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Tennessee · Nonprofit

ST JUDE CHILDREN'S RESEARCH HOSPITAL INC

ST JUDE CHILDREN'S RESEARCH HOSPITAL INC (Tennessee) receives grants from 7355 organizations whose IRS filings report $940,530,867 to it, the largest being FIDELITY INVESTMENTS CHARITABLE GIFT FUND ($108,959,451). 4370 of them have funded it in more than one year.

Revenue FY2025
$2.2B
Funders on record
7,355
Grants received
$941M
Net assets
$12.6B
4370/7355 repeat funderspeak grant-dependency 12%
01What it does

What St Jude Children's Research Hospital Inc does

Mission

The mission of st. Jude children's research hospital is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of our founder danny thomas, no child is denied (continued on schedule o) treatment based on race, religion or a family's ability to pay.

As stated on its FY2025 Form 990.

Programs

  1. Research: the current basic science and clinical research at the hospital includes work in gene therapy, chemotherapy, the biochemistry of normal and cancerous cells, radiation treatment, blood diseases, resistance to therapy, viruses, neurological diseases, hereditary diseases, influenza, pediatric aids and physiological effects of catastrophic illnesses.

    $883,215,145 spentof which $178,680 as grants$3,020 earned by the program
    50% of program spending
  2. Patient care: the hospital provided 17,927 inpatient days of care during the year. Our bone marrow transplantation program accounted for 3,805 or 21% of those inpatient days. Patients made 74,651 clinic registrations during the year.

    $726,650,059 spentof which $3,636,000 as grants$143,039,289 earned by the program
    41% of program spending
  3. Education and training: as part of its mission, the institution has developed a global initiative (st. Jude global) to improve the survival rates of children with cancer and other catastrophic diseases worldwide. St. Jude global accomplishes this by sharing knowledge, technology and organizational skills, helping to implement new approaches to treat pediatric cancer globally, and developing regional networks committed to eradicating cancer in children. This mission will be achieved by focusing on three overriding goals: (1) to train the clinical workforce that will be required to meet our mission, (2) to develop and strengthen health systems and patient-centered initiatives that encompass the entire continuum of care required for children with cancer and non-malignant hematological (continued on schedule o) diseases, and (3) to advance knowledge in global pediatric oncology and hematology through research to sustain a continuous improvement in the level and quality of care delivered around the globe. These initiatives are spearheaded by st. Jude experts who work closely with healthcare professionals at our partner sites.the global initiative for childhood cancer, launched in 2018…

    $146,234,497 spentof which $7,171,881 as grants$10,498 earned by the program
    8% of program spending

The 3 programs described on its FY2024 Form 990, listed largest first by expense. Program spending in total: $1,756,099,701.

02The organization over time

The organization over time

Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20172017 Revenue 100 ($901M) Expenses 100 ($857M) Net assets 100 ($4.7B)2018 Revenue 109 ($981M) Expenses 111 ($951M) Net assets 114 ($5.3B)2019 Revenue 123 ($1.1B) Expenses 119 ($1.0B) Net assets 130 ($6.1B)2020 Revenue 137 ($1.2B) Expenses 129 ($1.1B) Net assets 141 ($6.6B)2021 Revenue 141 ($1.3B) Expenses 136 ($1.2B) Net assets 193 ($9.0B)2022 Revenue 154 ($1.4B) Expenses 149 ($1.3B) Net assets 199 ($9.3B)2023 Revenue 190 ($1.7B) Expenses 177 ($1.5B) Net assets 219 ($10.2B)2024 Revenue 223 ($2.0B) Expenses 207 ($1.8B) Net assets 243 ($11.3B)2025 Revenue 245 ($2.2B) Expenses 221 ($1.9B) Net assets 270 ($12.6B)
'17'18'19'20'21'22'23'24'25
Revenue (245)Expenses (221)Net assets (270)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2020 to 2021, from $6.7B to $9.2B (+36%).

$4.8B
$5.4B
$6.2B
$6.7B
$9.2B
$9.5B
$10.5B
$11.7B
$12.9B
'17'18'19'20'21'22'23'24'25
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2017
2018
2019
2020
2021
2022
2023
2024
2025
ContributionsProgram revenueInvestmentOther

Government-grant reliance: 2017 9% · 2018 8% · 2019 8% · 2020 9% · 2021 10% · 2022 9% · 2023 7% · 2024 7% · 2025 7%. Grants only. Government contracts and fees sit inside program revenue.

92% of ST JUDE CHILDREN'S RESEARCH HOSPITAL INC’s revenue is contributions — more reliant on donations than three-quarters of its peers (1% for the typical peer).

This organization
Typical peer · 2,211 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 0 of the last 9 reported years ran a deficit.

$44M
’17
$30M
’18
$87M
’19
$134M
’20
$106M
’21
$107M
’22
$188M
’23
$237M
’24
$311M
’25
0.1
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Chief executive

James R Downing

President/CEO

As listed on its FY2025 Form 990.

'17'18'19'20'21'22'23'24'25
Listed555455545146474752
Joined·+6+4+4+3+4+7+6+9
No longer listed·73569664
03Who funds it

Who funds it, year by year

2017 → 2023: the base broadened from 1584 funders to 2904 funders, grant income rose $37M → $152M.

258 of 7355 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 45% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

Left out of every figure on this page: $10.3B from 196 payers (the payer shares this organization's board, largest American Lebanese Syrian Associated Charities Inc); $31M from one payer (an institutional transfer, not a grant programme, largest Jeffrey Carlton Charitable Foundation); $6k from 2 payers (the payer's own filing calls it a related party, largest Amin Foundation). These are real filings, and they are not money ST JUDE CHILDREN'S RESEARCH HOSPITAL INC raised.

From the IRS filings of ST JUDE CHILDREN'S RESEARCH HOSPITAL INC’s funders (the co-funder graph). Top 30 of 7355 funders by total. Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

ST JUDE CHILDREN'S RESEARCH HOSPITAL INC has a broad base — no single funder exceeds 12% of grant income, and it takes 14 funders to reach half.

the vertical line marks half of all grant income — 14 funders to its left

67% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund ST JUDE CHILDREN'S RESEARCH HOSPITAL INC.

12%
largest funder
27%
top three
~29
effective funders

Largest funder’s share by year: 2017 16% · 2018 12% · 2019 12% · 2020 12% · 2021 35% · 2022 11% · 2023 11% — diversifying over time.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How long its funders stay

73% of ST JUDE CHILDREN'S RESEARCH HOSPITAL INC's funders are still giving 3 years after their first grant; 59% give in more than one year at all.

first grant+1y+2y+3y+4y+5y+6y

Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.

Where its funders are

ST JUDE CHILDREN'S RESEARCH HOSPITAL INC draws 94% of its grant income from funders outside Tennessee, across 49 states in all.

ME
VT
NH
WA
ID
MT
MN
IL
WI
MI
NY
MA
OR
NV
WY
SD
IA
IN
OH
PA
NJ
CT
RI
CA
UT
CO
NE
MO
KY
WV
VA
MD
DE
AZ
NM
KS
AR
TN
NC
SC
DC
HI
OK
LA
MS
AL
GA
TX
FL

In-state vs out-of-state, by year

’17
’18
’19
’20
’21
’22
’23
Tennessee out of state home

Funder states come from each funder’s own filing. $420M arriving through sponsors registered in 40 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

ST JUDE CHILDREN'S RESEARCH HOSPITAL INC runs a healthier operating margin than three-quarters of the 1,241 health nonprofits its size.

Operating margin14% · top quartile
Months of reserve0.1mo · below the median
Revenue growth (annualized)12% · top quartile

this organization peer median middle 50% of peers· 1,241 health nonprofits over $100M, FY2025

Government funding ST JUDE CHILDREN'S RESEARCH HOSPITAL INC receives

Grants and contracts to this organization from federal (USASpending) and state checkbooks, reconciled to its EIN. $1.1B on record — $1.1B federal, $122k state.

Federal$1.1B
grants $904.8Mcontracts $195.9M
17
18
19
20
21
22
23
24
25
26
Top agencies
  • Department of Health and Human Services$1.1B
  • Department of Defense$9.6M
  • National Science Foundation$5.5M
  • Department of Agriculture$1.9M
  • Department of Veterans Affairs$10k
State$122k
22
23
24
25
By state
  • FL$119k
  • MA$4k

Federal grants vs contracts are distinguished; state line items keep their reported category. Matched by name + geography (the BMF), so coverage is partial and precision-first.

Organizations like ST JUDE CHILDREN'S RESEARCH HOSPITAL INC

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In Tennessee

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

93% of spending goes to programs.

Program 93%Management 7%Fundraising 0%

Governance

37
board members
95%
independent
✓Conflict-of-interest policy✓Whistleblower policy✓Document retention✓Board reviewed the 990✓Audited financials

Public support

98%

Share of support from the public (Schedule A) — the basis for its public-charity status.

Footprint & structure

Files a return copy in 1 state

TN

Part of a family of 7 related entities

  • Children's Gmp LLC · disregarded
  • Thanks & Giving LLC · disregarded
  • The Right Words LLC · disregarded
  • St Jude Children's Research Hospital Graduate School of Biomedical Sciences · disregarded
  • St Jude Children's Research Hospital Home Care LLC · disregarded

Screen this organization

A dated, signed PDF of the compliance screen for ST JUDE CHILDREN'S RESEARCH HOSPITAL INC: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

A paid feature, included from the $75 plan up. Sign in to download.

Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds ST JUDE CHILDREN'S RESEARCH HOSPITAL INC?
ST JUDE CHILDREN'S RESEARCH HOSPITAL INC (Tennessee) receives grants from 7355 organizations whose IRS filings report $940,530,867 to it, the largest being FIDELITY INVESTMENTS CHARITABLE GIFT FUND ($108,959,451). 4370 of them have funded it in more than one year.
How many funders does ST JUDE CHILDREN'S RESEARCH HOSPITAL INC have?
IRS filings report 7355 organizations giving $940,530,867 in grants to ST JUDE CHILDREN'S RESEARCH HOSPITAL INC, 4370 of which have funded it in more than one year.
Who is the largest funder of ST JUDE CHILDREN'S RESEARCH HOSPITAL INC?
FIDELITY INVESTMENTS CHARITABLE GIFT FUND is the largest funder on record, with $108,959,451 in grants. The full list of funders is on this page.
How can an organization like ST JUDE CHILDREN'S RESEARCH HOSPITAL INC find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in Tennessee. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2017–2025), and the filings of 7355 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing