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Critical Path Institute at a glanceMostly funded, not a grantmaker: see who funds it →

· Public charity

Critical Path Institute

The CRITICAL PATH INSTITUTE is a catalyst in the development of new approaches that advance medical innovation and regulatory science.

$5.2M
Granted FY2025still arriving
17
Grants FY2025still arriving
12
States reached
$1.3M
Largest
01What it fundsRead
02The needRead
03Its granteesRead
04Its fieldRead
05Through PlinthRead
01What it funds
01100% classified

What it funded, over time

Every grant placed by its stated purpose and the recipient’s mission, by year, FY2017 to 2025.

Health$20MEducation$4.8MRecreation & Sports$1.3MScience & Tech$635kReligion$50kCommunity Improvement$27kArts & Culture$24k
02FY2025 · 17 grants

Where the money goes

Grants by size, and the largest recipients.

How this is measured
The 17 grants below total $3,758,536, the rows itemized in this filing. The $5,186,032 headline is the total grant expense on the return; the other $1,427,496 is giving the schedule does not break out (grants under the $5,000 itemization floor, grants to individuals, grants on other schedules). Every figure below describes the itemized rows only.

By grant size · FY2025

  • $10k–50k1 grant · $23k
  • $50k–250k13 grants · $1.7M
  • $250k+3 grants · $2.0M
$127,093
Median grant
12
States reached
$38M
Total assets
Largest grants
RecipientAmount
NATIONAL ORGANIZATION FOR RARE DISORDERS$1,319,385
NORTHWESTERN UNIVERSITY$381,946
UNIVERSITY OF CALIFORNIA$347,500
SEATTLE CHILDREN'S HOSPITAL$234,728
WAKE FOREST UNIVERSITY$215,717
YALE UNIVERSITY$172,778
UNIVERSITY OF PITTSBURGH$145,000
WASHINGTON UNIVERSITY$140,000
UNIVERSITY HOSPITAL CLEVELAND MEDICAL CTR$127,093
BIOAGILYTIX LABS$111,767
HMH HOSPITALS CORP$109,798
UNIVERSITY OF ARIZONA$102,500
BANNER HEALTH$97,488
PENNSYLVANIA STATE UNIVERSITY$92,500
ILLUMINA$77,336
02The need
03

Does the money reach high-need areas?

Each grant placed by the hardship in its grantee’s ZIP, against the area’s typical level.

show:

Dollar for dollar, its grants (FY17–25) land where the poverty rate runs at 11%, against an area that typically sits at 10%. 56% of its dollars go to grantees based in above-average-need neighborhoods. Most of its grants land in higher-need ZIPs.

area typical 10%THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE: $395k → 11%NATIONAL ORGANIZATION FOR RARE DISORDERS (NORD): $2.0M → 7%TUFTS MEDICAL CENTER INC: $102k → 16%MAYO CLINIC: $132k → 9%PENNSYLVANIA STATE UNIVERSITY: $95k → 12%ILLUMINA: $77k → 11%UNIVERSITY OF ROCHESTER: $187k → 14%MYRIAD RBM INC: $27k → 10%BAYLOR RESEARCH INSTITUTE: $1.3M → 14%JAEB CENTER FOR HEALTH RESEARCH: $84k → 13%THE REGENTS OF THE UNIV OF MICHIGAN: $184k → 14%WASHINGTON UNIVERSITY: $140k → 21%BIOAGILYTIX LABS: $112k → 11%RADYUS RESEARCH: $32k → 13%EMORY UNIVERSITY: $525k → 14%UNIVERSITY HOSPITAL CLEVELAND MEDICAL CTR: $127k → 17%NORTHWESTERN UNIVERSITY: $382k → 14%RUTGERS THE STATE UNIVERSITY: $82k → 8%EDETEK INC: $168k → 11%HMH HOSPITALS CORP: $110k → 16%JOHN HOPKINS UNIVERSITY: $32k → 19%THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE: $294k → 11%NATIONAL ORGANIZATION FOR RARE DISORDERS (NORD): $1.6M → 7%TUFTS MEDICAL CENTER INC: $86k → 16%PENNSYLVANIA STATE UNIVERSITY: $93k → 12%UNIVERSITY OF ROCHESTER: $90k → 14%UNIVERSITY OF TEXAS: $60k → 10%BAYLOR RESEARCH INSTITUTE: $400k → 14%JAEB CENTER FOR HEALTH RESEARCH: $28k → 13%EMORY UNIVERSITY: $314k → 14%NORTHWESTERN UNIVERSITY: $179k → 14%INSTITUTE FOR ADVANCED CLINICAL TRIALS FOR CHILDREN: $138k → 8%THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE: $35k → 11%NATIONAL ORGANIZATION FOR RARE DISORDERS (NORD): $1.5M → 7%TUFTS MEDICAL CENTER INC: $28k → 16%BAYLOR RESEARCH INSTITUTE: $1.1M → 14%EMORY UNIVERSITY: $161k → 14%NORTHWESTERN UNIVERSITY: $54k → 14%INSTITUTE FOR ADVANCED CLINICAL TRIALS FOR CHILDREN: $78k → 8%BANNER HEALTH: $97k → 11%NATIONAL ORGANIZATION FOR RARE DISORDERS: $1.3M → 7%BAYLOR RESEARCH INSTITUTE: $996k → 14%NORTHWESTERN UNIVERSITY: $45k → 14%ADELPHI VALUES: $50k → 16%NORTHWESTERN UNIVERSITY: $266k → 14%NORTHWESTERN UNIVERSITY: $163k → 14%FOUNDATION FOR THE NATIONAL INSTITUTES OF HEALTH INC: $45k → 8%NORTHWESTERN UNIVERSITY: $77k → 14%0%20%40%50%more need →
grant to an above-average-need area below average· circle size = grant amount
How this is measured
Matched: human-services grants are those whose grantee’s IRS cause code is Human Services. Placed by people below the poverty line in the grantee’s ZIP, averaged from the tracts in that ZIP.

Which US states its grants reach

WA
MN
IL
MI
NY
MA
OH
PA
NJ
CT
CA
UT
CO
MO
MD
AZ
NC
GA
TX
FL

Grants abroad, by region: $1.4M on the FY2025 return

Schedule F, as filed: 2 regions. The IRS asks for region and purpose, not the recipient, so no country or grantee can be named here.

Europe (including Iceland and Greenland)$826k · 58% · 2 grants

Stated purpose: SUBAWARD

East Asia and the Pacific$601k · 42% · 2 grants

Stated purpose: SUBAWARD

How this is measured
US grants placed by each grantee’s ZIP, which can differ from where services are delivered. Need from public data (U.S. Census/ACS, CDC PLACES, Eviction Lab, USDA), shown as context about the area, never attributed to the funder’s giving. Grants abroad on Schedule F are filed by region, purpose and amount with no recipient name, so they are shown by region and cannot be placed on the country map or matched to a grantee.
03Its grantees
repeat funding

Who it funds again

Organizations funded in more than one year, against those funded once.

94%of every dollar goes to organizations it has funded before.
$25M · 20 repeat orgs$1.6M to everyone else

20 repeat relationships: 6 still active in FY2025, 14 since wound down; 10 grantees were first funded in FY2025 (too recent to call).

How the two cohorts compare

Re-uppedFunded once

Organizations

20
9

Total granted

$25M
$414k

Still filing today

65%
0%

New vs renewed · share of each year

In FY2025, 67% of grant dollars renewed an existing relationship; $1.2M went to new ones.

50%100%’17’18’19’20’21’22’23’24’25
RenewedFirst-time

Where new relationships form · theme of each grantee’s first grant

’17’18’19’20’21’22’23’24’25
HealthEducationRecreation & SportsOther
How this is measured
First-time means a grantee’s first year in the filing window; renewed means funded in an earlier year too. The renewed share climbs naturally as a portfolio matures, so the signal is a year that bucks it (a wave of new grantees). The earliest year is left-censored: relationships that predate the data read as new. Theme is the grantee’s IRS cause.

Backed again, and grew

  • BR
    Baylor Research Institute
    4× · 2017–2020 · $3.8M · revenue +33%
  • SO
    SOCIETY OF CRITICAL CARE MEDICINE
    3× · 2022–2024 · $2.7M · revenue +9%
  • JOHNS HOPKINS UNIVERSITY
    4× · 2017–2024 · $1.3M · revenue +64%

Funded once

  • EI
    EDETEK INC
    one grant, 2021 · $168k
  • RT
    RUTGERS THE STATE UNIVERSITY
    one grant, 2022 · $82k
  • AV
    ADELPHI VALUES
    one grant, 2021 · $50k
How this is measured

Repeat means funded in two or more distinct years. Growth and survival are read from each grantee’s own subsequent IRS filings.

04Its field

Closest unfunded matches

The nonprofits that most resemble its grantees but are not funded by it, scored along the direction from the rest of the field toward the portfolio. A resemblance in what they say they do, not a recommendation.

1
Fred Hutchinson Cancer Center

Fred hutch cancer center ("fred hutch") unites innovative research and compassionate care to prevent and eliminate cancer and infectious disease. continued on schedule o

Health
2
The Johns Hopkins Hospital

For more than 125 years, the mission of the johns hopkins hospital has been to lead the world in the diagnosis and treatment of disease and to train tomorrow's great physicians, nurses and scientists. above all, we aim to provide the…

Health
3
University of Minnesota Physicians

University of minnesota physicians serves as the integrated group practice for the university of minnesota medical school full-time faculty to provide the highest quality healthcare to patients and their families.university of minnesota…

Health
4
New York University

Nyu is a private university with approximately 60,000 matriculating students in 20 schools and institutes. nyu's primary missions are education, research and scholarship, and patient care.

Education
5
Rush University Medical Center

The mission of Rush is to improve the health of the individuals and diverse communities we serve through the integration of outstanding patient care, education, research and community partnerships.

Health
6
Drexel University

Drexel university fulfills its founder's vision of preparing each new generation of students for productive professional and civic lives while also focusing its collective expertise on solving society's greatest problems. drexel is an…

Education
7
Truman Medical Center Incorporated

University health is an academic health center providing accessible, state-of-the-art quality healthcare to our community regardless of the ability to pay.

Health
8
Mass General Brigham Incorporated & Affiliates Group Return

Mass general brigham incorporated is developing an integrated health care delivery system throughout the region that offers patients a continuum of coordinated, high-quality care.

Health
9
Memorial Sloan-Kettering Cancer Center

Leadership in the prevention, treatment, and cure of cancer through excellence, vision and cost effectiveness in patient care, outreach programs, research, and education.

Health
10
Albany College of Pharmacy and Health Sciences

We educate the next generation of leaders to improve the health of our society.

Education
11
New York Genome Center Inc

Operate a state-of-the-art, world-class genomic research center that creates and uses advanced genomics to understand the genetic basis of disease. for more information, see schedule o.

Health
12
Rhode Island Hospital

As a founding hospital in the brown university health system, rih is committed to its mission: delivering health with care.

Health
How this is measured
The grantee most central to the portfolio’s shape is Institute for Advanced Clinical Trials for Children; the most unlike its peers is Foundation for the National Institutes of Health Inc. Resemblance is measured on each organization’s own IRS 990 mission text; it reflects how work is described, not its quality or impact.
04the grantee network

20 grantees tracked through their own filings, 2017–2025.

Each grant beside the grantee’s revenue from every source, year by year.

How this is measured

Counted here: distinct organizations funded across 2017 to 2025, not grant rows in a single year, so this will not match the grant count on the cover. 20 of the 41 grantees resolved in that span have returns of their own we could reconcile.

Each grantee is resolved to its own IRS returns. Association, dated; never a causal claim.

0
Load-bearing (≥25% of a budget)
2
Early backer (in before they grew)
19/20
Grantees still filing
14/20
Grew since first funded

Where the money sits, by cause and then by grantee

NATIONAL ORGANIZATION FOR RARE DISORDERS INC: $9,187,663 · OtherNATIONAL ORGANIZATION FOR RARE DISORDERS INCUNIVERSITY OF CALIFORNIA SAN FRANCISCO: $1,972,211 · OtherUNIVERSITY OF CALIFORNIA SAN FRANCISCO+22 more: $2,680,274 · Other+22 moreBaylor Research Institute: $3,778,873 · HealthBaylor Research InstituteSOCIETY OF CRITICAL CARE MEDICINE: $2,693,001 · HealthSOCIETY OF CRITICAL CARE MEDICINETHE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE: $723,538 · HealthTHE TRANSLATIONAL GENOMICS RESEARCH…CLINICAL DATA INTERCHANGE STANDARDS CONSORTIUM INC: $430,346 · Health+5 more: $749,092 · Health+5 moreJOHNS HOPKINS UNIVERSITY: $1,277,141 · EducationJOHNS HOPKINS U…Emory University: $1,000,000 · EducationEmory Universit…Yale University: $515,678 · EducationYale UniversityUNIVERSITY OF ROCHESTER: $286,258 · EducationUNIVERSITY OF R…UNIVERSITY OF PITTSBURGH: $237,500 · EducationUNIVERSITY OF P…WAKE FOREST UNIVERSITY HEALTH SCIENCES: $215,717 · EducationWAKE FOREST UNI…WASHINGTON UNIVERSITY: $140,000 · EducationNorthwestern University: $1,166,106 · Recreation & Sports
Other$13,840,148Health$8,374,850Education$3,672,294Recreation & Sports$1,166,106

Each grantee by its size and the funder’s share of it; top left is load-bearing

25%50%75%100%$10M$100Mgrantee revenue →↑ funder's share of their budgetNATIONAL ORGANIZATION FOR RARE DISORDERS INC: $9,187,663 over 6y, 4.8% of budgetBaylor Research Institute: $3,778,873 over 4y, 2.0% of budgetSOCIETY OF CRITICAL CARE MEDICINE: $2,693,001 over 3y, 4.2% of budgetJOHNS HOPKINS UNIVERSITY: $1,277,141 over 4y, 0.0% of budgetNorthwestern University: $1,166,106 over 7y, 0.0% of budgetEmory University: $1,000,000 over 3y, 0.0% of budgetTHE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE: $723,538 over 3y, 0.5% of budgetYale University: $515,678 over 3y, 0.0% of budgetCLINICAL DATA INTERCHANGE STANDARDS CONSORTIUM INC: $430,346 over 3y, 2.9% of budgetUNIVERSITY OF ROCHESTER: $286,258 over 3y, 0.0% of budgetINSTITUTE FOR ADVANCED CLINICAL TRIALS FOR CHILDREN: $250,333 over 4y, 5.3% of budgetMAYO CLINIC: $250,000 over 2y, 0.0% of budgetUNIVERSITY OF PITTSBURGH: $237,500 over 2y, 0.0% of budgetSEATTLE CHILDREN'S HOSPITAL: $234,728 over 1y, 0.0% of budgetWASHINGTON UNIVERSITY: $140,000 over 1y, 0.0% of budgetJAEB CENTER FOR HEALTH RESEARCH FOUNDATION INC: $126,734 over 3y, 0.3% of budgetFoundation for the National Institutes of Health Inc: $57,078 over 2y, 0.1% of budget
Grantee by grantee: a decade per organization, before and after funding

A decade per grantee: revenue shaded, grants as bars, all rows on one timeline.

  • Who funds NATIONAL ORGANIZATION FOR RARE DISORDERS INC ↗
  • Who funds Baylor Research Institute ↗
  • Who funds SOCIETY OF CRITICAL CARE MEDICINE ↗
  • Who funds JOHNS HOPKINS UNIVERSITY ↗
  • Who funds Northwestern University ↗
  • Who funds Emory University ↗
  • Who funds THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE ↗
  • Who funds Yale University ↗
  • Who funds CLINICAL DATA INTERCHANGE STANDARDS CONSORTIUM INC ↗
  • Who funds UNIVERSITY OF ROCHESTER ↗
  • Who funds INSTITUTE FOR ADVANCED CLINICAL TRIALS FOR CHILDREN ↗
  • Who funds MAYO CLINIC ↗
  • Who funds UNIVERSITY OF PITTSBURGH ↗
  • Who funds SEATTLE CHILDREN'S HOSPITAL ↗
  • Who funds WAKE FOREST UNIVERSITY HEALTH SCIENCES ↗
  • Who funds WASHINGTON UNIVERSITY ↗
  • Who funds JAEB CENTER FOR HEALTH RESEARCH FOUNDATION INC ↗
  • Who funds HMH HOSPITALS CORPORATION ↗
  • Who funds Banner Health ↗
  • Who funds Foundation for the National Institutes of Health Inc ↗

Co-funders

Grantmakers whose grantees overlap with this funder’s far more than size alone predicts. Closer means stronger alignment; arcs show where they also fund each other. Here they form a tightly interlocked group: most of these funders back each other's grantees too.

Vanderbilt University…Mayo ClinicYale UniversityThe Trustees of Colum…Johns Hopkins Univers…Cystic Fibrosis Found…The Children's Hospit…The Michael J Fox Fou…Cornell UniversityPublic Health Institu…American Cancer Socie…Charities Aid Foundat…
Vanderbilt University Medical CenterTN17.6× affinity6 shared granteesties to 11 of 11Hover any node to trace its alignments.Compare side by side →

Open a dossier: Vanderbilt University Medical Center · Mayo Clinic · Yale University · The Trustees of Columbia University in the City of New York · Johns Hopkins University · Cystic Fibrosis Foundation · The Children's Hospital of Philadelphia · The Michael J Fox Foundation for Parkinson's Research · Cornell University · Public Health Institute · American Cancer Society Inc · Charities Aid Foundation America

How this is measured
Affinity is a Gamma-Poisson posterior co-funding rate, re-centered on the typical rate, so thin evidence shrinks toward no signal. Overlap is association, not proof of shared intent.

How much its grantees rely on government

Each dot is one organization Critical Path Institute funds: left to right is the share of its income from government, bottom to top the share from Critical Path Institute. Bigger dots raise more.

2024
’20’21’22’23’24’25
no gov · 10%1%3%6%10%funder's share of their income ↑0%15%30%45%60%share of the org’s income from government →median 12%
  • Jaeb Center for Health Research Foundation Inc: 60% of income from government
  • Johns Hopkins University: 12% of income from government
  • Yale University: 12% of income from government
no gov moneyreceives it· size = income
1get no government money at all
2report government grants on their 990 we could not trace to a source (not plotted)
1rely on government for over half their income
⤢ axis zoomed · 0–60%
typical government reliance, FY20–25
How this is measured
Government income is each org’s traced federal awards (USASpending grants and contracts) plus state payments (open checkbooks) as a share of its total revenue (IRS Form 990); the self-reported government-grant line (990 line 1e) is carried for cross-check: a grantee that reports government grants we could not trace to a source is left off the chart rather than shown as receiving none. An association, not a claim that a grant caused the public funding. Coverage is precision-first, a floor rather than a census; state records exist for 9 states, so a grantee outside them shows no state figure (dimmed) rather than a false zero. Federal award amounts are obligations, which can span years, so a single-year share is indicative. 990 filings lag 12 to 24 months.
05Through Plinth

Warm introductions · Powered by PlinthPlus

How do I get to Critical Path Institute?

Find your warmest path to Critical Path Institute through trustees and officers whose names appear on both boards. Search for your organization and Plinth traces the shortest route it can evidence.

Each link is a name appearing on two organizations’ public IRS 990 filings, matched on that name and, where the filings support it, on location. A same-state match has geographic support, which is a second matching feature rather than confirmation that the two are one person; a cross-state one is the likeliest to be two people who share a name. Every hop shows its tier, low-confidence and distant paths are held back rather than guessed, and it is worth confirming the person before you use the introduction.

On method. Every financial figure here is read from IRS e-file XML, the funder’s own 990/990-PF, and from the multi-year returns of the 41 grantees we resolved, each linked to its source. Grantee outcomes are each organization’s own program-service reporting (Form 990, Part III), read as association with funding, never as caused by it. Low-confidence name matches are suppressed rather than guessed. How we build these →

How this is measured
Each figure carries one of six labels. Filed is what the funder reported on its return. Official is another government record about an organization, such as a federal award or a charity register, joined by name where no shared identifier exists. Resolved is an identity we worked out where the filing named a recipient without an EIN, kept only above a measured confidence threshold. Computed is arithmetic over those, like themes, portfolio clusters and co-funder strength. Context is a statistic about a place rather than about an organization, which is what the need overlay is: it describes the area a grantee’s address sits in, not where its work lands. Inferred is drawn by a model from text, like the partnerships read out of public news and organization websites. Each is labeled where it appears.

Generated from the IRS Form 990 e-file return for fiscal year 2025, released 2025. Filings run roughly 12 to 24 months behind; figures are dated accordingly.

Source object · view filing

Play a game based on Critical Path Institute’s filings →

More from the funding graph

The unnamed billions
grants reported with no recipient in the public record
The regranting layer
51% of grant dollars land in the regranting layer
The DAF merry-go-round
$9.7B circulates between donor-advised funds
The endowment market
who holds foundation money, and what just moved
The camps
funders cluster by geography, not ideology
By state
where grant money is based, and what stays home