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Tennessee · Nonprofit

COMBINEDBRAIN INC

COMBINEDBRAIN INC (Tennessee) receives grants from 10 organizations whose IRS filings report $880,744 to it, the largest being Silicon Valley Community Foundation ($600,000). 3 of them have funded it in more than one year, and 72% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.

Revenue FY2024
$1.2M
Funders on record
10
Grants received
$881k
Net assets
$419k
3/10 repeat funderspeak grant-dependency 45%
01What it does

What Combinedbrain Inc does

Mission

The consortium for outcome measures and biomarkers for neurodevelopmental disorders is a non-profit organization devoted to speeding the path to clinical treatments for people with rare genetic neurodevelopmental disorders by pooling efforts, studies, and data.

As stated on its FY2024 Form 990.

Programs

  1. Biorepository: in a 2024 strategic planning process, surveys were sent separately to the clinical advisory board (cab), scientific advisory board (sab), patient advocacy advisory board (pab) and industry advisory board (iab), and each independently prioritized biomarker studies above all other efforts. Across all of the advisory boards, natural history was the second most commonly chosen area of concern, but amongst the pab, construction of research strategic plans was the second highest priority. Based on these priorities, combinedbrain has focused extensive efforts on hosting a biorepository and organizing pre-competitive biomarker projects. The repository is funded and governed by member pags.

    $725,850 spentof which $8,000 as grants$428,224 earned by the program
    67% of program spending
  2. Rent a neuroscientist: to respond to the pab request for help with strategic research plans, combinedbrain hires post-doctoral fellows, and student interns. These teams staff the rent-a-brain program, which assists with the roadshow, but primarily serves as part-time scientific officers for member pags. When requested, these teams review the landscape of drug development for a given disorder in an objective and economical way, resulting in a series of recommendations for moving as fast as possible from diagnosis to an fda-approved drug. The rent-a-brain teams also assist pags with grant applications, grant reviews, literature summaries, disease concept studies, and manuscript preparation. Renta-brain activities vary widely, as demanded by the pags and advisory boards. For example, one team has prepared scientific rationale for adding member disorders to diagnostic microarrays, another has prepared applications for icd-10 codes, and another has drafted a survey of toileting abilities to be piloted across neurodevelopmental disorders, amongst many other projects.

    $362,141 spentof which $8,000 as grants$82,782 earned by the program
    33% of program spending

The 2 programs described on its FY2024 Form 990, listed largest first by expense. Program spending in total: $1,087,991.

02The organization over time

The organization over time

Each line starts at 100 in 2021, so what you read is the shape rather than the size: 150 means half as much again as 2021, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20212021 Revenue 100 ($131k) Expenses 100 ($131k) Net assets 100 ($41k)2022 Revenue 560 ($736k) Expenses 403 ($528k) Net assets 638 ($259k)2023 Revenue 869 ($1.1M) Expenses 672 ($880k) Net assets 1285 ($522k)2024 Revenue 909 ($1.2M) Expenses 991 ($1.3M) Net assets 1031 ($419k)
2021202220232024
Revenue (909)Expenses (991)Net assets (1031)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2021 to 2022, from $41k to $358k (+781%).

$41k
$358k
$591k
$632k
2021202220232024
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2021
2022
2023
2024
ContributionsProgram revenueInvestmentOther

Government-grant reliance: 2022 13% · 2023 9% · 2024 9%. Grants only. Government contracts and fees sit inside program revenue.

57% of COMBINEDBRAIN INC’s revenue is contributions — more donation-reliant than the typical peer (51% for the typical peer).

This organization
Typical peer · 8,611 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 1 of the last 4 reported years ran a deficit.

$492
’21
$208k
’22
$263k
’23
−$103k
’24
4.0
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Chief executive

Terry Jo Bichell

Executive director

Board chair

Amber Freed

Chair

As listed on its FY2024 Form 990.

202220232024
Listed141415
Joined·+2+4
No longer listed·23
03Who funds it

Who funds it, year by year

2022 → 2023: the base broadened from 3 funders to 5 funders, grant income rose $276k → $513k.

2 of 10 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 72% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

From the IRS filings of COMBINEDBRAIN INC’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

COMBINEDBRAIN INC leans on a few funders — its largest provides 68% of grant income and the top three 81%; half comes from just 1 funder.

the vertical line marks half of all grant income — 1 funder to its left

100% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund COMBINEDBRAIN INC.

68%
largest funder
81%
top three
~2
effective funders

Largest funder’s share by year: 2022 72% · 2023 78% — growing more concentrated.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

Where its funders are

72% of COMBINEDBRAIN INC's grant income arrives through donor-advised or pass-through sponsors, whose addresses record where the money is held rather than where the donor is. Of the $243k that is directly attributable, 100% of it comes from funders outside Tennessee, across 8 states.

ME
WA
PA
NJ
CT
CA
DC
TX

In-state vs out-of-state, by year

’22
’23
Tennessee out of state home

Funder states come from each funder’s own filing. $637k arriving through sponsors registered in 2 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

COMBINEDBRAIN INC has grown faster than three-quarters of the 8,121 health nonprofits its size.

Operating margin−9% · bottom quartile
Months of reserve4.0mo · above the median
Revenue growth (annualized)109% · top quartile

this organization peer median middle 50% of peers· 8,121 health nonprofits $1M–$10M, FY2024

Organizations like COMBINEDBRAIN INC

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In Tennessee

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

84% of spending goes to programs.

Program 84%Management 16%Fundraising 0%

Governance

13
board members
100%
independent
–Conflict-of-interest policy–Whistleblower policy–Document retention✓Board reviewed the 990✓Audited financials

Public support

88%

Share of support from the public (Schedule A) — the basis for its public-charity status.

Footprint & structure

Files a return copy in 1 state

TN

Screen this organization

A dated, signed PDF of the compliance screen for COMBINEDBRAIN INC: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds COMBINEDBRAIN INC?
COMBINEDBRAIN INC (Tennessee) receives grants from 10 organizations whose IRS filings report $880,744 to it, the largest being Silicon Valley Community Foundation ($600,000). 3 of them have funded it in more than one year, and 72% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
How many funders does COMBINEDBRAIN INC have?
IRS filings report 10 organizations giving $880,744 in grants to COMBINEDBRAIN INC, 3 of which have funded it in more than one year.
Who is the largest funder of COMBINEDBRAIN INC?
Silicon Valley Community Foundation is the largest funder on record, with $600,000 in grants. The full list of funders is on this page.
How can an organization like COMBINEDBRAIN INC find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in Tennessee. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2024 (financials across 2021–2024), and the filings of 10 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing