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· Public charity

International Rett Syndrome Foundation

To accelerate full spectrum research to cure Rett syndrome and empower families with knowledge and connectivity.

$1.9M
Granted FY2024still arriving
12
Grants FY2024still arriving
9
States reached
$300k
Largest
01What you fund
01100% classified

What you funded, over time

Every grant placed by its stated purpose and the recipient’s mission, by year — across FY20172024.

Health$9.9M
02FY2024 · 12 grants

Where the money goes

Your grants by size, and where they go.

The 12 grants below total $1,678,482 — the rows itemised in this filing. The $1,856,999 headline is the total grant expense reported on the return, so the remaining $178,517 is giving the schedule does not break out: grants under the $5,000 itemisation floor, grants to individuals, and grants reported on other schedules. Every figure below describes the itemised rows only.

By grant size · FY2024

  • $50k–250k10 grants · $1.1M
  • $250k+2 grants · $600k
$125,000
Median grant
9
States reached
$5.3M
Total assets
Largest grants
RecipientAmount
The General Hospital Corporation dba Massachusetts General Hospital$300,000
University of Wisconsin-Madison$300,000
Vanderbilt University$137,500
The University of Texas Southwestern Medical Center$137,500
The Regents of the University of Colorado$137,500
University of Colorado Denver$125,000
North Carolina State University$120,982
The Rockefeller University$120,000
University of Virginia Rector & Visitors$100,000
The University of North Carolina at Chapel Hill$100,000
Whitehead University$50,000
Regents of the University of California$50,000
02The need
03

Do your dollars go where the need is?

Each grant placed by the hardship in its grantee’s ZIP, then read against the area’s typical level.

show:

Dollar for dollar, your grants (FY17–24) land where the poverty rate runs at 13%, against an area that typically sits at 11%. 63% of your dollars go to grantees based in above-average-need neighborhoods. Most of your grants land in higher-need ZIPs.

area typical 11%Children's Hospital Boston: $150k → 16%The Regents of the University of California US San Diego: $150k → 10%Sanford Burnham Prebys Medical Center: $75k → 11%The Regents of University of California: $150k → 14%Psychogenics Inc: $450k → 9%Syracuse University: $150k → 14%The Rockefeller University: $120k → 17%Albert Einstein College of Medicine: $150k → 28%University of Texas Southwestern: $138k → 14%Baylor College of Medicine: $250k → 16%Greenwood Genetic Center: $125k → 18%Georgetown University: $75k → 14%University of Wisconsin: $300k → 10%Vanderbilt University: $425k → 14%North Carolina State University: $121k → 8%Duke University: $150k → 11%The University of North Carolina at Chapel Hill: $100k → 13%North Carolina State University: $150k → 20%University of Colorado: $150k → 12%The Regents of the University of Colorado: $138k → 12%Loyola University Chicago: $150k → 14%University of Virginia Rector & Visitors: $100k → 8%Boston Children's Hospital: $150k → 16%University of Pennsylvania: $75k → 22%The Regents of the University of California US San Diego: $100k → 10%Psychogenics Inc: $300k → 9%The Rockefeller University: $120k → 17%The University of Texas Southwestern Medical Center: $138k → 14%Baylor College of Medicine: $100k → 16%Greenwood Genetic Center: $125k → 18%University of Wisconsin-Madison: $300k → 10%Vanderbilt University: $175k → 14%University of North Carolina at Chapel Hill: $100k → 13%North Carolina State University: $121k → 20%The Regents of University of Colorado: $138k → 12%Loyola Univeristy Chicago: $150k → 14%Boston Children's Hospital: $75k → 16%The Regents of the University of California US San Diego: $75k → 10%University of Texas Southwestern Medical Center: $89k → 14%University of Wisconsin at Madison: $150k → 10%Vanderbilt University: $138k → 14%The General Hospital Corporation dba Massachusetts General Hospital: $300k → 8%Massachusetts General Hospital: $150k → 16%University of California San Diego: $142k → 11%Massachusetts General Hospital: $600k → 16%University of California San Diego: $150k → 11%University of California San Diego: $150k → 11%University of California UC San Diego: $75k → 11%0%20%40%50%more need →
grant to an above-average-need area below average· circle size = grant amount

Matched: human-services grants are those whose grantee’s IRS cause code is Human Services. Placed by people below the poverty linein the grantee’s ZIP, averaged from the tracts in that ZIP; grantee ZIP can differ from where services are delivered.

Which US states your grants reach

IL
WI
NY
MA
OH
PA
NJ
CA
CO
VA
TN
NC
SC
DC
AL
TX
FL

US grants placed by each grantee’s ZIP, which can differ from where services are actually delivered. Need from public data — U.S. Census/ACS, CDC PLACES, Eviction Lab, USDA — shown as context about the area, never attributed to your giving.

03Your edge
repeat funding

Who you back again

Which organizations you funded more than once, and which you funded a single time. Each grantee is matched to its own filings.

78%of every dollar goes to organizations you’ve funded before.
$7.6M · 18 repeat orgs$2.1M to everyone else

18 repeat relationships — 9 still active in FY2024, 9 since wound down; 2 grantees were first funded in FY2024 (too recent to call).

How the two cohorts compare

Re-uppedFunded once

Organizations

18
17

Total granted

$7.6M
$1.9M

Median revenue growth · since first grant

+39%
+40%

Still filing today

50%
41%

New vs renewed · share of each year

In FY2024, 87% of grant dollars renewed an existing relationship; $221k went to new ones.

50%100%’17’18’19’20’21’22’23’24
RenewedFirst-time

Where new relationships form · theme of each grantee’s first grant

’17’18’19’20’21’22’23’24
EducationHealthOther

First-time = a grantee’s first year in your filing window; renewed = funded in an earlier year too. As a portfolio matures the renewed share naturally climbs — once funded, an org stays “renewable” — so the signal is the years that buck it (a new-grantee intake wave). The earliest year is left-censored: relationships that predate the data read as “new.” Theme is the grantee’s IRS cause.

Backed again, and grew

  • Vanderbilt University
    6× · 2017–2024 · $1.1M · revenue +74%
  • BC
    Baylor College of Medicine
    2× · 2019–2022 · $350k · revenue +47%
  • LU
    LOYOLA UNIVERSITY OF CHICAGO
    2× · 2021–2023 · $300k · revenue +30%

Funded once

  • UO
    University of Wisconsin
    one grant, 2022 · $300k
  • RU
    REGENTS UNIV OF CALIFORNIA
    one grant, 2021 · $150k
  • DUKE UNIVERSITYgraduated
    one grant, 2017 · $150k · revenue +51%

Repeat = funded in two or more distinct years; growth and survival are read from each grantee’s own subsequent IRS filings.

04Your field

The map has a center of gravity: the average direction from the rest of the sector toward the organizations the foundation funds — the shape of its giving. Scoring every nonprofit along that direction surfaces the ones that look most like the portfolio. These are the closest matchesthat aren’t grantees — a resemblance in what they say they do, not a recommendation.

1
New York University

Nyu is a private university with approximately 60,000 matriculating students in 20 schools and institutes. nyu's primary missions are education, research and scholarship, and patient care.

Education
2
Cornell University

Education, research, medical services and other public services.

Education
3
University of Southern California

The central mission of the university of southern california is the development of human beings and society as a whole through the cultivation and enrichment of the human mind and spirit. the principal means by which our mission is…

Education
4
University of Miami

See Form 990, Part I, Line 1, Description of Organization Mission.

Education
5
Lehigh University

The university's goal in the coming decade is to advance learning through the integration of teaching, research and service to others. the core of this goal is to prepare graduates to engage with the world and lead lives of meaning. to do…

Education
6
Seton Hall University

Seton hall university is a catholic institution of higher education

7
Drexel University

Drexel university fulfills its founder's vision of preparing each new generation of students for productive professional and civic lives while also focusing its collective expertise on solving society's greatest problems. drexel is an…

Education
8
Albany College of Pharmacy and Health Sciences

We educate the next generation of leaders to improve the health of our society.

Education
9
The Trustees of Princeton University

Research, education and general - princeton university is a private not-for-profit, non-sectarian institution of higher learning with approximately 5,700 undergraduate and 3,300 graduate students. 2,500 students graduated in the 2024-2025…

Education
10
Trustees of Boston University

Organization's mission: boston university is an international, comprehensive, private research university, committed to educating students to be reflective, resourceful individuals ready to live, adapt, and lead in an interconnected world.…

11
William Marsh Rice University

As a leading research university with a distinctive commitment to undergraduate education, Rice University aspires to path breaking research, unsurpassed teaching, and contributions to the betterment of our world. It seeks to fulfill this…

Education
12
Trustees of Dartmouth College

Dartmouth College educates the most promising students and prepares them for a lifetime of learning and of responsible leadership, through a faculty dedicated to teaching and the creation of knowledge.

Education

For reference, the grantee most central to the portfolio’s shape is Syracuse University and the most unlike its peers is Sanford Burnham Prebys Medical Discovery Institute. Resemblance is measured on each organization’s own IRS 990 mission text; it reflects how work is described, not its quality or impact.

Your grantees are a median of 80 years old; the field is 16. You back the established end — and your money leans older still.

THE FIELDby orgYOUR GRANTEESby number22%0%<5yr14%4%5–10yr19%8%10–20yr16%0%20–35yr13%17%35–55yr16%71%55yr+
THE FIELDby orgYOUR MONEYby value22%0%<5yr14%2%5–10yr19%24%10–20yr16%0%20–35yr13%13%35–55yr16%61%55yr+

The field is 22% startups (under 5 years old) — 0% of your grantees by number, and just 0% of your money.

Closures · last 5 years

The orgs you fund almost never close 5% lost their exemption, against 13% of the field you don’t fund.

orgs you fund
5%
2/39
the rest of the field
13%
240,394/1,819,526

Age = years since IRS exemption (a founding proxy). “Closed” = auto-revocation for 3 years of non-filing — a floor on closure, not proof, and bigger established orgs lapse least. Association, not causation.

04the grantee network

19 grantees tracked through their own filings, 2017–2025.

Each one resolved to its own IRS returns and tracked year by year — your grant beside their revenue from every source. Association, dated; never a causal claim.

Counted here: distinct organizations you funded across 20172025, not grant rows in a single year — so this will not match the grant count on the cover. 19 of the 39 grantees resolved in that span have returns of their own we could reconcile; the rest are funded organizations whose filings we could not track year by year.

0
Load-bearing (≥25% of a budget)
0
Early backer (in before they grew)
18/19
Grantees still filing
16/19
Grew since you first funded

Where your money sits — by cause, then by grantee

MASS GENERAL BRIGHAM INCORPORATED — $1,118,602 · OtherMASS GENERAL BRIGHAM INCORPORATEDPsychogenics Inc — $795,000 · OtherPsychogenics IncREGENTS OF THE UNIVERSITY OF COLORADO — $690,000 · OtherREGENTS OF THE UNIVERSITY OF COLORADOREGENTS OF THE UNIVERSITY OF CALIFORNIA AT SAN DIEGO — $450,000 · OtherREGENTS OF THE UNIVERSITY OF CALIFORNIA AT SAN DIEGOUniversity of Wisconsin Madison — $450,000 · OtherUniversity of Wisconsin MadisonREGENTS OF THE UNIVERSITY OF CALIFORNIA — $375,000 · OtherREGENTS OF THE UNIVERSITY OF CALIFORNIAUniversity of Wisconsin — $300,000 · OtherTHE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTE — $275,000 · OtherNorth Carolina State University — $270,982 · Other+14 more — $1,501,057 · Other+14 moreVanderbilt University — $1,129,211 · EducationVanderbilt UniversityBaylor College of Medicine — $350,000 · EducationBaylor College of MedicineLOYOLA UNIVERSITY OF CHICAGO — $300,000 · EducationLOYOLA UNIVERSITY OF CHICAGOTHE ROCKEFELLER UNIVERSITY — $240,000 · EducationTHE ROCKEFELLER UNIVERSITYDUKE UNIVERSITY — $150,000 · EducationDUKE UNIVERSITYICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — $149,996 · EducationICAHN SCHOOL OF MEDICINE AT MOU…SYRACUSE UNIVERSITY — $149,929 · EducationSYRACUSE UNIVERSITYYESHIVA UNIVERSITY — $149,912 · EducationYESHIVA UNIVERSITY+2 more — $121,200 · EducationChildren's Hospital Corporation — $300,000 · HealthChildren's…GREENWOOD GENETIC CENTER INC — $250,000 · HealthGREENWOOD …SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE — $150,000 · HealthSANFORD BU…WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH — $137,500 · HealthWHITEHEAD …CHILDREN'S HOSPITAL MEDICAL CENTER — $40,500 · HealthTHE CHILDREN'S HOSPITAL OF PHILADELPHIA — $40,100 · Health
Other$6,225,641Education$2,740,248Health$918,100

Each org by its size and your share of it — top-left is where you’re load-bearing

25%50%75%100%$10M$100Mgrantee revenue →↑ your share of their budgetVanderbilt University — $1,129,211 over 6y, 0.0% of budgetBaylor College of Medicine — $350,000 over 2y, 0.0% of budgetLOYOLA UNIVERSITY OF CHICAGO — $300,000 over 2y, 0.0% of budgetChildren's Hospital Corporation — $300,000 over 2y, 0.0% of budgetGREENWOOD GENETIC CENTER INC — $250,000 over 2y, 0.6% of budgetTHE ROCKEFELLER UNIVERSITY — $240,000 over 2y, 0.0% of budgetSANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE — $150,000 over 3y, 0.1% of budgetDUKE UNIVERSITY — $150,000 over 1y, 0.0% of budgetICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — $149,996 over 3y, 0.0% of budgetSYRACUSE UNIVERSITY — $149,929 over 1y, 0.0% of budgetYESHIVA UNIVERSITY — $149,912 over 1y, 0.1% of budgetUNIVERSITY OF SAN DIEGO — $142,406 over 1y, 0.0% of budgetWHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH — $137,500 over 3y, 0.1% of budgetMARYMOUNT UNIVERSITY — $75,000 over 1y, 0.1% of budgetTRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA — $75,000 over 1y, 0.0% of budgetEARLY SIGNAL FOUNDATION INC — $57,246 over 1y, 3.4% of budgetMassachusetts Institute of Technology — $46,200 over 1y, 0.0% of budgetCHILDREN'S HOSPITAL MEDICAL CENTER — $40,500 over 1y, 0.0% of budgetTHE CHILDREN'S HOSPITAL OF PHILADELPHIA — $40,100 over 1y, 0.0% of budget
Go grantee by grantee — a decade per org, and how each moved after you funded them

A decade per grantee — revenue shaded, your grants as bars, all rows on one timeline.

  • Who funds Vanderbilt University
  • Who funds Baylor College of Medicine
  • Who funds LOYOLA UNIVERSITY OF CHICAGO
  • Who funds Children's Hospital Corporation
  • Who funds GREENWOOD GENETIC CENTER INC
  • Who funds THE ROCKEFELLER UNIVERSITY
  • Who funds SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
  • Who funds DUKE UNIVERSITY
  • Who funds ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
  • Who funds SYRACUSE UNIVERSITY
  • Who funds YESHIVA UNIVERSITY
  • Who funds UNIVERSITY OF SAN DIEGO
  • Who funds WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
  • Who funds MARYMOUNT UNIVERSITY
  • Who funds TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
  • Who funds EARLY SIGNAL FOUNDATION INC
  • Who funds Massachusetts Institute of Technology
  • Who funds CHILDREN'S HOSPITAL MEDICAL CENTER
  • Who funds THE CHILDREN'S HOSPITAL OF PHILADELPHIA

The grantmakers whose grantees overlap with yours far more than size alone predicts. Each orbits closer the stronger the alignment; the arcs between them show where they also fund each other. Here it reads as a tightly interlocked camp — most of these funders back each other's grantees too.

Donor Advised Charitable Giving IncCA4.1× affinity4 shared granteesties to 1 of 1Hover any node to trace its alignments.Compare side by side →

Open a dossier: Donor Advised Charitable Giving Inc · Fidelity Investments Charitable Gift Fund

Affinity is a Gamma-Poisson posterior co-funding rate, re-centered on the typical rate, so thin evidence shrinks toward no signal. A research starting point: overlap is association, not proof of shared intent.

Government reliance of your grantees

Every dot is one organization International Rett Syndrome Foundation funds. Left–right is the share of its income from government; up–down is the share from you. Bigger dots raise more. Filter to federal or a single department — and drag the year to watch it move.

2024
202122232425
no gov · 00%0%1%3%5%your share of their income ↑0%19%38%56%75%share of the org’s income from governmentmedian 10%
  • Massachusetts Institute of Technology35% of income from government
  • Children's Hospital Corporation10% of income from government
  • Whitehead Institute for Biomedical Research7% of income from government
no gov moneyreceives it· size = income
0get no government money at all
0rely on government for over half their income
⤢ axis zoomed · 0–75%
typical government reliance, FY2025

Government income is each org’s traced federal awards (USASpending — grants and contracts) plus state payments (open checkbooks) as a share of its total revenue (IRS Form 990); the self-reported government-grant line (990 line 1e) is carried for cross-check: a grantee that reports government grants we could not trace to a source is left off the chart rather than shown as receiving none. An association, not a claim that your grant caused the public funding. Coverage is precision-first — a floor, not a census; state records exist for 9 states, so a grantee outside them shows no state figure (dimmed) rather than a false zero. Federal award amounts are obligations, which can span years, so a single-year share is indicative. 990 filings lag 12–24 months.

05Through Plinth

Warm introductions · Powered by PlinthPlus

How do I get to International Rett Syndrome Foundation?

Find your warmest path to International Rett Syndrome Foundation through trustees and officers whose names appear on both boards. Search for your organization and Plinth traces the shortest route it can evidence.

Each link is a name appearing on two organizations’ public IRS 990 filings, matched on that name and, where the filings support it, on location. A same-state match has geographic support, which is a second matching feature rather than confirmation that the two are one person; a cross-state one is the likeliest to be two people who share a name. Every hop shows its tier, low-confidence and distant paths are held back rather than guessed, and it is worth confirming the person before you use the introduction.

On method. Every financial figure here is read directly from IRS e-file XML — your own 990/990-PF and the multi-year returns of the 39 grantees we resolved across every year we hold, several hundred filings in all (a different count from the grant rows on the cover, which are one fiscal year)— each linked to its source. Grantee achievements and outcomes are each organization’s own program-service reporting (Form 990, Part III); we read these as association with sustained funding — the foundation is one of several forces — suppress low-confidence name matches rather than guess, and say so where a figure rests on a single grant or filing. Not everything on this page is a filed figure, and the difference matters. Filed is what you reported on your return. Official is another government record about an organization, such as a federal award or a charity register, joined by name where no shared identifier exists. Resolved is an identity we worked out where the filing named a recipient without an EIN, kept only above a measured confidence threshold. Computed is arithmetic over those, like themes, portfolio clusters and co-funder strength. Context is a statistic about a place rather than about an organization, which is what the need overlay is: it describes the area a grantee’s address sits in, not where its work lands. Inferred is drawn by a model from text, like the partnerships read out of public news and organization websites. Each is labeled where it appears. How we build these →

Generated from your IRS Form 990 e-file return for fiscal year 2024, released 2024. Filings run roughly 12–24 months behind; figures are dated accordingly.

Source object · view filing

More from the funding graph