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· Public charity

Institute for Advanced Clinical Trials for Children

To function as a nonprofit educational, scientific and research organization to enable and advance pediatric clinical research prescribed by regulation through: (continued on sched.o)

$191k
Granted FY2025still arriving
1
Grants FY2025still arriving
1
States reached
$229k
Largest
01What it funds
01100% classified

What it funded, over time

Every grant placed by its stated purpose and the recipient’s mission, by year, FY2018 to 2025.

Health$1.5MEducation$115kHuman Services$8kScience & Tech$8k
02FY2025 · 1 grant

Where the money goes

Grants by size, and the largest recipients.

$229,392
Median grant
1
States reached
$0
Total assets
Largest grants
RecipientAmount
CRITICAL PATH INSTITUTE$229,392
02The need
03

Does the money reach high-need areas?

Each grant placed by the hardship in its grantee’s ZIP, against the area’s typical level.

show:

Dollar for dollar, its grants (FY18–25) land where the poverty rate runs at 15%, against an area that typically sits at 11%. 95% of its dollars go to grantees based in above-average-need neighborhoods. Most of its grants land in higher-need ZIPs.

area typical 11%ARIZONA ALLERGY & IMMUNOLOGY RESEARCH LLC: $8k → 11%CRITICAL PATH INSTITUTE: $229k → 15%MASSACHUSETTS GENERAL HOSPITAL: $8k → 16%ALIVATION RESEARCH LLC: $8k → 13%GILLETTE CHILDREN'S SPECIALTY HEALTHCARE: $8k → 14%UNIVERSITY OF PITTSBURG: $8k → 11%CHILDREN'S HOSPITAL OF PHILADELPHIA RESEARCH INSTITUTE: $75k → 22%CHILDREN'S HOSPITAL OF ORANGE COUNTY: $8k → 10%THE REGENTS OF THE UNIVERSITY OF CALIFORNIA: $8k → 14%REGENTS OF THE UNIVERSITY OF CALIFORNIA DAVIS: $8k → 16%THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH: $8k → 6%NYU GROSSMAN SCHOOL OF MEDICINE: $8k → 17%MONTEFIORE MEDICAL CENTER: $8k → 28%ARKANSAS CHILDREN'S RESEARCH INSTITUTE: $8k → 14%UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO: $8k → 16%BAYLOR COLLEGE OF MEDICINE: $8k → 16%DRISCOLL CHILDREN'S HOSPITAL: $10k → 17%MEDICAL UNIVERSITY OF SOUTH CAROLINA: $8k → 12%CHILDREN'S NATIONAL MEDICAL CENTER: $93k → 14%THE NEMOURS FOUNDATION: $30k → 14%NICKLAUS CHILDREN'S HOSPITAL: $8k → 15%STATE UNIVERSITY OF IOWA: $8k → 15%WILLIAM BEAUMONT HOSPITAL: $8k → 8%SPECTRUM HEALTH SYSTEM: $8k → 11%REGENTS OF THE UNIVERSITY OF MICHIGAN: $8k → 14%CHILDREN'S MERCY KANSAS CITY: $55k → 15%RHODE ISLAND HOSPITAL: $8k → 14%ASPEN CLINICAL RESEARCH: $8k → 8%CHILDREN'S HEALTHCARE OF ATLANTA: $8k → 13%CHILDREN'S HOSPITAL OF COLORADO: $8k → 10%AKRON CHILDREN'S HOSPITAL: $8k → 13%CHILDREN'S NATIONAL MEDICAL CENTER CINCINNATI: $111k → 16%WEST VIRGINIA UNIVERSITY: $8k → 19%ANN & ROBERT H LURIE CHILDREN'S HOSPITAL OF CHICAGO: $48k → 14%CRITICAL PATH INSTITUTE: $33k → 15%CHILDREN'S HOSPITAL OF PHILADELPHIA: $55k → 22%CHILDREN'S NATIONAL MEDICAL CENTER: $62k → 14%CHILDREN'S HOSPITAL MEDICAL CENTER CINCINNATI: $78k → 16%CRITICAL PATH INSTITUTE: $14k → 15%CHILDREN'S HOSPITAL OF PHILADELPHIA RESEARCH INSTITUTE: $23k → 22%CHILDREN'S NATIONAL MEDICAL CENTER: $62k → 14%CHILDREN'S NATIONAL MEDICAL CENTER CINCINNATI: $64k → 16%CRITICAL PATH INSTITUTE: $12k → 15%CHILDREN'S NATIONAL MEDICAL CENTER: $34k → 14%CHILDREN'S NATIONAL MEDICAL CENTER CINCINNATI: $41k → 16%CRITICAL PATH INSTITUTE: $8k → 15%CHILDREN'S NATIONAL MEDICAL CENTER: $19k → 14%CHILDREN'S NATIONAL MEDICAL CENTER CINCINNATI: $37k → 16%0%20%40%50%more need →
grant to an above-average-need area below average· circle size = grant amount
How this is measured
Matched: human-services grants are those whose grantee’s IRS cause code is Human Services. Placed by people below the poverty line in the grantee’s ZIP, averaged from the tracts in that ZIP.

Which US states its grants reach

ME
ID
MN
IL
WI
MI
NY
MA
IA
OH
PA
NJ
RI
CA
UT
CO
NE
MO
KY
WV
VA
AZ
NM
AR
TN
NC
SC
DC
LA
MS
GA
TX
FL
How this is measured
US grants placed by each grantee’s ZIP, which can differ from where services are delivered. Need from public data (U.S. Census/ACS, CDC PLACES, Eviction Lab, USDA), shown as context about the area, never attributed to the funder’s giving.
03Its grantees
repeat funding

Who it funds again

Organizations funded in more than one year, against those funded once.

70%of every dollar goes to organizations it has funded before.
$1.1M · 5 repeat orgs$488k to everyone else

Grantees it renews have grown median revenue +72% since the first grant, against +36% for those funded once.

5 repeat relationships: 1 still active in FY2025, 4 since wound down.

How the two cohorts compare

Re-uppedFunded once

Organizations

5
56

Total granted

$1.1M
$488k

Median revenue growth · since first grant

+72%
+36%

Still filing today

100%
63%

New vs renewed · share of each year

In FY2025, 100% of grant dollars renewed an existing relationship; $0 went to new ones.

50%100%’18’19’20’21’22’23’25
RenewedFirst-time

Where new relationships form · theme of each grantee’s first grant

’18’19’20’21’22’23’25
HealthEducationOther
How this is measured
First-time means a grantee’s first year in the filing window; renewed means funded in an earlier year too. The renewed share climbs naturally as a portfolio matures, so the signal is a year that bucks it (a wave of new grantees). The earliest year is left-censored: relationships that predate the data read as new. Theme is the grantee’s IRS cause.

Backed again, and grew

  • TC
    The Childrens Hospital
    5× · 2018–2022 · $330k · revenue +111%
  • CP
    CRITICAL PATH INSTITUTE
    6× · 2018–2025 · $302k · revenue +206%
  • CN
    CHILDREN'S NATIONAL
    5× · 2018–2022 · $269k · revenue +38%

Funded once

  • Ann & Robert H Lurie Children's Hospital of Chicago
    one grant, 2023 · $48k · revenue +4%
  • TN
    THE NEMOURS FOUNDATIONgraduated
    one grant, 2019 · $30k · revenue +54%
  • DC
    Driscoll Children's Hospitalgraduated
    one grant, 2023 · $10k · revenue +44%
How this is measured

Repeat means funded in two or more distinct years. Growth and survival are read from each grantee’s own subsequent IRS filings.

04Its field

Closest unfunded matches

The nonprofits that most resemble its grantees but are not funded by it, scored along the direction from the rest of the field toward the portfolio. A resemblance in what they say they do, not a recommendation.

1
Children's Hospital Corporation

Provider of pediatric healthcare, education, research & community service

Health
2
Rush University Medical Center

The mission of Rush is to improve the health of the individuals and diverse communities we serve through the integration of outstanding patient care, education, research and community partnerships.

Health
3
Children's Health Care

We champion the health needs of children and families. we are committed to improving children's health by providing the highest-quality, family centered care, advanced through research and education.

Health
4
Methodist Healthcare-Memphis Hospitals

Methodist le bonheur healthcare, in partnership with its medical staffs, will collaborate with patients and their families to be the leader in providing high quality, cost-effective patient-and family-centered care. services will be…

Health
5
East Tennessee Children's Hospital Association Inc

East tennessee children's hospital is a free-standing, independent, not-for-profit pediatric health care system which serves the east tennessee region. children's hospital is certified by the state of tennessee as a comprehensive regional…

Health
6
Mass General Brigham Incorporated & Affiliates Group Return

Mass general brigham incorporated is developing an integrated health care delivery system throughout the region that offers patients a continuum of coordinated, high-quality care.

Health
7
Johns Hopkins Health System Corporation

Johns hopkins health system corporation provides centralized management of a multi-hospital healthcare system. it is a key component of johns hopkins medicine, a collaboration with the johns hopkins university school of medicine.

Health
8
University of Minnesota Physicians

University of minnesota physicians serves as the integrated group practice for the university of minnesota medical school full-time faculty to provide the highest quality healthcare to patients and their families.university of minnesota…

Health
9
Children's Hospital of Chicago Medical Center

We are dedicated to the health and well-being of all children. as the pediatric teaching facility for the northwestern university feinberg school of medicine, this commitment drives us to be a leader in: -pediatric health care delivery…

Health
10
Thomas Jefferson University

Thomas jefferson university ("tju") is a comprehensive university with preeminence in transdisciplinary, experiential professional education, research and discovery, delivering exceptional value for the 21st century students with…

Education
11
Children's Hospital & Research Center At Oakland

The mission of children's hospital & research center at oakland is to protect and advance the health and well-being of children through clinical care, teaching and research.

Health
12
Loyola University Medical Center

We, loyola university health system and trinity health, serve together in the spirit of the gospel as a compassionate and transforming healing presence within our communities.lumc is a member of loyola university health system and trinity…

Health
How this is measured
The grantee most central to the portfolio’s shape is Children's Hospital Medical Center; the most unlike its peers is Critical Path Institute. Resemblance is measured on each organization’s own IRS 990 mission text; it reflects how work is described, not its quality or impact.
04the grantee network

42 grantees tracked through their own filings, 2017–2025.

Each grant beside the grantee’s revenue from every source, year by year.

How this is measured

Counted here: distinct organizations funded across 2017 to 2025, not grant rows in a single year, so this will not match the grant count on the cover. 42 of the 61 grantees resolved in that span have returns of their own we could reconcile.

Each grantee is resolved to its own IRS returns. Association, dated; never a causal claim.

0
Load-bearing (≥25% of a budget)
0
Early backer (in before they grew)
40/42
Grantees still filing
38/42
Grew since first funded

Where the money sits, by cause and then by grantee

The Childrens Hospital: $330,251 · HealthThe Childrens HospitalCRITICAL PATH INSTITUTE: $302,114 · HealthCRITICAL PATH INSTITUTECHILDREN'S NATIONAL: $269,477 · HealthCHILDREN'S NATIONALTHE CHILDREN'S HOSPITAL OF PHILADELPHIA: $159,817 · HealthTHE CHILDREN'S HOSPITAL OF PHILADELPHIAThe Children's Mercy Hospital: $62,697 · HealthAnn & Robert H Lurie Children's Hospital of Chicago: $47,740 · Health+26 more: $220,000 · Health+26 moreUNIVERSITY OF NEW MEXICO: $10,000 · OtherUNIVERSITY…UNIVERSITY OF CALIFORNIA DAVIS: $7,500 · OtherCENTER FOR EMOTIONAL FITNESS: $7,500 · OtherPHI CHI MEDICAL FRATERNITY INC: $7,500 · OtherTHE UNIV OF TX HEALTH SCIENCE CTR OF SA: $7,500 · OtherState University of Iowa: $7,500 · OtherASPEN CLINICAL RESEARCH: $7,500 · OtherARIZONA ALLERGY & IMMUNOLOGY RESEARCH LLC: $7,500 · OtherREGENTS OF THE UNIVERSITY OF MICHIGAN: $7,500 · OtherUNIVERSITY HOSPITALS HEALTH SYSTEM INC: $7,500 · OtherRutgers the State University: $7,500 · OtherUNIVERSITY OF MISS MEDICAL CENTER: $7,500 · OtherREGENTS UNIV OF CALIFORNIA: $7,500 · OtherUNIVERSITY OF MINNESOTA: $7,500 · OtherREGENTS OF THE UNIVERSITY OF CALIFORNIA AT IRVINE: $7,500 · OtherSTATE OF WEST VIRGINIA: $7,500 · OtherMASS GENERAL BRIGHAM INCORPORATED: $7,500 · OtherALIVATION RESEARCH LLC: $7,500 · OtherUNIVERSITY OF FLORIDA: $7,500 · OtherARKANSAS CHILDREN'S RESEARCH INSTITUTE: $7,500 · OtherUniversity of Louisville Research Foundation: $7,500 · EducationJOHNS HOPKINS UNIVERSITY: $7,500 · EducationGEORGETOWN UNIVERSITY: $7,500 · EducationWAKE FOREST UNIVERSITY HEALTH SCIENCES: $7,500 · EducationUniversity of Miami: $7,500 · EducationUNIVERSITY OF PITTSBURGH: $7,500 · EducationNew York University: $7,500 · EducationBaylor College of Medicine: $7,500 · EducationTHE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND: $7,500 · Education
Health$1,392,096Other$152,500Education$67,500

Each grantee by its size and the funder’s share of it; top left is load-bearing

25%50%75%100%$100Mgrantee revenue →↑ funder's share of their budgetThe Childrens Hospital: $330,251 over 5y, 0.1% of budgetCRITICAL PATH INSTITUTE: $302,114 over 6y, 0.5% of budgetCHILDREN'S NATIONAL: $269,477 over 5y, 2.7% of budgetTHE CHILDREN'S HOSPITAL OF PHILADELPHIA: $159,817 over 4y, 0.0% of budgetThe Children's Mercy Hospital: $62,697 over 2y, 0.0% of budgetAnn & Robert H Lurie Children's Hospital of Chicago: $47,740 over 1y, 0.0% of budgetTHE NEMOURS FOUNDATION: $30,000 over 1y, 0.0% of budgetDriscoll Children's Hospital: $10,000 over 1y, 0.0% of budgetLe Bonheur Children's Hospital Foundation: $7,500 over 1y, 0.0% of budgetVariety Children's Hospital: $7,500 over 1y, 0.0% of budgetGillette Children's Specialty Healthcare: $7,500 over 1y, 0.0% of budgetCHILDREN'S HOSPITAL OF ORANGE COUNTY: $7,500 over 1y, 0.0% of budgetCOREWELL HEALTH: $7,500 over 1y, 0.0% of budgetBAYSTATE MEDICAL CENTER INC: $7,500 over 1y, 0.0% of budgetCHILDREN'S HOSPITAL INC: $7,500 over 1y, 0.0% of budgetCHILDREN'S HOSPITAL MEDICAL CENTER OF AKRON: $7,500 over 1y, 0.0% of budgetRhode Island Hospital: $7,500 over 1y, 0.0% of budgetCHILDREN'S RESEARCH INSTITUTE: $7,500 over 1y, 0.0% of budgetCHILDREN'S HEALTHCARE OF ATLANTA INC: $7,500 over 1y, 0.0% of budgetUniversity of Louisville Research Foundation: $7,500 over 1y, 0.0% of budgetSt Luke's Regional Medical Center Ltd: $7,500 over 1y, 0.0% of budgetMaineHealth: $7,500 over 1y, 0.0% of budgetJOHNS HOPKINS UNIVERSITY: $7,500 over 1y, 0.0% of budgetGEORGETOWN UNIVERSITY: $7,500 over 1y, 0.0% of budgetWAKE FOREST UNIVERSITY HEALTH SCIENCES: $7,500 over 1y, 0.0% of budgetTHE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH: $7,500 over 1y, 0.0% of budgetChildren's Hospital Colorado: $7,500 over 1y, 0.0% of budgetADVOCATE HEALTH AND HOSPITALS CORP: $7,500 over 1y, 0.0% of budgetUniversity of Miami: $7,500 over 1y, 0.0% of budgetCHILDREN'S HOSPITAL MEDICAL CENTER: $7,500 over 1y, 0.0% of budgetPrisma Health-Midlands: $7,500 over 1y, 0.0% of budgetTHE CLEVELAND CLINIC FOUNDATION: $7,500 over 1y, 0.0% of budgetUNIVERSITY OF PITTSBURGH: $7,500 over 1y, 0.0% of budgetNew York University: $7,500 over 1y, 0.0% of budgetWILLIAM BEAUMONT HOSPITAL: $7,500 over 1y, 0.0% of budgetChildren's Hospital and Healthcare Services Foundation: $7,500 over 1y, 0.0% of budgetBaylor College of Medicine: $7,500 over 1y, 0.0% of budgetMONTEFIORE MEDICAL CENTER: $7,500 over 1y, 0.0% of budgetCHILDREN'S HOSPITAL OF WISCONSIN INC: $7,500 over 1y, 0.0% of budgetTHE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND: $7,500 over 1y, 0.0% of budgetARKANSAS CHILDREN'S RESEARCH INSTITUTE: $7,500 over 1y, 0.0% of budget
Grantee by grantee: a decade per organization, before and after funding

A decade per grantee: revenue shaded, grants as bars, all rows on one timeline.

Co-funders

Grantmakers whose grantees overlap with this funder’s far more than size alone predicts. Closer means stronger alignment; arcs show where they also fund each other. Here they form a tightly interlocked group: most of these funders back each other's grantees too.

The Children's Oncology Group Foundation IncPA34.7× affinity14 shared granteesties to 11 of 11Hover any node to trace its alignments.Compare side by side →

Open a dossier: The Children's Oncology Group Foundation Inc · Cystic Fibrosis Foundation · The Children's Hospital of Philadelphia · Public Health Institute · Muscular Dystrophy Association Inc · American Heart Association Inc · St Baldrick's Foundation Inc · Vanderbilt University Medical Center · Johns Hopkins University · Yale University · Reach Out and Read Inc · The Trustees of Columbia University in the City of New York

How this is measured
Affinity is a Gamma-Poisson posterior co-funding rate, re-centered on the typical rate, so thin evidence shrinks toward no signal. Overlap is association, not proof of shared intent.

How much its grantees rely on government

Each dot is one organization Institute for Advanced Clinical Trials for Children funds: left to right is the share of its income from government, bottom to top the share from Institute for Advanced Clinical Trials for Children. Bigger dots raise more.

2024
’20’21’22’23’24’25
no gov · 00%0%1%3%5%funder's share of their income ↑0%25%50%75%100%share of the org’s income from government →median 5%
  • Johns Hopkins University: 12% of income from government
  • Baystate Medical Center Inc: 9% of income from government
  • University of Miami: 5% of income from government
  • Variety Children's Hospital: 1% of income from government
  • The Nemours Foundation: 0% of income from government
no gov moneyreceives it· size = income
0get no government money at all
5report government grants on their 990 we could not trace to a source (not plotted)
0rely on government for over half their income
typical government reliance, FY20–25
How this is measured
Government income is each org’s traced federal awards (USASpending grants and contracts) plus state payments (open checkbooks) as a share of its total revenue (IRS Form 990); the self-reported government-grant line (990 line 1e) is carried for cross-check: a grantee that reports government grants we could not trace to a source is left off the chart rather than shown as receiving none. An association, not a claim that a grant caused the public funding. Coverage is precision-first, a floor rather than a census; state records exist for 9 states, so a grantee outside them shows no state figure (dimmed) rather than a false zero. Federal award amounts are obligations, which can span years, so a single-year share is indicative. 990 filings lag 12 to 24 months.

On method. Every financial figure here is read from IRS e-file XML, the funder’s own 990/990-PF, and from the multi-year returns of the 61 grantees we resolved, each linked to its source. Grantee outcomes are each organization’s own program-service reporting (Form 990, Part III), read as association with funding, never as caused by it. Low-confidence name matches are suppressed rather than guessed. How we build these →

How this is measured
Each figure carries one of six labels. Filed is what the funder reported on its return. Official is another government record about an organization, such as a federal award or a charity register, joined by name where no shared identifier exists. Resolved is an identity we worked out where the filing named a recipient without an EIN, kept only above a measured confidence threshold. Computed is arithmetic over those, like themes, portfolio clusters and co-funder strength. Context is a statistic about a place rather than about an organization, which is what the need overlay is: it describes the area a grantee’s address sits in, not where its work lands. Inferred is drawn by a model from text, like the partnerships read out of public news and organization websites. Each is labeled where it appears.

Generated from the IRS Form 990 e-file return for fiscal year 2025, released 2025. Filings run roughly 12 to 24 months behind; figures are dated accordingly.

Source object · view filing

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