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California · Nonprofit

PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY

PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY (California) receives grants from 28 organizations whose IRS filings report $522,733,037 to it, the largest being Silicon Valley Community Foundation ($405,253,500). 15 of them have funded it in more than one year, and 82% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.

Revenue FY2025
$180M
Funders on record
28
Grants received
$523M
Net assets
$276M
15/28 repeat fundersgrants exceed reported revenue in one year
01What it does

What Parker Institute for Cancer Immunotherapy does

Mission

The Parker Institute for Cancer Immunotherapy's (pici) mission is to develop and accelerate access to breakthrough cancer therapies, curating innovation from discovery to patient access.

As stated on its FY2025 Form 990.

Program

  1. Parker Institute for Cancer Immunotherapy (pici) encourages advances in cancer immunotherapy research, collaboration, and discovery, and the translation of these advances into cures and treatments for the benefit of patients. To do this, pici partners with its consortium of preeminent hospitals and academic research centers to conduct its discovery and clinical research and provides its partners with shared research resources, such as scientific equipment, consumables, bioinformatics analysis, and a specimen biobank. Pici also funds and otherwise supports cancer immunotherapy research within its consortium.

    $46,776,153 spentof which $3,623,255 as grants$1,240,750 earned by the program
    100% of program spending

The program described on its FY2025 Form 990. Program spending in total: $46,776,153.

02The organization over time

The organization over time

Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20172017 Revenue 100 ($66M) Expenses 100 ($55M) Net assets 100 ($17M)2018 Revenue 172 ($113M) Expenses 121 ($66M) Net assets 380 ($64M)2019 Revenue 247 ($163M) Expenses 143 ($78M) Net assets 883 ($149M)2020 Revenue 100 ($66M) Expenses 128 ($70M) Net assets 860 ($145M)2021 Revenue 259 ($171M) Expenses 96 ($53M) Net assets 1946 ($328M)2022 Revenue 50 ($33M) Expenses 114 ($62M) Net assets 1483 ($250M)2023 Revenue 36 ($24M) Expenses 78 ($43M) Net assets 1202 ($202M)2024 Revenue 102 ($67M) Expenses 100 ($54M) Net assets 1102 ($185M)2025 Revenue 273 ($180M) Expenses 98 ($54M) Net assets 1643 ($276M)
'17'18'19'20'21'22'23'24'25
Revenue (273)Expenses (98)Net assets (1643)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2020 to 2021, from $153M to $380M (+149%).

$18M
$68M
$159M
$153M
$380M
$307M
$255M
$224M
$285M
'17'18'19'20'21'22'23'24'25
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2017
2018
2019
2020
2021
2022
2023
2024
2025
ContributionsProgram revenueInvestmentOther

97% of PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY’s revenue is contributions — more reliant on donations than three-quarters of its peers (1% for the typical peer).

This organization
Typical peer · 2,214 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 3 of the last 9 reported years ran a deficit.

$11M
’17
$47M
’18
$85M
’19
−$3.8M
’20
$118M
’21
−$29M
’22
−$19M
’23
$12M
’24
$126M
’25
8.4
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Chief executive

Karen E Knudsen Costello

CEO as of 03/2025

Board chair

Sean N Parker

Chair of the board & director

As listed on its FY2025 Form 990.

'17'18'19'20'21'22'23'24'25
Listed191123252626262526
Joined·+0+13+4+5+4+3+1+2
No longer listed·81244321
03Who funds it

Who funds it, year by year

2017 → 2023: the base broadened from 3 funders to 8 funders, grant income fell $81M → $1.3M.

11 of 28 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 82% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

From the IRS filings of PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY leans on a few funders — its largest provides 78% of grant income and the top three 95%; half comes from just 1 funder.

the vertical line marks half of all grant income — 1 funder to its left

88% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY.

78%
largest funder
95%
top three
~2
effective funders

Largest funder’s share by year: 2017 74% · 2018 100% · 2019 84% · 2020 87% · 2021 96% · 2022 41% · 2023 59% — diversifying over time.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How long its funders stay

40% of PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY's funders are still giving 3 years after their first grant; 54% give in more than one year at all.

first grant+1y+2y+3y+4y+5y

Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.

Where its funders are

82% of PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY's grant income arrives through donor-advised or pass-through sponsors, whose addresses record where the money is held rather than where the donor is. Of the $95M that is directly attributable, 64% of it comes from California funders.

NY
NJ
CA
DE
DC
AL

In-state vs out-of-state, by year

’17
’18
’19
’20
’21
’22
’23
California out of state home

Funder states come from each funder’s own filing. $428M arriving through sponsors registered in 9 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY runs a healthier operating margin than three-quarters of the 1,256 health nonprofits its size.

Operating margin70% · top quartile
Months of reserve8.4mo · top quartile
Revenue growth (annualized)13% · top quartile

this organization peer median middle 50% of peers· 1,256 health nonprofits over $100M, FY2025

Organizations like PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In California

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

87% of spending goes to programs.

Program 87%Management 12%Fundraising 1%

Governance

15
board members
93%
independent
✓Conflict-of-interest policy✓Whistleblower policy✓Document retention✓Board reviewed the 990✓Audited financials

Footprint & structure

Files a return copy in 37 states

AK
ME
NH
WA
ND
MN
IL
WI
MI
NY
MA
OR
NV
OH
PA
NJ
CT
RI
CA
CO
KY
WV
VA
MD
NM
KS
AR
TN
NC
SC
DC
HI
OK
MS
AL
GA
FL

Part of a family of 4 related entities

  • Maveric LLC · disregarded
  • Sean N Parker Foundation · exempt
  • Economic Innovation Group Inc · exempt
  • Paratope Inc · exempt

Screen this organization

A dated, signed PDF of the compliance screen for PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY?
PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY (California) receives grants from 28 organizations whose IRS filings report $522,733,037 to it, the largest being Silicon Valley Community Foundation ($405,253,500). 15 of them have funded it in more than one year, and 82% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
How many funders does PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY have?
IRS filings report 28 organizations giving $522,733,037 in grants to PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY, 15 of which have funded it in more than one year.
Who is the largest funder of PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY?
Silicon Valley Community Foundation is the largest funder on record, with $405,253,500 in grants. The full list of funders is on this page.
How can an organization like PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in California. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2017–2025), and the filings of 28 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 22, 2026. What this page cannot tell you · view filing