+5y+6y

Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.

Where its funders are

69% of THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION's grant income arrives through donor-advised or pass-through sponsors, whose addresses record where the money is held rather than where the donor is. Of the $3.1M that is directly attributable, 78% of it comes from funders outside New York, across 31 states.

ME
WA
ID
MT
MN
IL
MI
NY
MA
NV
WY
SD
IA
IN
PA
NJ
CT
CA
UT
MO
KY
VA
MD
DE
AZ
NC
DC
AL
GA
TX
FL

In-state vs out-of-state, by year

’17
’18
’19
’20
’21
’22
’23
New York out of state home

Funder states come from each funder’s own filing. $6.9M arriving through sponsors registered in 23 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION is better cushioned than half of the 4,580 health nonprofits its size.

Operating margin−55% · bottom quartile
Months of reserve2.5mo · above the median
Revenue growth (annualized)9% · above the median

this organization peer median middle 50% of peers· 4,580 health nonprofits $10M–$100M, FY2024

Organizations like THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In New York

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

92% of spending goes to programs.

Program 92%Management 6%Fundraising 3%

Governance

10
board members
100%
independent
✓Conflict-of-interest policy✓Whistleblower policy✓Document retention✓Board reviewed the 990✓Audited financials

Public support

81%

Share of support from the public (Schedule A) — the basis for its public-charity status.

Footprint & structure

Files a return copy in 20 states

NH
MN
IL
MI
NY
MA
OR
RI
CA
KY
WV
MD
KS
TN
SC
HI
MS
AL
GA
FL

Screen this organization

A dated, signed PDF of the compliance screen for THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION?
THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION (New York) receives grants from 167 organizations whose IRS filings report $9,954,928 to it, the largest being FIDELITY INVESTMENTS CHARITABLE GIFT FUND ($2,186,916). 96 of them have funded it in more than one year, and 69% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
How many funders does THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION have?
IRS filings report 167 organizations giving $9,954,928 in grants to THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION, 96 of which have funded it in more than one year.
Who is the largest funder of THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION?
FIDELITY INVESTMENTS CHARITABLE GIFT FUND is the largest funder on record, with $2,186,916 in grants. The full list of funders is on this page.
How can an organization like THE ZACHARY & ELIZABETH M FISHER CENTER FOR ALZHEIMER'S RESEARCH FOUNDATION find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in New York. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2024 (financials across 2017–2024), and the filings of 167 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing