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Indiana · Nonprofit

Regenstrief Institute Inc

Regenstrief Institute Inc (Indiana) receives grants from 7 organizations whose IRS filings report $8,333,998 to it, the largest being PATH ($5,068,154). 5 of them have funded it in more than one year.

Revenue FY2025
$26M
Funders on record
7
Grants received
$8.3M
Net assets
$35M
5/7 repeat funderspeak grant-dependency 7%
01What it does

What Regenstrief Institute Inc does

Mission

To improve health through research that enhances the quality and cost-effectiveness of health care, by functioning as a healthcare laboratory and community of scholars.

As stated on its FY2025 Form 990.

Programs

On its FY2024 return the organization reported a significant change in how it conducts a program.

The global health informatics division of the center for biomedical informatics was effectively eliminated due to changes in federal funding priorities.

Its own explanation, from Schedule O of that return (Part III, line 3).

  1. Regenstrief Data Services - Supports innovative healthcare research by providing access to Regenstrief Institute data assets and informatics expertise. Regenstrief Data Services assists investigators across all stages of research, from study design and data analysis to algorithm validation and implementation.

    $7,119,954 spent$1,926,574 earned by the program
    36% of program spending
  2. Center for Biomedical Informatics - Improving healthcare through informatics. Develop and apply health information technology solutions to generate knowledge about health, disease and treatment, help clinicians make optimal decisions, empower patients, and inform healthcare policy.

    $3,947,856 spentof which $57,244 as grants$577,850 earned by the program
    20% of program spending
  3. Health Data Standards (HDS) - Develops and maintains LOINC (Logical Observation Identifiers Names and Codes), a clinical terminology standard mandated for U.S. federal health programs and implemented internationally, and UCUM (Unified Code for Units of Measure) which supports consistent exchange of quantitative data in science, health care, and business. HDS also convenes global stakeholders to advance interoperable health data standards that enable effective data exchange, promote their adoption, and help shape the scientific and policy landscape related to research, public health, and patient care.

    $3,422,815 spent$149,410 earned by the program
    17% of program spending
  4. The William M. Tierney Center for Health Services Research - Conducts multidisciplinary research in clinical and community settings to improve the delivery and outcomes of health care services through innovative use of health information and health information technology.

    $2,841,379 spent$1,702,922 earned by the program
    15% of program spending
  5. Center for Aging Research - Develop, test, and implement innovative strategies to improve the quality and efficiency of healthcare and self-care for medically and socially vulnerable older adults. Explore new models of care for late life depression, dementia, delirium and other common geriatric syndromes. Subject descriptive clinical and demographic data; ability to study clinical outcomes and guidance in regard to data security.

    $2,231,675 spent$481,478 earned by the program
    11% of program spending
  6. IU Institute Support & IU Share Support

    $0 spent$800,000 earned by the program
    0% of program spending
  7. Miscellaneous Revenue

    $0 spent$208,812 earned by the program
    0% of program spending

The 7 programs described on its FY2024 Form 990, listed largest first by expense. Program spending in total: $19,563,679.

02The organization over time

The organization over time

Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20172017 Revenue 100 ($21M) Expenses 100 ($20M) Net assets 100 ($32M)2018 Revenue 89 ($19M) Expenses 101 ($21M) Net assets 95 ($31M)2019 Revenue 102 ($22M) Expenses 114 ($23M) Net assets 91 ($30M)2020 Revenue 98 ($21M) Expenses 115 ($23M) Net assets 84 ($27M)2021 Revenue 118 ($25M) Expenses 110 ($22M) Net assets 92 ($30M)2022 Revenue 161 ($35M) Expenses 116 ($24M) Net assets 120 ($39M)2023 Revenue 123 ($26M) Expenses 137 ($28M) Net assets 116 ($38M)2024 Revenue 115 ($25M) Expenses 137 ($28M) Net assets 110 ($36M)2025 Revenue 121 ($26M) Expenses 134 ($27M) Net assets 108 ($35M)
'17'18'19'20'21'22'23'24'25
Revenue (121)Expenses (134)Net assets (108)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2024 to 2025, from $48M to $38M (−20%).

$45M
$43M
$43M
$42M
$44M
$51M
$50M
$48M
$38M
'17'18'19'20'21'22'23'24'25
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2017
2018
2019
2020
2021
2022
2023
2024
2025
ContributionsProgram revenueInvestmentOther

Government-grant reliance: 2017 32% · 2018 36% · 2019 49% · 2020 40% · 2021 54% · 2022 52% · 2023 56% · 2024 64% · 2025 52%. Grants only. Government contracts and fees sit inside program revenue.

74% of Regenstrief Institute Inc’s revenue is contributions — more donation-reliant than the typical peer (23% for the typical peer).

This organization
Typical peer · 4,251 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 6 of the last 9 reported years ran a deficit.

$1.0M
’17
−$1.6M
’18
−$1.4M
’19
−$2.5M
’20
$2.9M
’21
$11M
’22
−$1.7M
’23
−$3.3M
’24
−$1.5M
’25
1.2
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Board chair

Craig Brater Md

Board Member, Chair

As listed on its FY2025 Form 990.

'17'18'19'20'21'22'23'24'25
Listed192220202022202020
Joined·+9+6+2+5+9+9+6+2
No longer listed·682571162
03Who funds it

Who funds it, year by year

2017 → 2023: the base broadened from 1 funder to 3 funders, grant income rose $5k → $1.4M.

Funder
'17
'18
'19
'20
'21
'22
'23
'24*
'25*
total
Pathunclassified
$5.1M
$395k
$111k
funders
1
3
3
3
3
4
3
3
1

1 of 7 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 1% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

Left out of every figure on this page: $51M from 4 payers (the payer shares this organization's board, largest Regenstrief Foundation Inc). These are real filings, and they are not money Regenstrief Institute Inc raised.

From the IRS filings of Regenstrief Institute Inc’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

Regenstrief Institute Inc leans on a few funders — its largest provides 61% of grant income and the top three 96%; half comes from just 1 funder.

the vertical line marks half of all grant income — 1 funder to its left

100% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund Regenstrief Institute Inc.

61%
largest funder
96%
top three
~2
effective funders

Largest funder’s share by year: 2017 100% · 2018 83% · 2019 82% · 2020 80% · 2021 70% · 2022 66% · 2023 94% — diversifying over time.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

Where its funders are

Regenstrief Institute Inc draws 70% of its grant income from funders outside Indiana, across 5 states in all.

WA
IL
IN
MD
TN

In-state vs out-of-state, by year

’17
’18
’19
’20
’21
’22
’23
Indiana out of state home

Funder states come from each funder’s own filing. $111k arriving through sponsors registered in 1 state is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

Regenstrief Institute Inc's funding base is broadening — from 1 funders to 3 as grant income climbed.

Operating margin−6% · bottom quartile
Months of reserve1.2mo · bottom quartile
Revenue growth (annualized)2% · bottom quartile

this organization peer median middle 50% of peers· 3,758 education nonprofits $10M–$100M, FY2025

Government funding Regenstrief Institute Inc receives

Grants and contracts to this organization from federal (USASpending) and state checkbooks, reconciled to its EIN. $42.8M on record.

Federal$42.8M
grants $5.6Mcontracts $37.2M
17
18
19
20
21
22
23
24
25
26
Top agencies
  • Department of Health and Human Services$42.8M

Federal grants vs contracts are distinguished; state line items keep their reported category. Matched by name + geography (the BMF), so coverage is partial and precision-first.

Organizations like Regenstrief Institute Inc

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In Indiana

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

72% of spending goes to programs.

Program 72%Management 28%Fundraising 0%

Governance

11
board members
27%
independent
✓Conflict-of-interest policy✓Whistleblower policy✓Document retention–Board reviewed the 990✓Audited financials

Footprint & structure

Files a return copy in 1 state

IN

Part of a family of 1 related entity

  • Indiana University · exempt

Screen this organization

A dated, signed PDF of the compliance screen for Regenstrief Institute Inc: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

A paid feature, included from the $75 plan up. Sign in to download.

Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds Regenstrief Institute Inc?
Regenstrief Institute Inc (Indiana) receives grants from 7 organizations whose IRS filings report $8,333,998 to it, the largest being PATH ($5,068,154). 5 of them have funded it in more than one year.
How many funders does Regenstrief Institute Inc have?
IRS filings report 7 organizations giving $8,333,998 in grants to Regenstrief Institute Inc, 5 of which have funded it in more than one year.
Who is the largest funder of Regenstrief Institute Inc?
PATH is the largest funder on record, with $5,068,154 in grants. The full list of funders is on this page.
How can an organization like Regenstrief Institute Inc find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in Indiana. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2017–2025), and the filings of 7 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing