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Washington · Nonprofit

BENAROYA RESEARCH INSTITUTE AT VIRGINIA

BENAROYA RESEARCH INSTITUTE AT VIRGINIA (Washington) receives grants from 47 organizations whose IRS filings report $27,228,546 to it, the largest being BREAKTHROUGH T1D ($10,310,420). 30 of them have funded it in more than one year.

Revenue FY2025
$81M
Funders on record
47
Grants received
$27M
Net assets
$58M
30/47 repeat funderspeak grant-dependency 5%
01What it does

What Benaroya Research Institute at Virginia does

Mission

To advance the science that will predict, prevent, reverse, and cure diseases of the immune system such as autoimmune disease, allergy, and asthma.

As stated on its FY2025 Form 990.

Programs

  1. Translational immunology and advancements of the immune tolerance network (itn) are highlighted below:funding for the immune tolerance network (itn) was initially awarded to jerry nepom, md, phd, at bri in 2014 by the national institute of allergy and infectious diseases (niaid) of the national institutes of health (nih). It was later renewed for a second grant cycle in 2021, providing approximately $27 million annually to support itn. This research consortium, established in 1999, primarily focuses on developing new tolerogenic approaches for treating and preventing diseases in three clinical areas: asthma and allergic diseases, autoimmune diseases, and immune-mediated rejection of transplanted solid organs, tissues, and cells. Bri, as the prime recipient of this grant, is responsible for managing the overall grant from niaid, including overseeing all aspects of the network's infrastructure. As of 2022 following the retirement of dr. Nepom, dr. Jane buckner assumed the role of principal investigator of the itn grant. Dr. Buckner serves on the itn steering committee (nsc) and the itn network executive committee (nec), and played an active role in 2025 in both committees at its…

    $45,420,572 spentof which $28,621,618 as grants
    68% of program spending
  2. Interventional immunologystudying health to understand diseasein june 2025, a team of bri scientists lead by jane buckner, md, cate speake, phd, megan smithmyer, phd, and alex hu, phd, published findings from the sound life project, a unique longitudinal study investigating how healthy immune systems differ from each other. The study followed 100 healthy individuals for two years, and participants donated blood samples over 10 visits and self-reported information about diet, exercise, travel and health through weekly surveys.in this first publication, the investigators measured 174 different types of immune cells that circulate in the blood. They determined that 81 of these immune cell types did not change over time within an individual and compared the frequencies of those immune cell types across the group of 100 healthy participants, they found that these individuals could be divided into four distinct groups, called immunotypes, based on the cell populations in their immune systems. To better understand the features that defined the four immunotypes, the sound life project investigators also analyzed which genes were expressed and which proteins were produced in the immune…

    $10,652,973 spentof which $27,772 as grants
    16% of program spending
  3. Fundamental immunology or basic discoveryunderstanding how targeting specific regulatory cells could lead to new ways to treat systemic lupus erythematosus (sle)in november 2024, steve ziegler, phd, a principal investigator in bri's center for fundamental immunology, received a grant from the national institute of allergy and infectious diseases of the national institutes of health to investigate how a subset of regulatory cells is dysfunctional in controlling autoantibody production in individuals with sle.this work builds off decades of dr. Ziegler's previous research into foxp3, a critical gene that regulates the development and function of regulatory t cells (tregs), which help prevent the immune system from attacking the body's own tissues. Dr. Ziegler's research suggests that an alternative version of foxp3 may contribute to treg dysfunction and increase susceptibility to autoimmune diseases.dr. Ziegler has identified a specific group of regulatory cells, which normally help control antibody production, that are not working properly in sle patients. Similar issues with these cells also cause lupus-like symptoms in lab models. The grant will support a study using these lab…

    $7,090,274 spentof which $495,370 as grants
    11% of program spending
  4. Clinical research program bri oversees the clinical research program at virginia mason medical center (vmmc), uniquely combining the expertise of a world-renowned medical research institute with the care of a healthcare quality leader. The clinical research program supports vmmc clinical investigators in studies across a wide variety of autoimmune and immune-mediated diseases and conditions, as well as a broad range of other diseases such as cancer and cardiac disease. The clinical research program staff annually enrolls over 2,200 study participants into vmmc trials.innovation fund awardestablished in 2023, the innovation fund award is given twice a year to internal recipients at bri. The objective is to facilitate development and implementation of new technologies that will advance work across our institution, through the funding of collaborative projects. Each award is funded by philanthropy. Bri's regular track and research track faculty are award eligible. Projects are required to include two or more bri faculty and address innovations useful to multiple research groups within the institute. Further, it is required that the protocols and results generated in the project will…

    $3,820,545 spent$6,649,426 earned by the program
    6% of program spending

The 4 programs described on its FY2024 Form 990, listed largest first by expense. Program spending in total: $66,984,364.

02The organization over time

The organization over time

Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20172017 Revenue 100 ($68M) Expenses 100 ($72M) Net assets 100 ($46M)2018 Revenue 100 ($68M) Expenses 93 ($67M) Net assets 97 ($44M)2019 Revenue 108 ($73M) Expenses 100 ($71M) Net assets 111 ($51M)2020 Revenue 100 ($68M) Expenses 100 ($71M) Net assets 110 ($50M)2021 Revenue 56 ($38M) Expenses 52 ($37M) Net assets 120 ($55M)2022 Revenue 140 ($95M) Expenses 117 ($84M) Net assets 120 ($55M)2023 Revenue 122 ($82M) Expenses 116 ($83M) Net assets 113 ($52M)2024 Revenue 138 ($94M) Expenses 122 ($88M) Net assets 122 ($56M)2025 Revenue 120 ($81M) Expenses 113 ($81M) Net assets 126 ($58M)
'17'18'19'20'21'22'23'24'25
Revenue (120)Expenses (113)Net assets (126)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2018 to 2019, from $84M to $96M (+14%).

$90M
$84M
$96M
$100M
$104M
$100M
$94M
$96M
$95M
'17'18'19'20'21'22'23'24'25
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2017
2018
2019
2020
2021
2022
2023
2024
2025
ContributionsProgram revenueInvestmentOther

Government-grant reliance: 2017 76% · 2018 67% · 2019 66% · 2020 71% · 2021 71% · 2022 62% · 2023 70% · 2024 69% · 2025 70%. Grants only. Government contracts and fees sit inside program revenue.

90% of BENAROYA RESEARCH INSTITUTE AT VIRGINIA’s revenue is contributions — more reliant on donations than three-quarters of its peers (7% for the typical peer).

This organization
Typical peer · 4,743 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 3 of the last 9 reported years ran a deficit.

−$3.8M
’17
$1.0M
’18
$1.8M
’19
−$3.6M
’20
$696k
’21
$11M
’22
−$862k
’23
$6.1M
’24
$545k
’25
0.7
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Board chair

Uli Chi Phd

Director/chair

As listed on its FY2025 Form 990.

'17'18'19'20'21'22'23'24'25
Listed272730301925242425
Joined·+5+7+5+16+11+1+3+4
No longer listed·545275233
03Who funds it

Who funds it, year by year

2017 → 2023: the base broadened from 9 funders to 21 funders, grant income fell $3.3M → $2.5M.

9 of 47 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 4% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

Left out of every figure on this page: $75M from 11 payers (the payer shares this organization's board, largest Virginia Mason Medical Center). These are real filings, and they are not money BENAROYA RESEARCH INSTITUTE AT VIRGINIA raised.

From the IRS filings of BENAROYA RESEARCH INSTITUTE AT VIRGINIA’s funders (the co-funder graph). Top 30 of 47 funders by total. Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

BENAROYA RESEARCH INSTITUTE AT VIRGINIA has a broad base — no single funder exceeds 38% of grant income, and it takes 3 funders to reach half.

the vertical line marks half of all grant income — 3 funders to its left

74% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund BENAROYA RESEARCH INSTITUTE AT VIRGINIA.

38%
largest funder
54%
top three
~6
effective funders

Largest funder’s share by year: 2017 82% · 2018 93% · 2019 72% · 2020 47% · 2021 58% · 2022 39% · 2023 20% — diversifying over time.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How long its funders stay

46% of BENAROYA RESEARCH INSTITUTE AT VIRGINIA's funders are still giving 3 years after their first grant; 64% give in more than one year at all.

first grant+1y+2y+3y+4y+5y+6y

Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.

Where its funders are

BENAROYA RESEARCH INSTITUTE AT VIRGINIA draws 84% of its grant income from funders outside Washington, across 14 states in all.

WA
MN
WI
MI
NY
MA
OH
PA
CT
CA
VA
MD
DE
GA

In-state vs out-of-state, by year

’17
’18
’19
’20
’21
’22
’23
Washington out of state home

Funder states come from each funder’s own filing. $1.1M arriving through sponsors registered in 8 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

BENAROYA RESEARCH INSTITUTE AT VIRGINIA's revenue grew 20% between 2017 and 2025.

Operating margin1% · below the median
Months of reserve0.7mo · below the median
Revenue growth (annualized)2% · bottom quartile

this organization peer median middle 50% of peers· 2,843 health nonprofits $10M–$100M, FY2025

Government funding BENAROYA RESEARCH INSTITUTE AT VIRGINIA receives

Grants and contracts to this organization from federal (USASpending) and state checkbooks, reconciled to its EIN. $504.4M on record.

Federal$504.4M
grants $499.0Mcontracts $5.4M
17
18
19
20
21
22
23
24
25
26
Top agencies
  • Department of Health and Human Services$503.4M
  • Department of Defense$1.0M
  • Department of Veterans Affairs$6k

Federal grants vs contracts are distinguished; state line items keep their reported category. Matched by name + geography (the BMF), so coverage is partial and precision-first.

Organizations like BENAROYA RESEARCH INSTITUTE AT VIRGINIA

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In Washington

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

83% of spending goes to programs.

Program 83%Management 17%Fundraising 0%

Governance

14
board members
100%
independent
✓Conflict-of-interest policy✓Whistleblower policy✓Document retention–Board reviewed the 990✓Audited financials

Public support

83%

Share of support from the public (Schedule A) — the basis for its public-charity status.

Footprint & structure

Files a return copy in 1 state

WA

Part of a family of 333 related entities

  • Alegent Creighton Clinic · exempt
  • Alegent Creighton Health · exempt
  • Alegent Health - Bergan Mercy Health System · exempt
  • Alegent Health - Comm Mem Hospital of Mo Valley Ia · exempt
  • Alegent Health - Immanuel Medical Center · exempt

Screen this organization

A dated, signed PDF of the compliance screen for BENAROYA RESEARCH INSTITUTE AT VIRGINIA: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds BENAROYA RESEARCH INSTITUTE AT VIRGINIA?
BENAROYA RESEARCH INSTITUTE AT VIRGINIA (Washington) receives grants from 47 organizations whose IRS filings report $27,228,546 to it, the largest being BREAKTHROUGH T1D ($10,310,420). 30 of them have funded it in more than one year.
How many funders does BENAROYA RESEARCH INSTITUTE AT VIRGINIA have?
IRS filings report 47 organizations giving $27,228,546 in grants to BENAROYA RESEARCH INSTITUTE AT VIRGINIA, 30 of which have funded it in more than one year.
Who is the largest funder of BENAROYA RESEARCH INSTITUTE AT VIRGINIA?
BREAKTHROUGH T1D is the largest funder on record, with $10,310,420 in grants. The full list of funders is on this page.
How can an organization like BENAROYA RESEARCH INSTITUTE AT VIRGINIA find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in Washington. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2017–2025), and the filings of 47 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing