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Maryland · Public charity

Howard Hughes Medical Institute

The mission of the institute has remained constant since its founding in 1953. As its restated articles of incorporation state the primary purpose and objective of the Howard Hughes Medical Institute shall be the promotion of human knowledge by conducting discovery research and science education, principally within fields associated with…

$63M
Granted FY2025(still arriving)
31
Itemized grants FY2025
44
Organizations funded FY2024
11%
First-time grantees FY2024
Read the full brief
Itemized, FY2025
$8.8M
The rest is grants the schedule does not break out
Median grant, FY2025
$20,000
Largest grant, FY2025
$3,062,953
Organizations funded a year
44 to 147
FY2018 to FY2024
States reached, FY2025
15
Total assets, FY2025
$29.5B

How open it is to new grantees

In FY2024, 11% of the organizations Howard Hughes Medical Institute funded were first-time grantees, receiving 3% of its grant dollars.

New vs renewed · share of each year

In FY2024, 97% of grant dollars renewed an existing relationship; $1.3M went to new ones.

50%100%’18’19’20’21’22’23’24
RenewedFirst-time

Where new relationships form · theme of each grantee’s first grant

’18’19’20’21’22’23’24
EducationHealthScience & TechPhilanthropyRecreation & SportsHuman ServicesOther
How this is measured
First-time means a grantee’s first year in the filing window; renewed means funded in an earlier year too. The renewed share climbs naturally as a portfolio matures, so the signal is a year that bucks it (a wave of new grantees). The earliest year is left-censored: relationships that predate the data read as new. Theme is the grantee’s IRS cause.
The numbers by year
Fiscal yearOrganizations fundedTo those organizationsFirst-time grantees
FY2025still arriving25$4.9M32%
FY202444$48M11%
FY2023140$96M6%
FY202245$16M7%
FY2021147$23M77%
FY202047$30M26%
FY201979$19M15%
FY2018103$57M65%
100% classified

What it funded, over time

Every grant placed by its stated purpose and the recipient’s mission, by year, FY2017 to 2025.

Education$280MHealth$91MScience & Tech$21MEnvironment$1.7MHousing & Shelter$217kInternational$61kCommunity Improvement$40k

Where its grants go

Grant dollars by states, across the years we hold.

Which US states its grants reach

AK
ME
VT
NH
WA
ID
MT
MN
IL
WI
MI
NY
MA
OR
NV
WY
SD
IA
IN
OH
PA
NJ
CT
RI
CA
UT
CO
NE
MO
KY
WV
VA
MD
DE
AZ
NM
KS
AR
TN
NC
SC
DC
HI
OK
LA
MS
AL
GA
TX
FL

Top grantees

Largest recipients by total granted, FY2017 to FY2025, and the share of each one’s budget the grants supplied at peak.

GranteeTotal grantedYearsShare of their budget
University of California San Francisco$12,898,8258n/a
Regents of the University of California at Berkeley$11,043,5067n/a
Regents Univ of California$10,142,4158n/a
University of Maryland College Park$7,550,0007n/a
University of Texas$7,414,4525n/a
Regents of the University of California at San Diego$6,823,6566n/a
University of Washington$6,604,7676n/a
University of Massachusetts$6,478,4205n/a
University of Pittsburgh$6,325,00020%
Loudoun Education Foundation Inc$6,000,000492%
Show all 284 grantees
All grantees of Howard Hughes Medical Institute by total granted
GranteeTotal grantedYearsShare of their budget
University of California San Francisco$12,898,8258n/a
Regents of the University of California at Berkeley$11,043,5067n/a
Regents Univ of California$10,142,4158n/a
University of Maryland College Park$7,550,0007n/a
University of Texas$7,414,4525n/a
Regents of the University of California at San Diego$6,823,6566n/a
University of Washington$6,604,7676n/a
University of Massachusetts$6,478,4205n/a
University of Pittsburgh$6,325,00020%
Loudoun Education Foundation Inc$6,000,000492%
Vanderbilt University$5,572,90450%
Regents of the University of Colorado$5,470,0336n/a
The Trustees of Princeton University$5,078,02560%
The Research Foundation for The State University of New York$4,672,26660%
Washington University$4,578,89780%
The Salk Institute for Biological Studies$4,501,45561%
Fred Hutchinson Cancer Research Center$4,380,47451%
Montgomery County Public Schools Educational Foundation Inc$4,090,000374%
Marine Biological Lab$3,942,0003n/a
Rutgers the State University$3,888,5454n/a
University of Wisconsin Madison$3,546,2515n/a
Cold Spring Harbor Laboratory$3,466,69041%
Board of Trustees of Illinois State University$3,372,6004n/a
University of Alaska$3,358,6003n/a
Science Communication Lab Inc$3,300,0001n/a
California Institute of Technology$3,283,43150%
Rector & Visitors of the University of Virginia$3,119,5003n/a
The University of Texas Southwestern Medical Cente$3,019,3494n/a
University of North Carolina at Chapel Hill$2,922,8243n/a
Allen Institute$2,910,00022%
The Rockefeller University$2,885,98970%
William Marsh Rice University$2,580,00040%
The Ohio State University$2,560,0003n/a
Loyola Marymount University$2,560,00030%
University of Utah$2,554,6907n/a
The University of Montana$2,550,0002n/a
University of Vermont and State Agricultural College$2,550,0002n/a
Duke University$2,483,31750%
University of California Davis$2,380,0005n/a
Northeastern University$2,330,00040%
Northwestern University$2,194,90750%
University of Minnesota$2,050,6545n/a
Regents of the University of California at Riverside$2,035,0723n/a
Loudoun County Public Schools$2,000,0001n/a
James Madison University$1,910,0004n/a
Regents of the University of California at Irvine$1,895,0004n/a
The Jackson Laboratory$1,842,00030%
Pennsylvania State University$1,803,0653n/a
Johns Hopkins University$1,799,18140%
Tufts Univ$1,792,8552n/a
The Broad Institute Inc$1,701,71450%
Iup Research Institute$1,695,000324%
Case Western Reserve University$1,669,01230%
Whitehead Institute for Biomedical Research$1,648,37760%
University of Vermont and State Agricultural College Foundation Inc$1,648,30513%
Oregon Health & Science University Foundation$1,645,68112%
Regents of the University of California$1,591,6004n/a
University of California San Francisco Foundation$1,493,00420%
Arizona State University$1,465,1833n/a
Trustees of Boston University$1,375,00040%
Virginia Polytechnic Institute & State University$1,329,6853n/a
Drexel University$1,315,00030%
Icahn School of Medicine at Mount Sinai$1,290,00020%
National Academy of Sciences$1,228,00030%
University of la Verne$1,213,06531%
National University$1,165,81220%
St Jude Children's Research Hospital Inc$1,152,13920%
The Board of Trustees of the University of Illinois$1,120,0004n/a
Western Washington University$1,100,0003n/a
Board of Regents of the University of California (Merced)$1,085,0003n/a
Regents of the University of Michigan$1,080,3674n/a
Dana-Farber Cancer Institute Inc$1,071,67120%
Cornell University$1,071,45830%
Boise State University$1,068,1883n/a
Syracuse University$1,060,00020%
Oregon State University$1,060,0002n/a
Wheaton College$1,060,00021%
California State University San Marcos Corporation$1,060,00025%
Kennesaw State University$1,060,0002n/a
University of Houston$1,060,0002n/a
Virginia Commonwealth University Foundat$1,060,00026%
Norfolk State University$1,060,0002n/a
Curators of the University of Missouri$1,060,0002n/a
Roosevelt University$1,060,00021%
Lawrence University of Wisconsin$1,060,00021%
Mount Mary University Inc$1,060,00023%
Framingham State Univ$1,060,0002n/a
Vassar College$1,060,00020%
Univ of Puerto Rico$1,060,0002n/a
Kalamazoo College$1,060,00021%
Wellesley College$1,060,00020%
Mercy University$1,060,00021%
University of St Thomas$1,060,00020%
President and Trustees of Bates College$1,060,00021%
DePauw University$1,060,00021%
The College of New Jersey$1,060,0002n/a
Davidson College$1,060,00021%
University of Northern Colorado$1,050,0003n/a
Oberlin College$1,050,00030%
Radford University$1,050,0003n/a
Chaminade University of Honolulu$1,050,00032%
Trinity College$1,050,00032%
University of South Dakota$1,050,0003n/a
Lawrence Technological University$1,050,00032%
Rochester Institute of Technology$1,050,00030%
Cal Poly Humboldt Sponsored Programs Foundation$1,050,00034%
University of Texas Rio Grande Valley$1,050,0003n/a
San Francisco State University$1,050,0003n/a
Kenyon College$1,050,00031%
Csu Fullerton Auxiliary Services Corporation$1,020,00012%
Nc State University$1,020,0001n/a
Researchamerica$1,005,00047%
University of Hawaii System$1,000,0001n/a
Delaware State University$1,000,00011%
Centre College$995,00021%
Florida State University Research Foundation Inc$983,66833%
Furman University$961,60020%
Memorial Sloan-Kettering Cancer Center$923,62160%
University of Wyoming$913,6682n/a
University of Wisconsin$913,6683n/a
Florida International University$903,6682n/a
Washington State University$853,6682n/a
Pomona College$833,06520%
Memorial Sloan-Kettering Cancer Center$820,0001n/a
The American Society for Cell Biology$817,15577%
Bryn Mawr College$813,06520%
Trustees of the College of the Holy Cross$809,50030%
Franklin & Marshall College$751,60030%
Gustavus Adolphus College$734,02520%
Chesapeake Bay Foundation Inc$690,00031%
Board of Regents of the University of Nebraska$665,0003n/a
Coker University$655,00022%
University of Richmond$655,00020%
Nature Forward$638,75058%
University of Connecticut$595,0003n/a
University of Kansas Center for Research Inc$589,50030%
Unversity of Oklahoma$572,6653n/a
North Carolina a & T State University$568,0653n/a
Trinity University$561,60020%
Sistema Universitario Ana G Mendez Incorporado$561,60020%
California State University Stanislaus$561,6002n/a
Dalton State College$561,6002n/a
Fordham University$561,60020%
Southern Illinois University Edwardsville$561,6002n/a
Gannon University$561,60020%
President and Fellows of Middlebury College$561,60020%
Clemson University$560,6663n/a
University of Rhode Island Foundation & Alumni Engagement$560,00032%
The University of Akron$559,5002n/a
Nebraska Wesleyan University$559,50021%
Emmanuel College$559,50020%
The Trustees of Mount Holyoke College$559,50020%
Allegheny College$559,50020%
Hartwick College$559,50021%
St John's University New York$559,50020%
Auburn University$559,5002n/a
Rollins College$559,50020%
College of Saint Benedict$535,00020%
Tuskegee University$535,00020%
Skidmore College$535,00020%
Trustees of Union College in the Town of Schenectady in the State of New York$535,00020%
Research Foundation of the City University of New York$535,00020%
Occidental College$535,00020%
Georgia Tech Research Corporation$535,00020%
Willamette University$535,00021%
Gettysburg College$533,06520%
California State University East Bay$529,5001n/a
Georgia Southern University Research and Service Foundationinc$523,06522%
University of Oregon$523,0652n/a
Whittier College$523,06521%
University of Portland$523,06520%
Georgia Gwinnett College$523,0652n/a
Providence College$523,06520%
Children's Hospital Corporation$520,00020%
Children's Hospital Medical Center$510,00020%
Baylor College of Medicine$506,11720%
Cleveland State University$505,0002n/a
The College of Wooster$505,00020%
Lane College$505,00021%
Marian University$505,00020%
University of Mississippi$505,0002n/a
Michigan State University$500,6662n/a
Montana State University$500,6662n/a
King University$500,66621%
The Howard University$500,66620%
Board of Regents Nevada System of Higher Education$500,6662n/a
Monmouth College$500,66621%
Texas A&M University$500,0001n/a
University of Georgia$493,0651n/a
Cal Poly Corporation$475,00010%
Georgia State University$475,0001n/a
West Virginia University Research Corporation$475,00010%
Rowan University$470,6661n/a
National Jewish Health$456,91320%
Emory University$450,45720%
North Carolina Central University$449,9233n/a
Mass General Brigham Incorporated$414,7191n/a
Carnegie Institution of Washington$414,69010%
Oregon Health & Science University$414,6901n/a
Oglethorpe University Inc$407,80020%
Simmons University$407,80020%
Fort Lewis College$407,8002n/a
Portland State University$407,8002n/a
Fairfield University$407,80020%
Xavier University$407,80020%
State University of Iowa$407,8002n/a
Fisk University$407,80021%
Otterbein University$407,80020%
Elon University$407,80020%
University of New Mexico$407,8002n/a
Stowers Institute for Medical Research$405,45711%
Association of American Universities Inc$403,16314%
Mass General Brigham Incorporated$392,2962n/a
The Cleveland Clinic Foundation$391,71420%
The Scripps Research Institute$388,63420%
Donald Danforth Plant Science Center$382,77321%
Trustees of Purdue University$372,7731n/a
Weill Medical College of Cornell Univers$372,7731n/a
Albert Einstein College of Medicine$331,23220%
UT Southwestern Medical Center$320,0001n/a
National Institute on Scientific Teaching Inc$313,633193%
Brigham Young University$238,1433n/a
Boys and Girls Clubs of Greater Washington and Affiliate$200,00021%
The Henrietta Lacks Foundation Inc$150,000187%
Tufts Univ$144,5992n/a
Helen Hay Whitney Foundation$131,66721%
School of Molecular and Theoretical Biology Inc$111,00024%
University of Arizona$100,0003n/a
Iowa State University$94,5842n/a
Prince George's County Public Schools$78,1251n/a
American University$60,00020%
Louisiana State University$60,0002n/a
Wayne State University$60,0002n/a
Oklahoma State University$60,0002n/a
University of Dayton$60,00020%
Clarkson University$60,00020%
Partnership for Undergraduate Life Sciences Education$52,1861n/a
University of Texas at San Antonio$50,0001n/a
Trustees of Tufts College$50,00010%
University of Arkansas Fayetteville$50,0001n/a
Delaware State University Foundation Inc$50,00021%
Northern Illinois University$50,0001n/a
The Foundation for City College$50,0001n/a
The Institute For Cancer Research$50,00020%
University of California Santa Barbara$50,0001n/a
California State University Los Angeles Auxiliary Services Inc$40,00010%
Utah State University$40,0001n/a
Califonia State University East Bay Foundation Inc$30,00010%
University of Georgia Research Foundation Inc$30,00010%
Georgia State University Research Foundation Inc$30,00010%
Rowan University Foundation Inc$30,00010%
State of West Virginia$30,0001n/a
California Polytechnic State University Foundation$30,00010%
Fond Du Lac Tribal & Community College$30,0001n/a
Boyce Thompson Institute for Plant Research Inc$27,50010%
Travel exp pd on behalf of grantees$26,7231n/a
Understanding Interventions Inc$25,7411n/a
New Mexico State University$25,0001n/a
Travel exp pd on behalf of grantees$20,5942n/a
Bennett College$20,00010%
Saint Augustine's University$20,0001n/a
The Children's Hospital of Philadelphia Foundation$20,00010%
Elizabeth City State University$20,0001n/a
New York University$20,00020%
Fayetteville State University$20,0001n/a
Corporation of Gonzaga University$18,03010%
Seton Hill University$14,29710%
Travel Expense paid on behalf of grantees-Longwood Inn$10,3471n/a
Mass General Brigham Incorporated$10,0001n/a
Federation of American Societies for Experimental Biology$10,00010%
The J David Gladstone Institutes$10,00010%
University of Washington Foundation$10,00010%
La Jolla Institute for Immunology$10,0001n/a
University of Chicago$10,00010%
University of Colorado Foundation$10,00010%
Vanderbilt University Medical Center$10,00010%
University of Kentucky$10,0001n/a
University of California Irvine Foundation$10,00010%
University of Hawaii Foundation$10,00010%
Life Sciences Research Foundation$10,00010%
Travel Expense paid on behalf of grantees-AMR Corp$7,4401n/a
Marine Biological Laboratory$6,39410%
University of Miami$5,85510%
Travel Expense paid on behalf of grantees-Southwest Air$5,4971n/a

Plus 3 recipients with no EIN on record ($158k), not named here.

Where it is load-bearing

Howard Hughes Medical Institute supplied at least a quarter of the budget for 4 of its grantees at some point. The chart plots its 163 largest grantees; load-bearing ones sit top left.

25%50%75%100%$1.0M$10M$100Mgrantee revenue →↑ funder's share of their budgetUniversity of Pittsburgh: $6,325,000 over 2y, 0.1% of budgetLoudoun Education Foundation Inc: $6,000,000 over 4y, 92% of budgetVanderbilt University: $5,572,904 over 5y, 0.1% of budgetThe Trustees of Princeton University: $5,078,025 over 6y, 0.1% of budgetThe Research Foundation for The State University of New York: $4,672,266 over 6y, 0.3% of budgetWashington University: $4,578,897 over 8y, 0.0% of budgetThe Salk Institute for Biological Studies: $4,501,455 over 6y, 1.1% of budgetFred Hutchinson Cancer Research Center: $4,380,474 over 5y, 0.7% of budgetMontgomery County Public Schools Educational Foundation Inc: $4,090,000 over 3y, 74% of budgetCold Spring Harbor Laboratory: $3,466,690 over 4y, 0.8% of budgetCalifornia Institute of Technology: $3,283,431 over 5y, 0.1% of budgetAllen Institute: $2,910,000 over 2y, 1.6% of budgetThe Rockefeller University: $2,885,989 over 7y, 0.3% of budgetWilliam Marsh Rice University: $2,580,000 over 4y, 0.2% of budgetLoyola Marymount University: $2,560,000 over 3y, 0.4% of budgetDuke University: $2,483,317 over 5y, 0.0% of budgetNortheastern University: $2,330,000 over 4y, 0.1% of budgetNorthwestern University: $2,194,907 over 5y, 0.0% of budgetThe Jackson Laboratory: $1,842,000 over 3y, 0.2% of budgetJohns Hopkins University: $1,799,181 over 4y, 0.0% of budgetThe Broad Institute Inc: $1,701,714 over 5y, 0.1% of budgetIup Research Institute: $1,695,000 over 3y, 24% of budgetCase Western Reserve University: $1,669,012 over 3y, 0.1% of budgetWhitehead Institute for Biomedical Research: $1,648,377 over 6y, 0.4% of budgetUniversity of Vermont and State Agricultural College Foundation Inc: $1,648,305 over 1y, 3.1% of budgetOregon Health & Science University Foundation: $1,645,681 over 1y, 1.5% of budgetUniversity of California San Francisco Foundation: $1,493,004 over 2y, 0.3% of budgetTrustees of Boston University: $1,375,000 over 4y, 0.0% of budgetDrexel University: $1,315,000 over 3y, 0.1% of budgetIcahn School of Medicine at Mount Sinai: $1,290,000 over 2y, 0.0% of budgetNational Academy of Sciences: $1,228,000 over 3y, 0.2% of budgetUniversity of la Verne: $1,213,065 over 3y, 0.5% of budgetNational University: $1,165,812 over 2y, 0.3% of budgetSt Jude Children's Research Hospital Inc: $1,152,139 over 2y, 0.1% of budgetDana-Farber Cancer Institute Inc: $1,071,671 over 2y, 0.0% of budgetCornell University: $1,071,458 over 3y, 0.0% of budgetSyracuse University: $1,060,000 over 2y, 0.1% of budgetWheaton College: $1,060,000 over 2y, 0.7% of budgetCalifornia State University San Marcos Corporation: $1,060,000 over 2y, 4.7% of budgetVirginia Commonwealth University Foundat: $1,060,000 over 2y, 5.8% of budgetRoosevelt University: $1,060,000 over 2y, 0.7% of budgetLawrence University of Wisconsin: $1,060,000 over 2y, 0.6% of budgetMount Mary University Inc: $1,060,000 over 2y, 2.7% of budgetVassar College: $1,060,000 over 2y, 0.4% of budgetKalamazoo College: $1,060,000 over 2y, 0.8% of budgetWellesley College: $1,060,000 over 2y, 0.4% of budgetMercy University: $1,060,000 over 2y, 0.6% of budgetUniversity of St Thomas: $1,060,000 over 2y, 0.3% of budget

Tap a dot to name the grantee.

How this is measured
Share of budget is the funder’s grant in a year over the grantee’s total revenue that year, at its highest across the years we hold; revenue is from all sources. Only grantees confirmed against their own filings, whose grants do not exceed their revenue, are plotted: the largest 163.

Nonprofits that may fit its grantmaking

Co-funders

Grantmakers whose grantees overlap with this funder’s far more than size alone predicts. Closer means stronger alignment; arcs show where they also fund each other. Here they form a tightly interlocked group: most of these funders back each other's grantees too.

American Chemical SocietyDC66.9× affinity31 shared granteesties to 11 of 11Hover any node to trace its alignments.Compare side by side →

Open a dossier: American Chemical Society · National Collegiate Athletic Association · Folds of Honor Foundation · The Trustees of Columbia University in the City of New York · American Council of Learned Societies · Tulsa Community Foundation · American Heart Association Inc · Yale University · Cornell University · National Collegiate Inventors & Innovators Alliance Inc · Johns Hopkins University · Association of Public and Land-Grant Universities

How this is measured
Affinity is a Gamma-Poisson posterior co-funding rate, re-centered on the typical rate, so thin evidence shrinks toward no signal. Overlap is association, not proof of shared intent.

Compare Howard Hughes Medical Institute with peer funders

About Howard Hughes Medical Institute

How much does Howard Hughes Medical Institute give?
Howard Hughes Medical Institute reported 31 itemized grants totaling $8,823,841, out of $63,319,232 in total grant expense reported on the return in its FY2025 IRS filing. It funded between 44 and 147 organizations a year over FY2018 to FY2024.
What does Howard Hughes Medical Institute fund?
By grant dollars over FY2017 to FY2025, its largest causes are Education (71%), Health (23%), Science & Tech (5%).
Who are Howard Hughes Medical Institute's largest grantees?
By total granted over FY2017 to FY2025: University of California San Francisco ($13M), Regents of the University of California at Berkeley ($11M), Regents Univ of California ($10M).
Does Howard Hughes Medical Institute fund new organizations?
In FY2024, 11% of the organizations it funded were first-time grantees.
Which funders back the same organizations as Howard Hughes Medical Institute?
Its strongest co-funders, measured against what their size predicts, include American Chemical Society, National Collegiate Athletic Association, Folds of Honor Foundation.
Where is Howard Hughes Medical Institute based?
Howard Hughes Medical Institute is based in MD.

On method. Every financial figure here is read from IRS e-file XML, the funder’s own 990/990-PF, and from the multi-year returns of the 302 grantees we resolved, each linked to its source. Grantee outcomes are each organization’s own program-service reporting (Form 990, Part III), read as association with funding, never as caused by it. Low-confidence name matches are suppressed rather than guessed. How we build these →

How this is measured
Each figure carries one of six labels. Filed is what the funder reported on its return. Official is another government record about an organization, such as a federal award or a charity register, joined by name where no shared identifier exists. Resolved is an identity we worked out where the filing named a recipient without an EIN, kept only above a measured confidence threshold. Computed is arithmetic over those, like themes, portfolio clusters and co-funder strength. Context is a statistic about a place rather than about an organization, which is what the need overlay is: it describes the area a grantee’s address sits in, not where its work lands. Inferred is drawn by a model from text, like the partnerships read out of public news and organization websites. Each is labeled where it appears.

Generated from the IRS Form 990 e-file return for fiscal year 2025, released 2025. Filings run roughly 12 to 24 months behind; figures are dated accordingly.

Source object · view filing

Play a game based on Howard Hughes Medical Institute’s filings →

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