Washington · Nonprofit
INSTITUTE FOR SYSTEMS BIOLOGY
INSTITUTE FOR SYSTEMS BIOLOGY (Washington) receives grants from 38 organizations whose IRS filings report $24,202,771 to it, the largest being GATES FOUNDATION ($4,157,745). 25 of them have funded it in more than one year.
- Revenue FY2024
- $42M
- Funders on record
- 38
- Grants received
- $24M
- Net assets
- $59M
What Institute for Systems Biology does
Mission
Non-profit research institute to advance a systems (or holistic and cross-disciplinary) approach to science; personalized medicine; global health & environmental sustainability; science education; & the pioneering & invention of biological & technological methods & tools.
As stated on its FY2024 Form 990.
Program
See schedule oat providence, we use our voice to advocate for vulnerable populations and needed reforms in health care. We are also pursuing innovative ways to transform health care by keeping people healthy, and making our services more convenient, accessible and affordable for all. In an increasingly uncertain world, we are committed to high-quality, compassionate care for everyone - regardless of coverage or ability to pay. We help people and communities benefit from the best health care model for the future - today.together, our 117,000 caregivers (all employees) serve in 51 hospitals, 1,000 clinics and a comprehensive range of health and social services across alaska, california, montana, new mexico, oregon, texas and washington. The providence family includes:-providence across seven western states-covenant health in west texas-providence facey medical foundation in los angeles, ca-kadlec in southeast washington-pacific medical centers in seattle, wa-swedish health services in seattle, waas a comprehensive health care organization, we are serving more people, advancing best practices and continuing our more than 100-year tradition of serving the poor and vulnerable.…
$33,689,837 spent$805,238 earned by the program100% of program spending
The program described on its FY2023 Form 990. Program spending in total: $33,689,837.
The organization over time
Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.
Balance sheet
Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2021 to 2022, from $82M to $127M (+55%).
How it's funded, over time
Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.
Government-grant reliance: 2017 49% · 2018 59% · 2019 63% · 2020 74% · 2021 67% · 2022 77% · 2023 57% · 2024 55%. Grants only. Government contracts and fees sit inside program revenue.
90% of INSTITUTE FOR SYSTEMS BIOLOGY’s revenue is contributions — more donation-reliant than the typical peer (52% for the typical peer).
Surplus & reserves
Operating surplus or deficit each year, and months of liquidity in hand. 7 of the last 8 reported years ran a deficit.
reserve
Leadership and staff
The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.
Board chair
Charles Watts Md
Board chair
As listed on its FY2024 Form 990.
Who funds it, year by year
2017 → 2023: the base broadened from 10 funders to 13 funders, grant income rose $2.4M → $2.5M.
8 of 38 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 12% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.
Left out of every figure on this page: $4.6M from 6 payers (the payer shares this organization's board, largest Seattle Children's Hospital). These are real filings, and they are not money INSTITUTE FOR SYSTEMS BIOLOGY raised.
From the IRS filings of INSTITUTE FOR SYSTEMS BIOLOGY’s funders (the co-funder graph). Top 30 of 38 funders by total. Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How concentrated its funding is
INSTITUTE FOR SYSTEMS BIOLOGY has a broad base — no single funder exceeds 17% of grant income, and it takes 4 funders to reach half.
the vertical line marks half of all grant income — 4 funders to its left
59% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund INSTITUTE FOR SYSTEMS BIOLOGY.
Largest funder’s share by year: 2017 43% · 2018 41% · 2019 18% · 2020 40% · 2021 35% · 2022 32% · 2023 21% — diversifying over time.
“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How long its funders stay
39% of INSTITUTE FOR SYSTEMS BIOLOGY's funders are still giving 3 years after their first grant; 66% give in more than one year at all.
Share of funders still giving k years after their first recorded grant, pooled across every acquisition cohort. A funder counts as retained in a year only if it made a grant that year. Measured to FY2023, the last fiscal year that has finished arriving — a funder cannot be counted as lapsed in a year most filers have not reached.
Where its funders are
INSTITUTE FOR SYSTEMS BIOLOGY draws 52% of its grant income from funders outside Washington, across 11 states in all.
In-state vs out-of-state, by year
Funder states come from each funder’s own filing. $2.9M arriving through sponsors registered in 6 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Against its field
INSTITUTE FOR SYSTEMS BIOLOGY has grown faster than half of the 149 science & tech nonprofits its size.
this organization peer median middle 50% of peers· 149 science & tech nonprofits $10M–$100M, FY2024
Government funding INSTITUTE FOR SYSTEMS BIOLOGY receives
Grants and contracts to this organization from federal (USASpending) and state checkbooks, reconciled to its EIN. $115.5M on record — $115.5M federal, $277 state.
- Department of Health and Human Services$100.4M
- National Science Foundation$11.3M
- Department of Defense$3.8M
- Department of Energy$50k
- REFUNDS - GENERAL $277
Federal grants vs contracts are distinguished; state line items keep their reported category. Matched by name + geography (the BMF), so coverage is partial and precision-first.
Organizations like INSTITUTE FOR SYSTEMS BIOLOGY
Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.
In Washington
Nationally
Read directly from this organization’s own Form 990, as neutral context.
Where the money goes
71% of spending goes to programs.
Governance
Public support
80%
Share of support from the public (Schedule A) — the basis for its public-charity status.
Footprint & structure
Files a return copy in 2 states
Part of a family of 181 related entities
- Collabria Care · exempt
- Covenant Aco · exempt
- Covenant Children's Physicians Group · exempt
- Covenant Health Partners · exempt
- Covenant Health System · exempt
Screen this organization
A dated, signed PDF of the compliance screen for INSTITUTE FOR SYSTEMS BIOLOGY: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.
Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf
Questions and answers
- Who funds INSTITUTE FOR SYSTEMS BIOLOGY?
- INSTITUTE FOR SYSTEMS BIOLOGY (Washington) receives grants from 38 organizations whose IRS filings report $24,202,771 to it, the largest being GATES FOUNDATION ($4,157,745). 25 of them have funded it in more than one year.
- How many funders does INSTITUTE FOR SYSTEMS BIOLOGY have?
- IRS filings report 38 organizations giving $24,202,771 in grants to INSTITUTE FOR SYSTEMS BIOLOGY, 25 of which have funded it in more than one year.
- Who is the largest funder of INSTITUTE FOR SYSTEMS BIOLOGY?
- GATES FOUNDATION is the largest funder on record, with $4,157,745 in grants. The full list of funders is on this page.
- How can an organization like INSTITUTE FOR SYSTEMS BIOLOGY find more funders?
- Start with the funders already giving here, then look at the foundations that back similar organizations in Washington. The funding by cause and by state pages list the largest funders for a given area and how to approach them.
Play a game about who funds Institute for Systems Biology →
These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2024 (financials across 2017–2024), and the filings of 38 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 22, 2026. What this page cannot tell you · view filing