Washington, D.C. · Nonprofit
HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE
HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE (Washington, D.C.) receives grants from 3 organizations whose IRS filings report $70,000 to it, the largest being FOUNDATION FOR CHEMISTRY RESEARCH AND INITIATIVES ($40,000). 1 of them have funded it in more than one year.
- Revenue FY2024
- $5.9M
- Funders on record
- 3
- Grants received
- $70k
- Net assets
- $6.9M
What Health and Environmental Sciences Institute does
Mission
The Health and Environmental Sciences Institute (hesi) is a nonprofit institution whose mission is to engage scientists from academia, government, industry, nonprofit, and other research institutions to identify and resolve global health and environmental issues.
As stated on its FY2024 Form 990.
Programs
Emerging systems toxicology for the assessment of risk (estar): the mission of this committee is to develop and deliver innovative systems toxicology approaches for risk assessment. This includes the catalyze adoption of new translational and predictive tools that guide decision-making based on mechanistic understanding of toxicological response, engaging the global scientific community to promote international acceptance of genomic biomarkers for decision-making, and identifying and characterizing biofluid and tissue-based genomic biomarkers for toxicology. The committee has six active projects, including the omics for assessing signatures for integrated safety (oasis) consortium, which is investigating the use of cell painting and transcriptomics from in vitro models and comparing them to existing rat in vivo data. Another project is evaluating the use of error corrected sequencing to detect clonal expansion induced by non-genotoxic carcinogens. Existing projects have made great progress as well in 2023. The tgx-ddi project was awarded a u01 grant from the us fda's biomarker qualification program, which allowed it to complete a multi-site trial for qualification. The committee…
$910,718 spentof which $652,838 as grants16% of program spendingCardiac safety technical committee: the mission of the cardiac safety technical committee is to improve public health by reducing unanticipated cardiovascular-related adverse effects from drugs or chemicals and develop innovative approaches to support early detection and prediction as well as improved understanding of cardiovascular toxicology and pathobiology. In 2023, the committee continued to sponsor projects addressing cardiovascular safety testing, published two scientific manuscripts in a peer-reviewed technical journal based on the committee's research and presented 9 times at public scientific meetings. An additional 6 manuscripts are in progress. Key projects included continuation of a new study to explore drug-induced blood pressure changes, a study to identify biomarkers of bleeding disorders, project planning to explore cardiac function and sodium channel block, and completion of data analysis for a new study to explore use of cardiac stem cells to predict toxicity. The committee also continued their support of two grants awarded through fda and nih in support of a strategic framework to enhance the use of mechanistic studies to predict potential cardiac risks for…
$901,354 spentof which $277,441 as grants$1,701 earned by the program16% of program spendingBotanical safety consortium (bsc): the bsc was officially convened in november 2019, as the result of a memorandum of understanding between the us fda, the national institutes of health's national institute of environmental health sciences (niehs), and the non-profit Health and Environmental Sciences Institute (hesi). The consortium is supported via us federal funding and private sector contributions to create a partnership to advance the science of botanical evaluation. With the engagement of a broad group of global stakeholders, the bsc's mission is to establish suitable levels of chemical characterization for botanicals and identify fit-for-purpose in vitro and in silico assays that can be used to evaluate botanical safety. The bsc is comprised of experts in areas related to pharmacognosy, natural products chemistry, modeling, toxicology, and/or new approach methodologies. An up-to-date list of participating organizations can be found at www.botanicalsafetyconsortium.org. Prioritized toxicity endpoints led to the formation of six endpoint working groups: hepatotoxicity, cardiotoxicity, neurotoxicity, genotoxicity, developmental and reproductive toxicity (dart), and systemic…
$380,158 spent7% of program spendingEco risk; in vitro genotoxicity; nitrosamine grant; dev and reproductive tox; ct tracs; protein allergenicity; immunotoxicology; annual meeting; thrive; communications and outreach; protac; uvcb; acsa 2; emerging issues cmte; cora ototoxicity; env epi ra; pb/pk; gratc; ra 21st century; neourotox biomarkers; fast fund; external advisory; prog strategy and stewardship; bioaccumulation; adc; hesi helps.
$3,425,869 spentof which $363,238 as grants$9,175 earned by the program61% of program spending
The 4 programs described on its FY2023 Form 990, listed largest first by expense. Program spending in total: $5,618,099.
The organization over time
Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.
Balance sheet
Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2021 to 2022, from $8.4M to $9.9M (+19%).
How it's funded, over time
Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.
Government-grant reliance: 2017 3% · 2018 1% · 2019 2% · 2020 20% · 2021 20% · 2022 21% · 2023 23% · 2024 11%. Grants only. Government contracts and fees sit inside program revenue.
96% of HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE’s revenue is contributions — more donation-reliant than the typical peer (67% for the typical peer).
Surplus & reserves
Operating surplus or deficit each year, and months of liquidity in hand. 3 of the last 8 reported years ran a deficit.
reserve
Leadership and staff
The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.
Chief executive
Dr Syril Pettit
Executive director
As listed on its FY2024 Form 990.
The chief executive listed changed between the FY2017 and FY2018 filings.
Who funds it, year by year
2019 → 2022: the base held at 1 funder, grant income fell $30k → $10k.
From the IRS filings of HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
How concentrated its funding is
HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE leans on a few funders — its largest provides 57% of grant income and the top three 100%; half comes from just 1 funder.
the vertical line marks half of all grant income — 1 funder to its left
100% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE.
Largest funder’s share by year: 2019 100% · 2021 100% · 2022 100% — broadly stable.
“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Where its funders are
100% of HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE's grant income comes from Washington, D.C. funders.
In-state vs out-of-state, by year
Funder states come from each funder’s own filing. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Against its field
HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE's revenue grew 67% between 2017 and 2024.
this organization peer median middle 50% of peers· 482 science & tech nonprofits $1M–$10M, FY2024
Government funding HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE receives
Grants and contracts to this organization from federal (USASpending) and state checkbooks, reconciled to its EIN. $4.3M on record.
- Department of Health and Human Services$4.3M
Federal grants vs contracts are distinguished; state line items keep their reported category. Matched by name + geography (the BMF), so coverage is partial and precision-first.
Organizations like HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE
Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.
In Washington, D.C.
Nationally
Read directly from this organization’s own Form 990, as neutral context.
Where the money goes
82% of spending goes to programs.
Governance
Public support
90%
Share of support from the public (Schedule A) — the basis for its public-charity status.
Footprint & structure
Files a return copy in 15 states
Screen this organization
A dated, signed PDF of the compliance screen for HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.
Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf
Questions and answers
- Who funds HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE?
- HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE (Washington, D.C.) receives grants from 3 organizations whose IRS filings report $70,000 to it, the largest being FOUNDATION FOR CHEMISTRY RESEARCH AND INITIATIVES ($40,000). 1 of them have funded it in more than one year.
- How many funders does HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE have?
- IRS filings report 3 organizations giving $70,000 in grants to HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE, 1 of which have funded it in more than one year.
- Who is the largest funder of HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE?
- FOUNDATION FOR CHEMISTRY RESEARCH AND INITIATIVES is the largest funder on record, with $40,000 in grants. The full list of funders is on this page.
- How can an organization like HEALTH AND ENVIRONMENTAL SCIENCES INSTITUTE find more funders?
- Start with the funders already giving here, then look at the foundations that back similar organizations in Washington, D.C.. The funding by cause and by state pages list the largest funders for a given area and how to approach them.
These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2024 (financials across 2017–2024), and the filings of 3 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing