Skip to content
Alzheimer's Drug Discovery Foundation at a glanceMostly funded, not a grantmaker: see who funds it →

· Public charity

Alzheimer's Drug Discovery Foundation

Accelerate the discovery of drugs to prevent, treat and cure alzheimer's disease and related dementias.

$31M
Granted FY2025still arriving
23
Grants FY2025still arriving
15
States reached
$5.0M
Largest
01What it fundsRead
02The needRead
03Its granteesRead
04Its fieldRead
01What it funds
01100% classified

What it funded, over time

Every grant placed by its stated purpose and the recipient’s mission, by year, FY2017 to 2024.

Health$208MEducation$600kRecreation & Sports$500kSocial Science$250kScience & Tech$135k
02FY2025 · 23 grants

Where the money goes

Grants by size, and the largest recipients.

How this is measured
The 23 grants below total $16,077,916, the rows itemized in this filing. The $30,837,976 headline is the total grant expense on the return; the other $14,760,060 is giving the schedule does not break out (grants under the $5,000 itemization floor, grants to individuals, grants on other schedules). Every figure below describes the itemized rows only.

By grant size · FY2025

  • $10k–50k1 grant · $15k
  • $50k–250k4 grants · $517k
  • $250k+18 grants · $16M
$353,147
Median grant
15
States reached
$315M
Total assets
Largest grants
RecipientAmount
Individual grant recipient$4,995,519
ALZHEIMERS DISEASE DATA INITIATIVE (ADDI)$1,881,800
WASHINGTON UNIVERSITY IN ST LOUIS$1,687,500
SUPERFLUID DX$911,250
JOHNS HOPKINS UNIVERSITY$640,000
THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER AT DALLAS$600,000
UNIVERSITY OF ILLINOIS AT CHICAGO$599,515
ICAHN SCHOOL OF MEDICINE$598,982
INDIANA UNIVERSITY$502,277
EMTHERAPRO$499,415
CLEARVIEW HEALTHCARE PARTNERS$462,500
EMORY UNIVERSITY$353,147
STANFORD UNIVERSITY$350,385
UNIVERSITY OF PENNSYLVANIA$350,000
BETH ISRAEL DEACONESS MEDICAL CENTER$349,590
02The need
03

Does the money reach high-need areas?

Each grant placed by the hardship in its grantee’s ZIP, against the area’s typical level.

show:

Dollar for dollar, its grants (FY17–25) land where the poverty rate runs at 12%, against an area that typically sits at 10%. 66% of its dollars go to grantees based in above-average-need neighborhoods. Most of its grants land in higher-need ZIPs.

area typical 10%UNIVERSITY OF ARIZONA - HEALTH SCIENCES: $1.8M → 15%APRINOIA THERAPEUTICS INC: $4.4M → 8%METRO INTL BIOTECHEDENROC: $3.0M → 11%HARVARD MEDICAL SCHOOL: $2.0M → 16%DAVOS ALZHEIMERS COLLABORATIVE: $2.5M → 6%COGNITION THERAPEUTICS: $2.0M → 11%PREVENTIVE MED RESEARCH INST: $2.5M → 8%ALAMAR BIOSCIENCES: $10.0M → 10%THERINI BIO: $5.0M → 10%THE SCRIPPS RESEARCH INSTITUTE: $3.0M → 11%UNIVERSITY OF SOUTHERN CALIFO: $1.5M → 14%VACCINEX INC: $3.0M → 14%COYA THERAPEUTICS: $5.0M → 16%MTI BIOTECH INC: $1.4M → 17%MMS HOLDINGS: $1.6M → 21%WASHINGTON UNIVERSITY IN ST LOUIS: $1.7M → 11%C2N DIAGNOSTICS: $7.0M → 21%DUKE UNIVERSITY: $1.5M → 11%WAKE FOREST UNIVERSITY: $3.0M → 15%MINDIMMUNE THERAPEUTICS: $1.8M → 7%ALZHEIMERS DISEASE DATA INITIATIVE (ADDI): $1.9M → 9%CLEVELAND CLINIC LOU REVO CTR: $1.8M → 13%C2N DIAGNOSTICS LLC: $2.2M → 11%QUANTERIX CORPORATION: $2.3M → 8%DAVOS ALZHEIMERS COLLABORATIVE: $2.5M → 6%CURASEN THERAPEUTICS INC: $5.8M → 7%MEDARED: $3.0M → 10%ALZPATH INC: $1.9M → 11%VACCINEX: $1.8M → 14%LEXEO THERAPUTICS LLC: $2.0M → 17%GAP INNOVATIONS PBC: $1.5M → 14%UNIVERSITY OF RHODE ISLAND: $1.3M → 7%PHARMATROPHIX: $5.6M → 7%MODULO BIO INC: $4.8M → 11%NEROVISION IMAGING INC: $2.2M → 12%BIOLOGICAL DYNAMICS: $1.8M → 11%NEUROVISION IMAGING: $2.2M → 12%ACURASTEM INCORPORATED: $2.9M → 14%MOLECULAR STETHOSCOPE INC: $1.8M → 11%METRO INTERNATIONAL BIOTECH: $5.8M → 8%WEILL CORNELL MEDICAL COLLEGE: $3.0M → 17%METRO INTERNATIONAL BIOTECHEDENROC: $5.0M → 8%BOSTON UNIVERSITY: $2.1M → 16%TRANSPOSON THERAPEUTICS: $5.0M → 11%AQUINNAH PHARMACEUTICALS: $3.0M → 8%COGNITO THERAPEUTICS: $4.6M → 8%ELYSIUN HEALTH: $2.7M → 17%VIEWMIND: $1.4M → 17%0%20%40%50%more need →
grant to an above-average-need area below average· circle size = grant amount
How this is measured
Matched: human-services grants are those whose grantee’s IRS cause code is Human Services. Placed by people below the poverty line in the grantee’s ZIP, averaged from the tracts in that ZIP.

Which US states its grants reach

MN
IL
MI
NY
MA
NV
IA
IN
OH
PA
NJ
CT
RI
CA
UT
MO
KY
VA
MD
AZ
KS
TN
NC
DC
AL
GA
TX

Grants abroad, by region: $15M on the FY2025 return

Schedule F, as filed: 3 regions. The IRS asks for region and purpose, not the recipient, so no country or grantee can be named here.

Europe (including Iceland and Greenland)$13M · 90% · 14 grants

Stated purpose: RESEARCH

North America (Canada and Mexico)$1.0M · 7% · 1 grant

Stated purpose: RESEARCH

East Asia and the Pacific$493k · 3% · 2 grants

Stated purpose: RESEARCH

How this is measured
US grants placed by each grantee’s ZIP, which can differ from where services are delivered. Need from public data (U.S. Census/ACS, CDC PLACES, Eviction Lab, USDA), shown as context about the area, never attributed to the funder’s giving. Grants abroad on Schedule F are filed by region, purpose and amount with no recipient name, so they are shown by region and cannot be placed on the country map or matched to a grantee.
03Its grantees
repeat funding

Who it funds again

Organizations funded in more than one year, against those funded once.

43%of every dollar goes to organizations it has funded before.
$93M · 38 repeat orgs$125M to everyone else

Grantees it renews have grown median revenue +51% since the first grant, against +14% for those funded once.

38 repeat relationships: 9 still active in FY2025, 29 since wound down; 11 grantees were first funded in FY2025 (too recent to call).

How the two cohorts compare

Re-uppedFunded once

Organizations

38
93

Total granted

$93M
$114M

Median revenue growth · since first grant

+51%
+14%

Still filing today

32%
22%

New vs renewed · share of each year

In FY2025, 24% of grant dollars renewed an existing relationship; $12M went to new ones.

50%100%’17’18’19’20’21’22’23’24’25
RenewedFirst-time

Where new relationships form · theme of each grantee’s first grant

’17’18’19’20’21’22’23’24’25
HealthEducationOther
How this is measured
First-time means a grantee’s first year in the filing window; renewed means funded in an earlier year too. The renewed share climbs naturally as a portfolio matures, so the signal is a year that bucks it (a wave of new grantees). The earliest year is left-censored: relationships that predate the data read as new. Theme is the grantee’s IRS cause.

Backed again, and grew

  • DA
    DAVOS ALZHEIMER'S COLLABORATIVE INC
    2× · 2023–2024 · $5.0M · revenue +47% · 29% of their budget
  • THE CLEVELAND CLINIC FOUNDATION
    3× · 2018–2023 · $3.9M · revenue +55%
  • WAKE FOREST UNIVERSITY
    2× · 2020–2023 · $3.6M · revenue +45%

Funded once

  • AB
    ALAMAR BIOSCIENCES
    one grant, 2024 · $10M
  • CT
    CURASEN THERAPEUTICS INC
    one grant, 2023 · $5.8M
  • LE
    LIFESPAN EXTENSION ADVOCACY FOUNDATION
    one grant, 2023 · $5.8M · revenue -15%
How this is measured

Repeat means funded in two or more distinct years. Growth and survival are read from each grantee’s own subsequent IRS filings.

04Its field

Closest unfunded matches

The nonprofits that most resemble its grantees but are not funded by it, scored along the direction from the rest of the field toward the portfolio. A resemblance in what they say they do, not a recommendation.

1
New York University

Nyu is a private university with approximately 60,000 matriculating students in 20 schools and institutes. nyu's primary missions are education, research and scholarship, and patient care.

Education
2
University of Miami

See Form 990, Part I, Line 1, Description of Organization Mission.

Education
3
Sanford Burnham Prebys Medical Discovery Institute

Sanford burnham prebys medical discovery institute's mission is to advance the biomedical sciences by cultivating the next generation of scientific leaders, providing meaningful opportunities for researchers of all backgrounds to learn,…

Health
4
Albany College of Pharmacy and Health Sciences

We educate the next generation of leaders to improve the health of our society.

Education
5
Drexel University

Drexel university fulfills its founder's vision of preparing each new generation of students for productive professional and civic lives while also focusing its collective expertise on solving society's greatest problems. drexel is an…

Education
6
Fred Hutchinson Cancer Center

Fred hutch cancer center ("fred hutch") unites innovative research and compassionate care to prevent and eliminate cancer and infectious disease. continued on schedule o

Health
7
William Marsh Rice University

As a leading research university with a distinctive commitment to undergraduate education, Rice University aspires to path breaking research, unsurpassed teaching, and contributions to the betterment of our world. It seeks to fulfill this…

Education
8
Massachusetts Institute of Technology

The mission of mit is to advance knowledge and educate students in science, technology, and other areas of scholarship that will best serve the nation and the world in the 21st century.

Education
9
Rush University Medical Center

The mission of Rush is to improve the health of the individuals and diverse communities we serve through the integration of outstanding patient care, education, research and community partnerships.

Health
10
University of Minnesota Physicians

University of minnesota physicians serves as the integrated group practice for the university of minnesota medical school full-time faculty to provide the highest quality healthcare to patients and their families.university of minnesota…

Health
11
Massachusetts Eye & Ear Infirmary

THE MASSACHUSETTS EYE AND EAR INFIRMARY ("THE INFIRMARY") IS A NOT-FOR-PROFIT TEACHING HOSPITAL CONDUCTING PATIENT CARE AND RESEARCH. THE INFIRMARY IS A TEACHING HOSPITAL OF HARVARD MEDICAL SCHOOL AND AN INTERNATIONAL CENTER FOR RESEARCH.…

Health
12
New York Genome Center Inc

Operate a state-of-the-art, world-class genomic research center that creates and uses advanced genomics to understand the genetic basis of disease. for more information, see schedule o.

Health
How this is measured
The grantee most central to the portfolio’s shape is Trustees of Boston University; the most unlike its peers is Wake Forest University. Resemblance is measured on each organization’s own IRS 990 mission text; it reflects how work is described, not its quality or impact.
04the grantee network

44 grantees tracked through their own filings, 2017–2025.

Each grant beside the grantee’s revenue from every source, year by year.

How this is measured

Counted here: distinct organizations funded across 2017 to 2025, not grant rows in a single year, so this will not match the grant count on the cover. 44 of the 148 grantees resolved in that span have returns of their own we could reconcile.

Each grantee is resolved to its own IRS returns. Association, dated; never a causal claim.

3
Load-bearing (≥25% of a budget)
2
Early backer (in before they grew)
43/44
Grantees still filing
30/44
Grew since first funded

Where the money sits, by cause and then by grantee

ALAMAR BIOSCIENCES: $10,016,094 · OtherALAMAR BIOSCIENCESC2N Diagnostics: $9,250,358 · OtherMETRO INTERNATIONAL BIOTECHEDENROC: $8,000,000 · OtherTHERINI BIO: $8,000,000 · Other+104 more: $141,114,846 · Other+104 moreLIFESPAN EXTENSION ADVOCACY FOUNDATION: $5,750,000 · HealthLIFESPAN EXTENS…DAVOS ALZHEIMER'S COLLABORATIVE INC: $5,000,000 · HealthDAVOS ALZHEIMER…THE CLEVELAND CLINIC FOUNDATION: $3,869,258 · HealthTHE CLEVELAND C…THE SCRIPPS RESEARCH INSTITUTE: $3,000,000 · HealthTHE SCRIPPS RES…PREVENTIVE MEDICINE RESEARCH INSTITUTE: $2,500,000 · HealthPREVENTIVE MEDI…MAYO CLINIC: $2,134,439 · HealthMAYO CLINICAlzheimers Disease Data Initiative Inc: $1,881,800 · HealthAlzheimers Dise…Foundation for the National Institutes of Health Inc: $1,548,432 · HealthThe Bluefield Project to Cure Frontotemporal Dementia: $1,200,000 · HealthUSAGAINSTALZHEIMER'S: $1,115,000 · Health+11 more: $2,031,877 · Health+11 moreWAKE FOREST UNIVERSITY: $3,589,379 · EducationWAKE FORE…President and Fellows of Harvard College: $1,959,841 · EducationPresident…UNIVERSITY OF SOUTHERN CALIFORNIA: $1,750,483 · EducationUNIVERSIT…WASHINGTON UNIVERSITY: $1,687,500 · EducationWASHINGTO…DUKE UNIVERSITY: $1,631,197 · EducationDUKE UNIV…University of Kentucky Research Foundation: $1,434,160 · EducationUniversit…JOHNS HOPKINS UNIVERSITY: $1,387,825 · EducationJOHNS HOP…Emory University: $1,059,849 · EducationEmory Uni…THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY: $947,385 · EducationICAHN SCHOOL OF MEDICINE AT MOUNT SINAI: $704,982 · Education+9 more: $2,756,414 · Education+9 more
Other$176,381,298Health$30,030,806Education$18,909,015

Each grantee by its size and the funder’s share of it; top left is load-bearing

25%50%75%100%$10M$100Mgrantee revenue →↑ funder's share of their budgetDAVOS ALZHEIMER'S COLLABORATIVE INC: $5,000,000 over 2y, 29% of budgetTHE CLEVELAND CLINIC FOUNDATION: $3,869,258 over 3y, 0.0% of budgetWAKE FOREST UNIVERSITY: $3,589,379 over 2y, 0.5% of budgetTRUSTEES OF BOSTON UNIVERSITY: $3,232,829 over 5y, 0.1% of budgetTHE SCRIPPS RESEARCH INSTITUTE: $3,000,000 over 1y, 0.5% of budgetPREVENTIVE MEDICINE RESEARCH INSTITUTE: $2,500,000 over 1y, 95% of budgetMAYO CLINIC: $2,134,439 over 3y, 0.0% of budgetPresident and Fellows of Harvard College: $1,959,841 over 1y, 0.0% of budgetUNIVERSITY OF SOUTHERN CALIFORNIA: $1,750,483 over 2y, 0.0% of budgetWASHINGTON UNIVERSITY: $1,687,500 over 1y, 0.0% of budgetDUKE UNIVERSITY: $1,631,197 over 2y, 0.1% of budgetFoundation for the National Institutes of Health Inc: $1,548,432 over 5y, 0.8% of budgetUniversity of Kentucky Research Foundation: $1,434,160 over 1y, 0.4% of budgetJOHNS HOPKINS UNIVERSITY: $1,387,825 over 5y, 0.0% of budgetThe Bluefield Project to Cure Frontotemporal Dementia: $1,200,000 over 1y, 36% of budgetUSAGAINSTALZHEIMER'S: $1,115,000 over 4y, 10% of budgetEmory University: $1,059,849 over 4y, 0.0% of budgetTHE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY: $947,385 over 2y, 0.0% of budgetICAHN SCHOOL OF MEDICINE AT MOUNT SINAI: $704,982 over 2y, 0.0% of budgetCASE WESTERN RESERVE UNIVERSITY: $599,259 over 1y, 0.0% of budgetChildren's Hospital Corporation: $572,678 over 1y, 0.0% of budgetTHE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK: $388,506 over 2y, 0.0% of budgetTRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA: $350,000 over 1y, 0.0% of budgetBETH ISRAEL DEACONESS MEDICAL CENTER INC: $349,590 over 1y, 0.0% of budgetTHE ROCKEFELLER UNIVERSITY: $320,000 over 1y, 0.1% of budgetHebrew Rehabilitation Center: $319,609 over 1y, 0.2% of budgetUNIVERSITY OF CALIFORNIA BERKELEY FOUNDATION: $300,000 over 1y, 0.1% of budgetUSF RESEARCH FOUNDATION INC: $263,649 over 1y, 1.6% of budgetNORTHEASTERN UNIVERSITY: $250,000 over 1y, 0.0% of budgetDigital Medicine Society Inc: $210,000 over 1y, 3.1% of budgetVanderbilt University: $150,000 over 1y, 0.0% of budgetTHE J DAVID GLADSTONE INSTITUTES: $150,000 over 1y, 0.2% of budgetCornell University: $135,000 over 1y, 0.0% of budgetTHE MOUNT SINAI HOSPITAL: $100,000 over 1y, 0.0% of budgetTHE MILKEN INSTITUTE: $100,000 over 2y, 0.0% of budgetBIOTECHNOLOGY INNOVATION ORGANIZATION: $73,700 over 1y, 0.1% of budgetGlobal Alzheimer's Platform Foundation Inc: $50,000 over 2y, 0.4% of budgetTHE AMERICAN NEUROLOGICAL ASSOCIATION: $10,000 over 1y, 0.3% of budgetTHE ASSOCIATION FOR FRONTOTEMPORAL DEGENERATION: $10,000 over 1y, 0.0% of budgetLewy Body Dementia Association Inc: $10,000 over 1y, 0.4% of budget
Grantee by grantee: a decade per organization, before and after funding

A decade per grantee: revenue shaded, grants as bars, all rows on one timeline.

  • Who funds LIFESPAN EXTENSION ADVOCACY FOUNDATION ↗
  • Who funds DAVOS ALZHEIMER'S COLLABORATIVE INC ↗
  • Who funds THE CLEVELAND CLINIC FOUNDATION ↗
  • Who funds WAKE FOREST UNIVERSITY ↗
  • Who funds TRUSTEES OF BOSTON UNIVERSITY ↗
  • Who funds THE SCRIPPS RESEARCH INSTITUTE ↗
  • Who funds PREVENTIVE MEDICINE RESEARCH INSTITUTE ↗
  • Who funds MAYO CLINIC ↗
  • Who funds President and Fellows of Harvard College ↗

Co-funders

Grantmakers whose grantees overlap with this funder’s far more than size alone predicts. Closer means stronger alignment; arcs show where they also fund each other. Here they form a tightly interlocked group: most of these funders back each other's grantees too.

Alzheimer's Disease &…The Michael J Fox Fou…Amyotrophic Lateral S…Beth Israel Deaconess…Mayo ClinicPresident and Fellows…Yale UniversityThe Trustees of Colum…American Heart Associ…Marin Community Found…National Philanthropi…American Endowment Fo…
Alzheimer's Disease & Related Disorders Association IncIL32.2× affinity13 shared granteesties to 11 of 11Hover any node to trace its alignments.Compare side by side →

Open a dossier: Alzheimer's Disease & Related Disorders Association Inc · The Michael J Fox Foundation for Parkinson's Research · Amyotrophic Lateral Sclerosis Assn · Beth Israel Deaconess Medical Center Inc · Mayo Clinic · President and Fellows of Harvard College · Yale University · The Trustees of Columbia University in the City of New York · American Heart Association Inc · Marin Community Foundation · National Philanthropic Trust · American Endowment Foundation

How this is measured
Affinity is a Gamma-Poisson posterior co-funding rate, re-centered on the typical rate, so thin evidence shrinks toward no signal. Overlap is association, not proof of shared intent.

How much its grantees rely on government

Each dot is one organization Alzheimer's Drug Discovery Foundation funds: left to right is the share of its income from government, bottom to top the share from Alzheimer's Drug Discovery Foundation. Bigger dots raise more.

2024
’20’21’22’23’24’25
no gov · 10%6%25%56%100%funder's share of their income ↑0%23%45%68%90%share of the org’s income from government →median 12%
  • Hebrew Rehabilitation Center: 53% of income from government
  • Digital Medicine Society Inc: 14% of income from government
  • Trustees of Boston University: 12% of income from government
  • Johns Hopkins University: 12% of income from government
  • Children's Hospital Corporation: 10% of income from government
  • President and Fellows of Harvard College: 7% of income from government
  • Northeastern University: 7% of income from government
no gov moneyreceives it· size = income
1get no government money at all
1report government grants on their 990 we could not trace to a source (not plotted)
1rely on government for over half their income
⤢ axis zoomed · 0–90%
typical government reliance, FY20–25
How this is measured
Government income is each org’s traced federal awards (USASpending grants and contracts) plus state payments (open checkbooks) as a share of its total revenue (IRS Form 990); the self-reported government-grant line (990 line 1e) is carried for cross-check: a grantee that reports government grants we could not trace to a source is left off the chart rather than shown as receiving none. An association, not a claim that a grant caused the public funding. Coverage is precision-first, a floor rather than a census; state records exist for 9 states, so a grantee outside them shows no state figure (dimmed) rather than a false zero. Federal award amounts are obligations, which can span years, so a single-year share is indicative. 990 filings lag 12 to 24 months.

On method. Every financial figure here is read from IRS e-file XML, the funder’s own 990/990-PF, and from the multi-year returns of the 148 grantees we resolved, each linked to its source. Grantee outcomes are each organization’s own program-service reporting (Form 990, Part III), read as association with funding, never as caused by it. Low-confidence name matches are suppressed rather than guessed. How we build these →

How this is measured
Each figure carries one of six labels. Filed is what the funder reported on its return. Official is another government record about an organization, such as a federal award or a charity register, joined by name where no shared identifier exists. Resolved is an identity we worked out where the filing named a recipient without an EIN, kept only above a measured confidence threshold. Computed is arithmetic over those, like themes, portfolio clusters and co-funder strength. Context is a statistic about a place rather than about an organization, which is what the need overlay is: it describes the area a grantee’s address sits in, not where its work lands. Inferred is drawn by a model from text, like the partnerships read out of public news and organization websites. Each is labeled where it appears.

Generated from the IRS Form 990 e-file return for fiscal year 2025, released 2025. Filings run roughly 12 to 24 months behind; figures are dated accordingly.

Source object · view filing

Play a game based on Alzheimer's Drug Discovery’s filings →

More from the funding graph

The unnamed billions
grants reported with no recipient in the public record
The regranting layer
51% of grant dollars land in the regranting layer
The DAF merry-go-round
$9.7B circulates between donor-advised funds
The endowment market
who holds foundation money, and what just moved
The camps
funders cluster by geography, not ideology
By state
where grant money is based, and what stays home