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SynGAP Research Fund Incorporated at a glanceAlso receives grants: funding profile →

· Public charity

SynGAP Research Fund Incorporated

Improve the quality of life of SynGap-1 patients through the research and development of treatments, therapies and support systems.

$1.5M
Granted FY2024still arriving
8
Grants FY2024still arriving
8
States reached
$289k
Largest
01What it fundsRead
02The needRead
03Its granteesRead
04Its fieldRead
01What it funds
01100% classified

What it funded, over time

Every grant placed by its stated purpose and the recipient’s mission, by year, FY2020 to 2024.

Science & Tech$1.8MHealth$1.0MEducation$304kArts & Culture$191k
02FY2024 · 8 grants

Where the money goes

Grants by size, and the largest recipients.

How this is measured
The 8 grants below total $990,646, the rows itemized in this filing. The $1,492,904 headline is the total grant expense on the return; the other $502,258 is giving the schedule does not break out (grants under the $5,000 itemization floor, grants to individuals, grants on other schedules). Every figure below describes the itemized rows only.

By grant size · FY2024

  • $10k–50k1 grant · $30k
  • $50k–250k6 grants · $672k
  • $250k+1 grant · $289k
$96,197
Median grant
8
States reached
$2.8M
Total assets
Largest grants
RecipientAmount
Childrens Hospital Colorado$289,321
4M Therapeutics Inc$240,000
Univesity of California SF$130,000
Baylor College of Medicine$96,197
Unravel Biosciences Inc$90,500
University of Miami$65,000
New York University$50,000
Combined Brain$29,628
02The need
03

Does the money reach high-need areas?

Each grant placed by the hardship in its grantee’s ZIP, against the area’s typical level.

show:

Dollar for dollar, its grants (FY20–24) land where the poverty rate runs at 13%, against an area that typically sits at 12%. 56% of its dollars go to grantees based in above-average-need neighborhoods. Most of its grants land in higher-need ZIPs.

area typical 12%Unravel Biosciences Inc: $91k → 8%Axonis Therapeutics Inc: $55k → 16%University of Nebraska-Lincol: $100k → 13%University of Pennsylvania: $100k → 22%Rarebase PBC: $191k → 8%University of Southern Califo: $113k → 14%University of CA Davis: $80k → 16%New York University: $106k → 17%Baylor College of Medicine: $96k → 16%Scripps Research Institute: $69k → 11%University of Miami: $65k → 15%InVivo Biosystems: $10k → 15%Combined Brain: $30k → 4%University of Utah: $65k → 8%Childrens Hospital Colorado: $289k → 10%University of Colorado: $65k → 12%John Carroll University: $132k → 17%Johns Hopkins University: $250k → 19%The Jackson Laboratory: $237k → 11%Unravel Biosciences Inc: $45k → 8%University of Pennsylvania: $65k → 22%Stanford University: $130k → 8%University of Southern Califo: $65k → 14%University of CA Davis: $68k → 16%New York University: $50k → 17%Texas Childrens: $43k → 16%Scripps Research Institute: $69k → 11%Childrens Hospital Colorado: $113k → 10%John Carroll University: $7k → 17%Johns Hopkins University: $65k → 19%University of Southern Califo: $46k → 14%Baylor College of Medicine: $37k → 16%John Carroll University: $7k → 17%Johns Hopkins University: $40k → 19%0%20%40%50%more need →
grant to an above-average-need area below average· circle size = grant amount
How this is measured
Matched: human-services grants are those whose grantee’s IRS cause code is Human Services. Placed by people below the poverty line in the grantee’s ZIP, averaged from the tracts in that ZIP.

Which US states its grants reach

ME
NY
MA
OR
OH
PA
NJ
CA
UT
CO
NE
MD
TN
TX
FL

Grants abroad, by region: $419k on the FY2024 return

Schedule F, as filed: 1 region. The IRS asks for region and purpose, not the recipient, so no country or grantee can be named here.

Europe (including Iceland and Greenland)$419k · 100% · 2 grants

Stated purpose: Scientific Research

How this is measured
US grants placed by each grantee’s ZIP, which can differ from where services are delivered. Need from public data (U.S. Census/ACS, CDC PLACES, Eviction Lab, USDA), shown as context about the area, never attributed to the funder’s giving. Grants abroad on Schedule F are filed by region, purpose and amount with no recipient name, so they are shown by region and cannot be placed on the country map or matched to a grantee.
03Its grantees
repeat funding

Who it funds again

Organizations funded in more than one year, against those funded once.

43%of every dollar goes to organizations it has funded before.
$1.2M · 7 repeat orgs$1.6M to everyone else

Grantees it renews have grown median revenue +17% since the first grant, against +14% for those funded once.

7 repeat relationships: 3 still active in FY2024, 4 since wound down; 5 grantees were first funded in FY2024 (too recent to call).

How the two cohorts compare

Re-uppedFunded once

Organizations

7
9

Total granted

$1.2M
$879k

Median revenue growth · since first grant

+17%
+14%

Still filing today

71%
33%

New vs renewed · share of each year

In FY2024, 24% of grant dollars renewed an existing relationship; $754k went to new ones.

50%100%’20’21’22’23’24
RenewedFirst-time

Where new relationships form · theme of each grantee’s first grant

’20’21’22’23’24
HealthEducationOther
How this is measured
First-time means a grantee’s first year in the filing window; renewed means funded in an earlier year too. The renewed share climbs naturally as a portfolio matures, so the signal is a year that bucks it (a wave of new grantees). The earliest year is left-censored: relationships that predate the data read as new. Theme is the grantee’s IRS cause.

Backed again, and grew

  • JOHNS HOPKINS UNIVERSITY
    3× · 2021–2023 · $355k · revenue +40%
  • NY
    New York University
    2× · 2023–2024 · $156k · revenue +11%
  • John Carroll University
    3× · 2021–2023 · $147k · revenue +11%

Funded once

  • TJ
    THE JACKSON LABORATORY
    one grant, 2023 · $237k · revenue +14%
  • RP
    Rarebase PBC
    one grant, 2023 · $191k
  • CH
    Children's Hospital Colorado
    one grant, 2023 · $113k · revenue +7%
How this is measured

Repeat means funded in two or more distinct years. Growth and survival are read from each grantee’s own subsequent IRS filings.

04Its field

Closest unfunded matches

The nonprofits that most resemble its grantees but are not funded by it, scored along the direction from the rest of the field toward the portfolio. A resemblance in what they say they do, not a recommendation.

1
The Johns Hopkins Hospital

For more than 125 years, the mission of the johns hopkins hospital has been to lead the world in the diagnosis and treatment of disease and to train tomorrow's great physicians, nurses and scientists. above all, we aim to provide the…

Health
2
Drexel University

Drexel university fulfills its founder's vision of preparing each new generation of students for productive professional and civic lives while also focusing its collective expertise on solving society's greatest problems. drexel is an…

Education
3
Southern California University of Health Sciences

The mission of southern california university of health sciences (scu) is to educate students as competent, caring and successful practitioners of integrative healthcare. the university is committed to providing excellence in academics,…

Education
4
University of Minnesota Physicians

University of minnesota physicians serves as the integrated group practice for the university of minnesota medical school full-time faculty to provide the highest quality healthcare to patients and their families.university of minnesota…

Health
5
William Marsh Rice University

As a leading research university with a distinctive commitment to undergraduate education, Rice University aspires to path breaking research, unsurpassed teaching, and contributions to the betterment of our world. It seeks to fulfill this…

Education
6
Albany College of Pharmacy and Health Sciences

We educate the next generation of leaders to improve the health of our society.

Education
7
Thomas Jefferson University

Thomas jefferson university ("tju") is a comprehensive university with preeminence in transdisciplinary, experiential professional education, research and discovery, delivering exceptional value for the 21st century students with…

Education
8
Cedars-Sinai Medical Center

As a leading academic healthcare organization, our mission is to elevate the health status of the communities we serve.(see schedule o for continuation)(continued)-we deliver exceptional healthcare enhanced by research and education-we…

Health
9
Fred Hutchinson Cancer Center

Fred hutch cancer center ("fred hutch") unites innovative research and compassionate care to prevent and eliminate cancer and infectious disease. continued on schedule o

Health
10
Washington University

The washington university is a co-educational, nondenominational university with a long and distinguished history of teaching, research and (cont'd on schedule o)

Education
11
Memorial Sloan-Kettering Cancer Center

Leadership in the prevention, treatment, and cure of cancer through excellence, vision and cost effectiveness in patient care, outreach programs, research, and education.

Health
12
Hugo W Moser Research Institute At Kennedy Krieger Inc

The hugo w. moser research institute at kennedy krieger, inc. (the "research institute") is an internationally recognized research facility finding answers to problems and injuries that affect a child's developing brain. researchers have…

Science & Tech
How this is measured
The grantee most central to the portfolio’s shape is The Board of Trustees of the Leland Stanford Junior University; the most unlike its peers is Combinedbrain Inc. Resemblance is measured on each organization’s own IRS 990 mission text; it reflects how work is described, not its quality or impact.
04the grantee network

14 grantees tracked through their own filings, 2017–2025.

Each grant beside the grantee’s revenue from every source, year by year.

How this is measured

Counted here: distinct organizations funded across 2017 to 2025, not grant rows in a single year, so this will not match the grant count on the cover. 14 of the 24 grantees resolved in that span have returns of their own we could reconcile.

Each grantee is resolved to its own IRS returns. Association, dated; never a causal claim.

0
Load-bearing (≥25% of a budget)
0
Early backer (in before they grew)
14/14
Grantees still filing
11/14
Grew since first funded

Where the money sits, by cause and then by grantee

JOHNS HOPKINS UNIVERSITY: $355,000 · EducationJOHNS HOPKINS UNIVERSITYUNIVERSITY OF SOUTHERN CALIFORNIA: $224,164 · EducationUNIVERSITY OF SOUTHERN CALIFORNIATRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA: $165,000 · EducationTRUSTEES OF THE UNIVERSITY OF PENNSYLVANIANew York University: $155,819 · EducationNew York UniversityJohn Carroll University: $146,634 · EducationJohn Carroll UniversityBaylor College of Medicine: $132,772 · EducationBaylor College of MedicineTHE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY: $130,000 · EducationTHE BOARD OF TRUSTEES OF THE LELAND STANFORD J…University of Miami: $65,000 · Education4M Therapeutics Inc: $240,000 · Other4M Therapeutics IncRarebase PBC: $190,950 · OtherRarebase PBCUNIVERSITY OF CALIFORNIA DAVIS: $148,000 · OtherUNIVERSITY OF CALIFORNIA DAVISUnravel Biosciences Inc: $135,750 · OtherUnravel Biosciences IncUNIVERSITY OF CALIFORNIA SAN FRANCISCO: $130,000 · OtherUNIVERSITY OF CALIFORNIA SAN FRANCISCOBOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA: $99,909 · OtherBOARD OF REGENTS OF THE UNIVERSITY OF …UNIVERSITY OF UTAH: $65,377 · OtherUNIVERSITY OF UTAHREGENTS OF THE UNIVERSITY OF COLORADO: $65,000 · OtherREGENTS OF THE UNIVERSITY OF COLORADOAxonis Therapeutics Inc: $55,000 · Other+1 more: $10,000 · OtherChildren's Hospital Colorado Foundation: $289,321 · HealthChildren's Hospital Colorado…THE JACKSON LABORATORY: $236,850 · HealthTHE JACKSON LABORATORYTHE SCRIPPS RESEARCH INSTITUTE: $137,000 · HealthTHE SCRIPPS RESEARCH INSTITU…Children's Hospital Colorado: $113,000 · HealthChildren's Hospital ColoradoTexas Children's Hospital: $43,333 · HealthCOMBINEDBRAIN INC: $29,628 · Health
Education$1,374,389Other$1,139,986Health$849,132

Each grantee by its size and the funder’s share of it; top left is load-bearing

25%50%75%100%$10M$100Mgrantee revenue →↑ funder's share of their budgetJOHNS HOPKINS UNIVERSITY: $355,000 over 3y, 0.0% of budgetChildren's Hospital Colorado Foundation: $289,321 over 1y, 0.4% of budgetTHE JACKSON LABORATORY: $236,850 over 1y, 0.0% of budgetUNIVERSITY OF SOUTHERN CALIFORNIA: $224,164 over 3y, 0.0% of budgetTRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA: $165,000 over 2y, 0.0% of budgetNew York University: $155,819 over 2y, 0.0% of budgetJohn Carroll University: $146,634 over 3y, 0.1% of budgetTHE SCRIPPS RESEARCH INSTITUTE: $137,000 over 2y, 0.0% of budgetBaylor College of Medicine: $132,772 over 2y, 0.0% of budgetTHE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY: $130,000 over 1y, 0.0% of budgetChildren's Hospital Colorado: $113,000 over 1y, 0.0% of budgetUniversity of Miami: $65,000 over 1y, 0.0% of budgetTexas Children's Hospital: $43,333 over 1y, 0.0% of budgetCOMBINEDBRAIN INC: $29,628 over 1y, 2.5% of budget
Grantee by grantee: a decade per organization, before and after funding

A decade per grantee: revenue shaded, grants as bars, all rows on one timeline.

How much its grantees rely on government

Each dot is one organization SynGAP Research Fund Incorporated funds: left to right is the share of its income from government, bottom to top the share from SynGAP Research Fund Incorporated. Bigger dots raise more.

2024
’20’21’22’23’24’25
no gov · 00%0%1%3%5%funder's share of their income ↑0%15%30%45%60%share of the org’s income from government →median 12%
  • Johns Hopkins University: 12% of income from government
  • University of Miami: 5% of income from government
no gov moneyreceives it· size = income
0get no government money at all
2report government grants on their 990 we could not trace to a source (not plotted)
0rely on government for over half their income
⤢ axis zoomed · 0–60%
typical government reliance, FY20–25
How this is measured
Government income is each org’s traced federal awards (USASpending grants and contracts) plus state payments (open checkbooks) as a share of its total revenue (IRS Form 990); the self-reported government-grant line (990 line 1e) is carried for cross-check: a grantee that reports government grants we could not trace to a source is left off the chart rather than shown as receiving none. An association, not a claim that a grant caused the public funding. Coverage is precision-first, a floor rather than a census; state records exist for 9 states, so a grantee outside them shows no state figure (dimmed) rather than a false zero. Federal award amounts are obligations, which can span years, so a single-year share is indicative. 990 filings lag 12 to 24 months.

On method. Every financial figure here is read from IRS e-file XML, the funder’s own 990/990-PF, and from the multi-year returns of the 24 grantees we resolved, each linked to its source. Grantee outcomes are each organization’s own program-service reporting (Form 990, Part III), read as association with funding, never as caused by it. Low-confidence name matches are suppressed rather than guessed. How we build these →

How this is measured
Each figure carries one of six labels. Filed is what the funder reported on its return. Official is another government record about an organization, such as a federal award or a charity register, joined by name where no shared identifier exists. Resolved is an identity we worked out where the filing named a recipient without an EIN, kept only above a measured confidence threshold. Computed is arithmetic over those, like themes, portfolio clusters and co-funder strength. Context is a statistic about a place rather than about an organization, which is what the need overlay is: it describes the area a grantee’s address sits in, not where its work lands. Inferred is drawn by a model from text, like the partnerships read out of public news and organization websites. Each is labeled where it appears.

Generated from the IRS Form 990 e-file return for fiscal year 2024, released 2024. Filings run roughly 12 to 24 months behind; figures are dated accordingly.

Source object · view filing

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More from the funding graph

The unnamed billions
grants reported with no recipient in the public record
The regranting layer
51% of grant dollars land in the regranting layer
The DAF merry-go-round
$9.7B circulates between donor-advised funds
The endowment market
who holds foundation money, and what just moved
The camps
funders cluster by geography, not ideology
By state
where grant money is based, and what stays home