Massachusetts · Nonprofit
POLYBIO RESEARCH FOUNDATION INC
POLYBIO RESEARCH FOUNDATION INC (Massachusetts) receives grants from 15 organizations whose IRS filings report $3,154,148 to it, the largest being JSJN CHILDREN'S CHARITABLE TRUST (F/K/A WEBSTER CHARITABLE TRUST) ($1,000,000). 4 of them have funded it in more than one year.
- Revenue FY2024
- $4.3M
- Funders on record
- 15
- Grants received
- $3.2M
- Net assets
- $3.1M
What Polybio Research Foundation Inc does
Mission
We are a 501(c)3 transforming how complex chronic conditions like longcovid, me/cfs & post treatment lyme disease are studied, diagnosed, and treated. Polybio was founded by three scientists with complementary expertise (neuroscience, microbiology & genetics). We conceptualize research projects that identify root cause drivers of these conditions and build collaborative teams to make the projects a reality.
As stated on its FY2024 Form 990.
Program
We conceptualize collaborative research projects on me/cfs, longcovid and related infection-associated chronic conditions. Our projects study "root cause" drivers of these conditions, and combine the skills of virologists, neuroscientists, pathologists, microbiome experts and patient advocates to maximize impact.
$14,046,841 spentof which $13,813,525 as grants100% of program spending
The program described on its FY2024 Form 990. Program spending in total: $14,046,841.
The organization over time
Each line starts at 100 in 2020, so what you read is the shape rather than the size: 150 means half as much again as 2020, 50 means half. The number beside each label in the key is where it ended.
Balance sheet
Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2021 to 2022, from $615k to $14M (+2210%).
How it's funded, over time
Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.
Surplus & reserves
Operating surplus or deficit each year, and months of liquidity in hand. 2 of the last 5 reported years ran a deficit.
reserve
Leadership and staff
The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.
Chief executive
Amy Proal
Executive director
Board chair
Francis Brenner
Chair
As listed on its FY2024 Form 990.
Who funds it, year by year
2021 → 2023: the base held at 3 funders, grant income rose $45k → $135k.
7 of 15 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 5% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.
From the IRS filings of POLYBIO RESEARCH FOUNDATION INC’s funders (the co-funder graph). Top 14 of 15 funders by total. Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How concentrated its funding is
POLYBIO RESEARCH FOUNDATION INC leans on a few funders — its largest provides 32% of grant income and the top three 84%; half comes from just 2 funders.
the vertical line marks half of all grant income — 2 funders to its left
Largest funder’s share by year: 2021 57% · 2022 55% · 2023 92% — growing more concentrated.
“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Where its funders are
POLYBIO RESEARCH FOUNDATION INC draws 65% of its grant income from funders outside Massachusetts, across 5 states in all.
In-state vs out-of-state, by year
Funder states come from each funder’s own filing. $151k arriving through sponsors registered in 6 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Organizations like POLYBIO RESEARCH FOUNDATION INC
Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.
In Massachusetts
Nationally
Read directly from this organization’s own Form 990, as neutral context.
Where the money goes
99% of spending goes to programs.
Governance
Footprint & structure
Files a return copy in 1 state
Screen this organization
A dated, signed PDF of the compliance screen for POLYBIO RESEARCH FOUNDATION INC: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.
Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf
Questions and answers
- Who funds POLYBIO RESEARCH FOUNDATION INC?
- POLYBIO RESEARCH FOUNDATION INC (Massachusetts) receives grants from 15 organizations whose IRS filings report $3,154,148 to it, the largest being JSJN CHILDREN'S CHARITABLE TRUST (F/K/A WEBSTER CHARITABLE TRUST) ($1,000,000). 4 of them have funded it in more than one year.
- How many funders does POLYBIO RESEARCH FOUNDATION INC have?
- IRS filings report 15 organizations giving $3,154,148 in grants to POLYBIO RESEARCH FOUNDATION INC, 4 of which have funded it in more than one year.
- Who is the largest funder of POLYBIO RESEARCH FOUNDATION INC?
- JSJN CHILDREN'S CHARITABLE TRUST (F/K/A WEBSTER CHARITABLE TRUST) is the largest funder on record, with $1,000,000 in grants. The full list of funders is on this page.
- How can an organization like POLYBIO RESEARCH FOUNDATION INC find more funders?
- Start with the funders already giving here, then look at the foundations that back similar organizations in Massachusetts. The funding by cause and by state pages list the largest funders for a given area and how to approach them.
These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2024 (financials across 2020–2024), and the filings of 15 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing