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California · Nonprofit

GLOBAL COALITION FOR ADAPTIVE RESEARCH INC

GLOBAL COALITION FOR ADAPTIVE RESEARCH INC (California) receives grants from 11 organizations whose IRS filings report $5,697,911 to it, the largest being National Foundation For Cancer Research ($1,837,688). 5 of them have funded it in more than one year.

Revenue FY2025
$32M
Funders on record
11
Grants received
$5.7M
Net assets
$44M
5/11 repeat funderspeak grant-dependency 52%
01What it does

What Global Coalition for Adaptive Research Inc does

Mission

Our mission is pioneering collaborative, innovative clinical trials to speed the discovery and development of cures.

As stated on its FY2025 Form 990.

Programs

  1. Gbm agile (glioblastoma adaptive global innovative learning environment) is uniquely designed as a long-standing platform with the ability to test multiple therapies at the same time against a common control (or standard of care). The purpose is to evaluate multiple investigational treatments for either newly diagnosed or recurrent glioblastoma to determine if any of these study treatment(s) improve overall survival as compared to standard treatments.

    $27,443,955 spentof which $19,670 as grants$26,667,789 earned by the program
    92% of program spending
  2. Other ongoing programs or programs in development gcar serves as the regulatory sponsorship of the military and veterans ptsd adaptive platform clinical trial (m-pact). Partnering with operational medical systems, part of the defense health agency, gcar is conducting an adaptive platform trial at is evaluating multiple pharmacotherapeutic interventions for the treatment of ptsd for active-duty service members and veterans with ptsd at multiple clinical sites in the us. This program is supported by a project team that also includes representatives from the u.s. Air force, army, navy, and special operations command. Gcar is committed to designing, launching, and overseeing several initiatives currently in development to rapidly and efficiently evaluate new treatments for rare and lethal diseases, including pancreatic cancer, biliary tract cancer, high and low grade serous ovarian cancer, and neurofibromatosis. Gcar also supports education, outreach, and clinical community engagement to address these urgent unmet needs.

    $2,463,891 spent$2,867,102 earned by the program
    8% of program spending

The 2 programs described on its FY2025 Form 990, listed largest first by expense. Program spending in total: $29,907,846.

02The organization over time

The organization over time

Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20172017 Expenses 100 ($106k) Net assets -4 ($-255881)2018 Revenue 100 ($2.5M) Expenses 2331 ($2.5M) Net assets -1 ($-48527)2019 Revenue 472 ($12M) Expenses 4937 ($5.2M) Net assets 100 ($6.6M)2020 Revenue 628 ($16M) Expenses 9872 ($10M) Net assets 79 ($5.3M)2021 Revenue 1533 ($39M) Expenses 18137 ($19M) Net assets 405 ($27M)2022 Revenue 1401 ($35M) Expenses 22746 ($24M) Net assets 570 ($38M)2023 Revenue 1139 ($29M) Expenses 28060 ($30M) Net assets 602 ($40M)2024 Revenue 1096 ($28M) Expenses 29179 ($31M) Net assets 591 ($39M)2025 Revenue 1285 ($32M) Expenses 30797 ($33M) Net assets 666 ($44M)
'17'18'19'20'21'22'23'24'25
Revenue (1285)Expenses (30797)Net assets (666)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2019 to 2020, from $7.4M to $28M (+283%).

$44k
$109k
$7.4M
$28M
$41M
$60M
$60M
$64M
$78M
'17'18'19'20'21'22'23'24'25
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2018
2019
2020
2021
2022
2023
2024
2025
ContributionsProgram revenueInvestmentOther

3% of GLOBAL COALITION FOR ADAPTIVE RESEARCH INC’s revenue is contributions — about as donation-reliant as the typical peer (7% for the typical peer).

This organization
Typical peer · 4,743 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 4 of the last 9 reported years ran a deficit.

−$106k
’17
$57k
’18
$6.7M
’19
$5.4M
’20
$20M
’21
$11M
’22
−$931k
’23
−$3.2M
’24
−$164k
’25
3.0
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Chief executive

Meredith Buxton

Chief executive officer/president

Board chair

Faramarz Yousefzadeh Jd Llm

Chairman of the board

As listed on its FY2025 Form 990.

The chief executive listed changed between the FY2019 and FY2020 filings.

'18'19'20'21'22'23'24'25
Listed810111518181818
Joined·+4+2+6+7+1+2+0
No longer listed·2124120
03Who funds it

Who funds it, year by year

2018 → 2023: the base broadened from 2 funders to 5 funders, grant income fell $1.3M → $825k.

4 of 11 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 6% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

From the IRS filings of GLOBAL COALITION FOR ADAPTIVE RESEARCH INC’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

GLOBAL COALITION FOR ADAPTIVE RESEARCH INC leans on a few funders — its largest provides 32% of grant income and the top three 85%; half comes from just 2 funders.

the vertical line marks half of all grant income — 2 funders to its left

100% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund GLOBAL COALITION FOR ADAPTIVE RESEARCH INC.

32%
largest funder
85%
top three
~4
effective funders

Largest funder’s share by year: 2018 57% · 2019 46% · 2020 77% · 2021 49% · 2022 100% · 2023 61% — growing more concentrated.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How long its funders stay

43% of GLOBAL COALITION FOR ADAPTIVE RESEARCH INC's funders are still giving 3 years after their first grant; 45% give in more than one year at all.

first grant+1y+2y+3y+4y

Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.

Where its funders are

GLOBAL COALITION FOR ADAPTIVE RESEARCH INC draws 100% of its grant income from funders outside California, across 6 states in all.

NY
MA
PA
CT
CA
MD

In-state vs out-of-state, by year

’18
’19
’20
’21
’22
’23
California out of state home

Funder states come from each funder’s own filing. $322k arriving through sponsors registered in 4 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

GLOBAL COALITION FOR ADAPTIVE RESEARCH INC has grown faster than three-quarters of the 2,843 health nonprofits its size.

Operating margin−1% · below the median
Months of reserve3.0mo · above the median
Revenue growth (annualized)44% · top quartile

this organization peer median middle 50% of peers· 2,843 health nonprofits $10M–$100M, FY2025

Organizations like GLOBAL COALITION FOR ADAPTIVE RESEARCH INC

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In California

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

92% of spending goes to programs.

Program 92%Management 8%Fundraising 0%

Governance

8
board members
63%
independent
✓Conflict-of-interest policy✓Whistleblower policy✓Document retention✓Board reviewed the 990✓Audited financials

Public support

18%

Share of support from the public (Schedule A) — the basis for its public-charity status.

Footprint & structure

Files a return copy in 1 state

CA

Part of a family of 1 related entity

  • Spark Coalition Inc · exempt

Screen this organization

A dated, signed PDF of the compliance screen for GLOBAL COALITION FOR ADAPTIVE RESEARCH INC: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds GLOBAL COALITION FOR ADAPTIVE RESEARCH INC?
GLOBAL COALITION FOR ADAPTIVE RESEARCH INC (California) receives grants from 11 organizations whose IRS filings report $5,697,911 to it, the largest being National Foundation For Cancer Research ($1,837,688). 5 of them have funded it in more than one year.
How many funders does GLOBAL COALITION FOR ADAPTIVE RESEARCH INC have?
IRS filings report 11 organizations giving $5,697,911 in grants to GLOBAL COALITION FOR ADAPTIVE RESEARCH INC, 5 of which have funded it in more than one year.
Who is the largest funder of GLOBAL COALITION FOR ADAPTIVE RESEARCH INC?
National Foundation For Cancer Research is the largest funder on record, with $1,837,688 in grants. The full list of funders is on this page.
How can an organization like GLOBAL COALITION FOR ADAPTIVE RESEARCH INC find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in California. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2018–2025), and the filings of 11 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing