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Arizona · Public charity

Critical Path Institute

The CRITICAL PATH INSTITUTE is a catalyst in the development of new approaches that advance medical innovation and regulatory science. This is achieved by leading teams that share data, knowledge and expertise resulting in sound, consensus based science.

$5.2M
Granted FY2025(still arriving)
17
Itemized grants FY2025
13
Organizations funded FY2024
23%
First-time grantees FY2024
Read the full brief
Itemized, FY2025
$3.8M
The rest is grants the schedule does not break out
Median grant, FY2025
$127,093
Largest grant, FY2025
$1,319,385
Organizations funded a year
6 to 13
FY2018 to FY2024
States reached, FY2025
12
Total assets, FY2025
$38M

How open it is to new grantees

In FY2024, 23% of the organizations Critical Path Institute funded were first-time grantees, receiving 5% of its grant dollars.

New vs renewed · share of each year

In FY2024, 95% of grant dollars renewed an existing relationship; $220k went to new ones.

50%100%’18’19’20’21’22’23’24
RenewedFirst-time

Where new relationships form · theme of each grantee’s first grant

’18’19’20’21’22’23’24
HealthEducationRecreation & SportsOther
How this is measured
First-time means a grantee’s first year in the filing window; renewed means funded in an earlier year too. The renewed share climbs naturally as a portfolio matures, so the signal is a year that bucks it (a wave of new grantees). The earliest year is left-censored: relationships that predate the data read as new. Theme is the grantee’s IRS cause.
The numbers by year
Fiscal yearOrganizations fundedTo those organizationsFirst-time grantees
FY2025still arriving16$3.6M63%
FY202413$4.6M23%
FY202311$4.0M0%
FY202211$3.8M36%
FY20219$2.9M78%
FY20209$2.5M44%
FY20199$1.9M33%
FY20186$1.2M33%
100% classified

What it funded, over time

Every grant placed by its stated purpose and the recipient’s mission, by year, FY2017 to 2025.

Health$20MEducation$4.8MRecreation & Sports$1.3MScience & Tech$635kReligion$50kCommunity Improvement$27kArts & Culture$24k

Where its grants go

Grant dollars by states, across the years we hold.

Which US states its grants reach

WA
MN
IL
MI
NY
MA
OH
PA
NJ
CT
CA
UT
CO
MO
MD
AZ
NC
GA
TX
FL

Top grantees

Largest recipients by total granted, FY2017 to FY2025, and the share of each one’s budget the grants supplied at peak.

GranteeTotal grantedYearsShare of their budget
National Organization for Rare Disorders Inc$9,187,66365%
Baylor Research Institute$3,778,87342%
Society of Critical Care Medicine$2,693,00134%
University of California San Francisco$1,972,2116n/a
Johns Hopkins University$1,277,14140%
Northwestern University$1,166,10670%
Emory University$1,000,00030%
The Translational Genomics Research Institute$723,53831%
Clinical Data Interchange Standards Consortium Inc$430,34633%
University of Arizona$374,4334n/a
Show all 39 grantees
All grantees of Critical Path Institute by total granted
GranteeTotal grantedYearsShare of their budget
National Organization for Rare Disorders Inc$9,187,66365%
Baylor Research Institute$3,778,87342%
Society of Critical Care Medicine$2,693,00134%
University of California San Francisco$1,972,2116n/a
Johns Hopkins University$1,277,14140%
Northwestern University$1,166,10670%
Emory University$1,000,00030%
The Translational Genomics Research Institute$723,53831%
Clinical Data Interchange Standards Consortium Inc$430,34633%
University of Arizona$374,4334n/a
Regents of the University of Michigan$367,3862n/a
University of Rochester$286,25830%
Institute for Advanced Clinical Trials for Children$250,33345%
Tufts Medical Center Parent Inc$238,2434n/a
University of Pittsburgh$237,50020%
Seattle Children's Hospital$234,72810%
Wake Forest University Health Sciences$215,7171n/a
Pennsylvania State University$187,5002n/a
Evidera Inc$184,8802n/a
Edetek Inc$167,5001n/a
Washington University$140,00010%
University of Florida$137,1004n/a
University Hospitals Health System Inc$127,0931n/a
Jaeb Center for Health Research Foundation Inc$126,73430%
Bioagilytix Labs$111,7671n/a
Hmh Hospitals Corporation$109,7981n/a
Banner Health$97,4881n/a
Rutgers the State University$81,7551n/a
Illumina Inc$77,3361n/a
University of Texas$60,0001n/a
Foundation for the National Institutes of Health Inc$57,07820%
Adelphi Values$50,3001n/a
Radyus Research$32,1001n/a
Myriad Rbm Inc$26,5101n/a
Xcures Inc$23,0001n/a
Verasci Inc Nct Holdings Inc$20,6801n/a
University of Utah$16,9201n/a
Cu Science Discovery$10,2001n/a
Colorado State University$8,5041n/a

Where it is load-bearing

Each grantee by its size and the share of its budget Critical Path Institute supplied at peak.

25%50%75%100%$10M$100Mgrantee revenue →↑ funder's share of their budgetNational Organization for Rare Disorders Inc: $9,187,663 over 6y, 4.8% of budgetBaylor Research Institute: $3,778,873 over 4y, 2.0% of budgetSociety of Critical Care Medicine: $2,693,001 over 3y, 4.2% of budgetJohns Hopkins University: $1,277,141 over 4y, 0.0% of budgetNorthwestern University: $1,166,106 over 7y, 0.0% of budgetEmory University: $1,000,000 over 3y, 0.0% of budgetThe Translational Genomics Research Institute: $723,538 over 3y, 0.5% of budgetClinical Data Interchange Standards Consortium Inc: $430,346 over 3y, 2.9% of budgetUniversity of Rochester: $286,258 over 3y, 0.0% of budgetInstitute for Advanced Clinical Trials for Children: $250,333 over 4y, 5.3% of budgetUniversity of Pittsburgh: $237,500 over 2y, 0.0% of budgetSeattle Children's Hospital: $234,728 over 1y, 0.0% of budgetWashington University: $140,000 over 1y, 0.0% of budgetJaeb Center for Health Research Foundation Inc: $126,734 over 3y, 0.3% of budgetFoundation for the National Institutes of Health Inc: $57,078 over 2y, 0.1% of budget

Tap a dot to name the grantee.

How this is measured
Share of budget is the funder’s grant in a year over the grantee’s total revenue that year, at its highest across the years we hold; revenue is from all sources. Only grantees confirmed against their own filings, whose grants do not exceed their revenue, are plotted: the largest 15.

Nonprofits that may fit its grantmaking

Co-funders

Grantmakers whose grantees overlap with this funder’s far more than size alone predicts. Closer means stronger alignment; arcs show where they also fund each other. Here they form a tightly interlocked group: most of these funders back each other's grantees too.

Vanderbilt University Medical CenterTN17.6× affinity6 shared granteesties to 11 of 11Hover any node to trace its alignments.Compare side by side →

Open a dossier: Vanderbilt University Medical Center · Mayo Clinic · Yale University · The Trustees of Columbia University in the City of New York · Johns Hopkins University · Cystic Fibrosis Foundation · The Children's Hospital of Philadelphia · The Michael J Fox Foundation for Parkinson's Research · Cornell University · Public Health Institute · American Cancer Society Inc · Charities Aid Foundation America

How this is measured
Affinity is a Gamma-Poisson posterior co-funding rate, re-centered on the typical rate, so thin evidence shrinks toward no signal. Overlap is association, not proof of shared intent.

Compare Critical Path Institute with peer funders

Warm introductions · Powered by PlinthPlus

How do I get to Critical Path Institute?

Find your warmest path to Critical Path Institute through trustees and officers whose names appear on both boards. Search for your organization and Plinth traces the shortest route it can evidence.

Each link is a name appearing on two organizations’ public IRS 990 filings, matched on that name and, where the filings support it, on location. A same-state match has geographic support, which is a second matching feature rather than confirmation that the two are one person; a cross-state one is the likeliest to be two people who share a name. Every hop shows its tier, low-confidence and distant paths are held back rather than guessed, and it is worth confirming the person before you use the introduction.

About Critical Path Institute

How much does Critical Path Institute give?
Critical Path Institute reported 17 itemized grants totaling $3,758,536, out of $5,186,032 in total grant expense reported on the return in its FY2025 IRS filing. It funded between 6 and 13 organizations a year over FY2018 to FY2024.
What does Critical Path Institute fund?
By grant dollars over FY2017 to FY2025, its largest causes are Health (74%), Education (18%), Recreation & Sports (5%).
Who are Critical Path Institute's largest grantees?
By total granted over FY2017 to FY2025: National Organization for Rare Disorders Inc ($9.2M), Baylor Research Institute ($3.8M), Society of Critical Care Medicine ($2.7M).
Does Critical Path Institute fund new organizations?
In FY2024, 23% of the organizations it funded were first-time grantees.
Which funders back the same organizations as Critical Path Institute?
Its strongest co-funders, measured against what their size predicts, include Vanderbilt University Medical Center, Mayo Clinic, Yale University.
Where is Critical Path Institute based?
Critical Path Institute is based in AZ.

On method. Every financial figure here is read from IRS e-file XML, the funder’s own 990/990-PF, and from the multi-year returns of the 41 grantees we resolved, each linked to its source. Grantee outcomes are each organization’s own program-service reporting (Form 990, Part III), read as association with funding, never as caused by it. Low-confidence name matches are suppressed rather than guessed. How we build these →

How this is measured
Each figure carries one of six labels. Filed is what the funder reported on its return. Official is another government record about an organization, such as a federal award or a charity register, joined by name where no shared identifier exists. Resolved is an identity we worked out where the filing named a recipient without an EIN, kept only above a measured confidence threshold. Computed is arithmetic over those, like themes, portfolio clusters and co-funder strength. Context is a statistic about a place rather than about an organization, which is what the need overlay is: it describes the area a grantee’s address sits in, not where its work lands. Inferred is drawn by a model from text, like the partnerships read out of public news and organization websites. Each is labeled where it appears.

Generated from the IRS Form 990 e-file return for fiscal year 2025, released 2025. Filings run roughly 12 to 24 months behind; figures are dated accordingly.

Source object · view filing

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