Massachusetts · Nonprofit
OPENBIOME FOUNDATION INC
OPENBIOME FOUNDATION INC (Massachusetts) receives grants from 9 organizations whose IRS filings report $449,785 to it, the largest being GATES FOUNDATION ($135,476). 4 of them have funded it in more than one year.
- Revenue FY2024
- $2.2M
- Funders on record
- 9
- Grants received
- $450k
- Net assets
- $7.6M
What Openbiome Foundation Inc does
Mission
Openbiome's mission is to expand patient access to microbiome therapies and fuel scientific discoveries that shape the future of health.
As stated on its FY2024 Form 990.
Programs
Aligned with current fda policy, openbiome remains committed to ensuring that all patients suffering from c. Difficile infection continue to have safe, convenient, and affordable access to fecal microbiota transplantation (fmt) through their physician. In our collaboration with the university of minnesota (umn), under an active investigational drug application (ind), we continue to distribute fmt to our clinical network and are working with fda to ensure that all regulatory filings are kept current and compliant with the existing policy and guidance. We strive to make the path to treatment as simple as possible for patients and their doctors, while bringing a level of safety and standardization to the process that has set the standard for this emerging field. Openbiome provides fmt that has been manufactured by umn and has been rigorously screened. These ready-to-use fecal microbiota preparations allow physicians to devote their time and energy to treating patients, rather than the complexities of managing a stool donor program.
$1,390,228 spent$3,233,441 earned by the program60% of program spendingClinical research program: openbiome seeks to enable translational research on the human microbiome. To do so, we provide a suite of services to help investigators uncover the role of the gut microbiome in human health, and to discover how engineering it can drive better health outcomes. Our services include the provision of customized fecal microbiota preparations, study design and regulatory support for clinical trials, and bioinformatics and analytical services. Openbiome also sponsors its own studies investigating critical microbiome-related health conditions.
$39,484 spent$22,100 earned by the program2% of program spendingThe global microbiome conservancy (gmbc) program at openbiome partners with scientists around the world to conserve, study, and share underrepresented and at-risk human microbiome diversity. The gmbc has established a network of 80+ researchers in over three dozen countries and built a diverse collection of samples and bacterial isolates to spark scientific discovery and enable new solutions to microbiome-associated disease.the gmbc was established to solve the urgent need for a deeper, more globally representative understanding of the human microbiome that addresses the health concerns of all. A deeper understanding of the human microbiome is critical to solving global health challenges such as antimicrobial resistance, malnutrition, depression, as well as autoimmune and metabolic disorders that are linked to the communities of bacteria that live within us. However, our current body of knowledge, largely based on u.s. And european populations, is biased and vastly incomplete. As industrialization disrupts human microbiome diversity on a global scale, the window of opportunity to study and apply the full potential of the human microbiome is closing.to radically expand scientists'…
$897,620 spent$25,699 earned by the program39% of program spending
The 3 programs described on its FY2023 Form 990, listed largest first by expense. Program spending in total: $2,327,332.
The organization over time
Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.
Balance sheet
Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2018 to 2019, from $4.1M to $11M (+177%).
How it's funded, over time
Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.
Government-grant reliance: 2017 0% · 2018 1% · 2021 18% · 2022 41% · 2023 17% · 2024 3%. Grants only. Government contracts and fees sit inside program revenue.
5% of OPENBIOME FOUNDATION INC’s revenue is contributions — about as donation-reliant as the typical peer (51% for the typical peer).
Surplus & reserves
Operating surplus or deficit each year, and months of liquidity in hand. 3 of the last 8 reported years ran a deficit.
reserve
Leadership and staff
The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.
Chief executive
Julie O'Brien
Chief executive officer
Board chair
Neil Rasmussen
Director/board chair
As listed on its FY2024 Form 990.
Who funds it, year by year
2017 → 2022: the base narrowed from 2 funders to 1 funder, grant income fell $142k → $10k.
5 of 9 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 23% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.
From the IRS filings of OPENBIOME FOUNDATION INC’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How concentrated its funding is
OPENBIOME FOUNDATION INC leans on a few funders — its largest provides 30% of grant income and the top three 69%; half comes from just 2 funders.
the vertical line marks half of all grant income — 2 funders to its left
32% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund OPENBIOME FOUNDATION INC.
Largest funder’s share by year: 2017 58% · 2018 100% · 2019 56% · 2020 52% · 2021 66% · 2022 100% — growing more concentrated.
“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How long its funders stay
14% of OPENBIOME FOUNDATION INC's funders are still giving 2 years after their first grant; 44% give in more than one year at all.
Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2022, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.
Where its funders are
OPENBIOME FOUNDATION INC draws 100% of its grant income from funders outside Massachusetts, across 3 states in all.
In-state vs out-of-state, by year
Funder states come from each funder’s own filing. $104k arriving through sponsors registered in 5 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Against its field
OPENBIOME FOUNDATION INC is better cushioned than half of the 8,121 health nonprofits its size.
this organization peer median middle 50% of peers· 8,121 health nonprofits $1M–$10M, FY2024
Government funding OPENBIOME FOUNDATION INC receives
Grants and contracts to this organization from federal (USASpending) and state checkbooks, reconciled to its EIN. $57k on record.
- Department of Agriculture$30k
- Department of Health and Human Services$27k
Federal grants vs contracts are distinguished; state line items keep their reported category. Matched by name + geography (the BMF), so coverage is partial and precision-first.
Organizations like OPENBIOME FOUNDATION INC
Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.
In Massachusetts
Nationally
Read directly from this organization’s own Form 990, as neutral context.
Where the money goes
81% of spending goes to programs.
Governance
Public support
94%
Share of support from the public (Schedule A) — the basis for its public-charity status.
Footprint & structure
Files a return copy in 1 state
Screen this organization
A dated, signed PDF of the compliance screen for OPENBIOME FOUNDATION INC: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.
Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf
Questions and answers
- Who funds OPENBIOME FOUNDATION INC?
- OPENBIOME FOUNDATION INC (Massachusetts) receives grants from 9 organizations whose IRS filings report $449,785 to it, the largest being GATES FOUNDATION ($135,476). 4 of them have funded it in more than one year.
- How many funders does OPENBIOME FOUNDATION INC have?
- IRS filings report 9 organizations giving $449,785 in grants to OPENBIOME FOUNDATION INC, 4 of which have funded it in more than one year.
- Who is the largest funder of OPENBIOME FOUNDATION INC?
- GATES FOUNDATION is the largest funder on record, with $135,476 in grants. The full list of funders is on this page.
- How can an organization like OPENBIOME FOUNDATION INC find more funders?
- Start with the funders already giving here, then look at the foundations that back similar organizations in Massachusetts. The funding by cause and by state pages list the largest funders for a given area and how to approach them.
Play a game about who funds Openbiome →
These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2024 (financials across 2017–2024), and the filings of 9 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing