Maryland · Nonprofit
Howard Hughes Medical Institute
Howard Hughes Medical Institute (Maryland) receives grants from 1 organization whose IRS filings report $2,434,215 to it, the largest being THE SIMONS FOUNDATION INC ($2,434,215). 1 of them have funded it in more than one year.
- Revenue FY2025
- $2.0B
- Funders on record
- 1
- Grants received
- $2.4M
- Net assets
- $27.6B
What Howard Hughes Medical Institute does
Mission
The mission of the institute has remained constant since its founding in 1953. As its restated articles of incorporation state the primary purpose and objective of the Howard Hughes Medical Institute shall be the promotion of human knowledge by conducting discovery research and science education, principally within fields associated with basic biomedical sciences, and the dissemination and application of that knowledge for the benefit of humanity.
As stated on its FY2025 Form 990.
Programs
Medical research organization activities the hhmi investigator program the Howard Hughes Medical Institute's approach to biomedical research can be summarized in three words: people, not projects. This commitment is reflected in the hhmi investigator program. Rather than awarding research grants, this program employs scientists,providing them with long-term, flexible funding that they may use to pursue their scientific interests. Hhmi believes that scientists of exceptional talent and imagination will make fundamental discoveries of lasting scientific value andthatbenefithuman healthif they are given the resources, time, and freedom to pursue challenging questions. Hhmi investigators receive a seven-year appointment, which isrenewablepending favorable scientific review. Among the more than265 current hhmi investigators, 16 arenobel laureates andnearly150aremembers of the national academy of sciences. Hhmi investigators direct hhmi research laboratorieslocatedon the campuses ofmore than 55hospitals,universities,and other researchinstitutionsthroughout the united states. Since the early 1990s, investigators have been selected through rigorous national competitions. The…
$832,476,143 spentof which $184,008 as grants$4,559,258 earned by the program88% of program spendingScience education, fellowships, and media programs through its science education, fellowships, and media programs, hhmi invests in individuals, initiatives, and media that advance learning and promote success in science across educational and career stages. Science education programs infy25,hhmirefocuseditsscience education effortsaround student-centeredinitiatives.during the 2024-2025 academic year, thescience education alliance (sea)programsupported7,779 students toparticipateinsea-phages, a two-semesterdiscovery basedcoursethatimmerses students in hands-onscientificresearch.biointeractive, a multimedia resource for high school and college-level introductory biology,continued to provide high-quality educational materialsand professional development workshopsat no chargeto biology instructors throughout the country, reachingmore than 70% of high school and college biology classrooms.hhmialsoannounceda new program calledsuccess in science,whichprovides grantsto12institutionsfor implementingprogramsdesigned toincrease undergraduate persistence in science. Fellowship programs founded in 2004, the gilliam fellows program supportsexceptionalbiomedical phd students and their advisorsto…
$112,031,924 spentof which $63,135,224 as grants$49,474 earned by the program12% of program spending
The 2 programs described on its FY2024 Form 990, listed largest first by expense. Program spending in total: $944,508,067.
The organization over time
Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.
Balance sheet
Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2020 to 2021, from $23.8B to $29.3B (+23%).
How it's funded, over time
Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.
0% of Howard Hughes Medical Institute’s revenue is contributions — more earned-revenue than three-quarters of its peers (1% for the typical peer).
Surplus & reserves
Operating surplus or deficit each year, and months of liquidity in hand. 1 of the last 9 reported years ran a deficit.
reserve
Leadership and staff
The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.
Who funds it, year by year
Grant support over time, funder by funder — shade shows the grant size each year.
From the IRS filings of Howard Hughes Medical Institute’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Where its funders are
Howard Hughes Medical Institute draws 100% of its grant income from funders outside Maryland, across 1 state in all.
Funder states come from each funder’s own filing. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Against its field
Howard Hughes Medical Institute runs a healthier operating margin than three-quarters of the 1,241 health nonprofits its size.
this organization peer median middle 50% of peers· 1,241 health nonprofits over $100M, FY2025
Government funding Howard Hughes Medical Institute receives
Grants and contracts to this organization from federal (USASpending) and state checkbooks, reconciled to its EIN. $75 on record.
- REFUNDS - GENERAL $75
Federal grants vs contracts are distinguished; state line items keep their reported category. Matched by name + geography (the BMF), so coverage is partial and precision-first.
Organizations like Howard Hughes Medical Institute
Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.
In Maryland
Nationally
Read directly from this organization’s own Form 990, as neutral context.
Where the money goes
80% of spending goes to programs.
Governance
Footprint & structure
Files a return copy in 6 states
Part of a family of 93 related entities
- Hhmi I LLC · disregarded
- Hhmi II LLC · disregarded
- Hhmi III LLC · disregarded
- Hhmi IV LLC · disregarded
- Hhmi V LLC · disregarded
Screen this organization
A dated, signed PDF of the compliance screen for Howard Hughes Medical Institute: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.
Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf
Questions and answers
- Who funds Howard Hughes Medical Institute?
- Howard Hughes Medical Institute (Maryland) receives grants from 1 organization whose IRS filings report $2,434,215 to it, the largest being THE SIMONS FOUNDATION INC ($2,434,215). 1 of them have funded it in more than one year.
- How many funders does Howard Hughes Medical Institute have?
- IRS filings report 1 organization giving $2,434,215 in grants to Howard Hughes Medical Institute, 1 of which have funded it in more than one year.
- Who is the largest funder of Howard Hughes Medical Institute?
- THE SIMONS FOUNDATION INC is the largest funder on record, with $2,434,215 in grants. The full list of funders is on this page.
- How can an organization like Howard Hughes Medical Institute find more funders?
- Start with the funders already giving here, then look at the foundations that back similar organizations in Maryland. The funding by cause and by state pages list the largest funders for a given area and how to approach them.
These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2017–2025), and the filings of 1 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing