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Massachusetts · Nonprofit

TargetCancer Foundation Inc

TargetCancer Foundation Inc (Massachusetts) receives grants from 23 organizations whose IRS filings report $766,445 to it, the largest being GivenGain Foundation USA ($247,534). 9 of them have funded it in more than one year, and 53% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.

Revenue FY2025
$1.3M
Funders on record
23
Grants received
$766k
Net assets
$1.0M
9/23 repeat funderspeak grant-dependency 45%
01What it does

What TargetCancer Foundation Inc does

Mission

TargetCancer Foundation promotes the development of lifesaving treatment protocols for rare cancers. TargetCancer Foundation directly supports initiatives at the forefront of cancer treatment by funding innovative research, fostering collaborations, and raising awareness among scientists, clinicians, and patients.

As stated on its FY2025 Form 990.

Program

  1. The specific purposes of the Organization are to raise awareness of and support for research into rare cancers, and to directly support patients and families facing rare cancers. This was accomplished in the fiscal year through the ongoing operation of a rare cancer precision medicine clinical trial, and through other programs. In 2020, TargetCancer Foundation launched a rare cancer precision medicine clinical trial called TCF-001 TRACK (Target Rare Cancer Knowledge). TRACK is a 400-patient clinical trial studying genomics and precision medicine in rare cancers, providing patients with critical personalized genomic data about their cancer and treatment recommendations from a panel of field leaders, and also generating rare cancer research data. TRACK is developed, sponsored and managed by TargetCancer Foundation, and is currently over halfway through its enrollment of patients with rare cancers and cancer of unknown primary.In 2024, TargetCancer Foundation held a major scientific meeting- the Think Tank on Advancing Precision Medicine in Rare Cancers. This unique, innovative meeting unites key stakeholders including clinicians, researchers, government, industry, and patients and…

    $508,441 spent
    100% of program spending

The program described on its FY2024 Form 990. Program spending in total: $508,441.

02The organization over time

The organization over time

Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20172017 Revenue 100 ($398k) Expenses 100 ($309k) Net assets 100 ($248k)2018 Revenue 86 ($343k) Expenses 119 ($367k) Net assets 90 ($224k)2019 Revenue 97 ($384k) Expenses 112 ($346k) Net assets 98 ($244k)2020 Revenue 180 ($714k) Expenses 148 ($458k) Net assets 202 ($500k)2021 Revenue 132 ($523k) Expenses 192 ($593k) Net assets 173 ($429k)2022 Revenue 128 ($511k) Expenses 151 ($467k) Net assets 191 ($472k)2023 Revenue 213 ($846k) Expenses 228 ($705k) Net assets 260 ($645k)2024 Revenue 170 ($676k) Expenses 258 ($798k) Net assets 211 ($524k)2025 Revenue 317 ($1.3M) Expenses 271 ($839k) Net assets 410 ($1.0M)
'17'18'19'20'21'22'23'24'25
Revenue (317)Expenses (271)Net assets (410)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2024 to 2025, from $524k to $1.0M (+94%).

$248k
$224k
$244k
$500k
$429k
$472k
$645k
$524k
$1.0M
'17'18'19'20'21'22'23'24'25
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2017
2018
2019
2020
2021
2022
2023
2024
2025
ContributionsProgram revenueInvestmentOther

Government-grant reliance: 2021 7% · 2022 7%. Grants only. Government contracts and fees sit inside program revenue.

104% of TargetCancer Foundation Inc’s revenue is contributions — more reliant on donations than three-quarters of its peers (51% for the typical peer).

This organization
Typical peer · 8,632 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 3 of the last 9 reported years ran a deficit.

$88k
’17
−$24k
’18
$38k
’19
$256k
’20
−$70k
’21
$43k
’22
$141k
’23
−$121k
’24
$423k
’25
14
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Chief executive

James M Palma

Chief Executive Officer

As listed on its FY2025 Form 990.

'17'18'19'20'21'22'23'24'25
Listed131011111111111111
Joined·+0+2+1+1+0+1+0+0
No longer listed·31110100
03Who funds it

Who funds it, year by year

2017 → 2023: the base broadened from 3 funders to 5 funders, grant income rose $29k → $126k.

11 of 23 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 53% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

From the IRS filings of TargetCancer Foundation Inc’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

TargetCancer Foundation Inc leans on a few funders — its largest provides 32% of grant income and the top three 69%; half comes from just 2 funders.

the vertical line marks half of all grant income — 2 funders to its left

98% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund TargetCancer Foundation Inc.

32%
largest funder
69%
top three
~5
effective funders

Largest funder’s share by year: 2017 53% · 2018 55% · 2019 38% · 2020 53% · 2021 96% · 2022 59% · 2023 78% — growing more concentrated.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How long its funders stay

29% of TargetCancer Foundation Inc's funders are still giving 3 years after their first grant; 39% give in more than one year at all.

first grant+1y+2y+3y+4y+5y

Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.

Where its funders are

53% of TargetCancer Foundation Inc's grant income arrives through donor-advised or pass-through sponsors, whose addresses record where the money is held rather than where the donor is. Of the $360k that is directly attributable, 73% of it comes from funders outside Massachusetts, across 8 states.

NH
IL
NY
MA
CA
NC
GA
FL

In-state vs out-of-state, by year

’17
’18
’19
’20
’21
’22
’23
Massachusetts out of state home

Funder states come from each funder’s own filing. $406k arriving through sponsors registered in 10 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

TargetCancer Foundation Inc runs a healthier operating margin than three-quarters of the 5,002 health nonprofits its size.

Operating margin33% · top quartile
Months of reserve14.3mo · top quartile
Revenue growth (annualized)16% · above the median

this organization peer median middle 50% of peers· 5,002 health nonprofits $1M–$10M, FY2025

Organizations like TargetCancer Foundation Inc

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In Massachusetts

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

61% of spending goes to programs.

Program 61%Management 27%Fundraising 13%

Governance

11
board members
82%
independent
✓Conflict-of-interest policy✓Whistleblower policy✓Document retention✓Board reviewed the 990✓Audited financials

Public support

71%

Share of support from the public (Schedule A) — the basis for its public-charity status.

Footprint & structure

Files a return copy in 1 state

MA

Screen this organization

A dated, signed PDF of the compliance screen for TargetCancer Foundation Inc: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds TargetCancer Foundation Inc?
TargetCancer Foundation Inc (Massachusetts) receives grants from 23 organizations whose IRS filings report $766,445 to it, the largest being GivenGain Foundation USA ($247,534). 9 of them have funded it in more than one year, and 53% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
How many funders does TargetCancer Foundation Inc have?
IRS filings report 23 organizations giving $766,445 in grants to TargetCancer Foundation Inc, 9 of which have funded it in more than one year.
Who is the largest funder of TargetCancer Foundation Inc?
GivenGain Foundation USA is the largest funder on record, with $247,534 in grants. The full list of funders is on this page.
How can an organization like TargetCancer Foundation Inc find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in Massachusetts. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2017–2025), and the filings of 23 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 22, 2026. What this page cannot tell you · view filing