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Illinois · Nonprofit

Provenance Precision Medicine Foundation

Provenance Precision Medicine Foundation (Illinois) receives grants from 4 organizations whose IRS filings report $159,250 to it, the largest being CLESS FAMILY FOUNDATION ($125,000). 1 of them have funded it in more than one year.

Revenue FY2025
$76k
Funders on record
4
Grants received
$159k
Net assets
$70k
1/4 repeat funders
01What it does

What Provenance Precision Medicine Foundation does

Mission

The Provenance Precision Medicine Foundation is committed to advancing access to innovative cancer treatments-particularly personalized cancer vaccines and other immunotherapies-for patients with advanced disease. Through direct patient support, education, and funding of clinical research, the foundation works to accelerate the availability of these therapies in the united states and help patients navigate options beyond the standard of care.

As stated on its FY2025 Form 990-EZ.

Programs

  1. Provided grants to support individuals with advanced cancer in accessing precision medicine, including genomic testing, personalized treatment recommendations, and innovative therapies such as individualized cancer vaccines. These grants enabled patients to pursue expert-recommended care not typically covered by insurance and supported early decision-making in treatment planning.

    $147,416 spentof which $147,416 as grants
    78% of program spending
  2. Engaged a consultant to initiate research and strategic planning to support access to cancer vaccine clinical trials in the United States. Two board members also traveled to Germany to meet with researchers and clinicians as part of this effort. These activities are part of the Foundation's ongoing work to expand the availability of innovative immunotherapies for patients with advanced cancer.

    $40,813 spent
    22% of program spending

The 2 programs described on its FY2025 Form 990-EZ. Program spending in total: $188,229.

02The organization over time

The organization over time

Each line starts at 100 in 2024, so what you read is the shape rather than the size: 150 means half as much again as 2024, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20242024 Revenue 100 ($281k) Expenses 100 ($101k) Net assets 100 ($202k)2025 Revenue 27 ($76k) Expenses 205 ($208k) Net assets 35 ($70k)
20242025
Revenue (27)Expenses (205)Net assets (35)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2024 to 2025, from $204k to $80k (−61%).

$204k
$80k
20242025
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2024
2025
ContributionsProgram revenueInvestmentOther

100% of Provenance Precision Medicine Foundation’s revenue is contributions — more reliant on donations than three-quarters of its peers (100% for the typical peer).

This organization
Typical peer · 12,248 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 1 of the last 2 reported years ran a deficit.

$180k
’24
−$132k
’25
24
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Chief executive

Dawn Brooke

Executive Director/Treasurer

Board chair

David Parker

Chair

As listed on its FY2025 Form 990-EZ.

03Who funds it

Who funds it, year by year

Grant support over time, funder by funder — shade shows the grant size each year.

2 of 4 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 15% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

From the IRS filings of Provenance Precision Medicine Foundation’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

Provenance Precision Medicine Foundation leans on a few funders — its largest provides 78% of grant income and the top three 94%; half comes from just 1 funder.

the vertical line marks half of all grant income — 1 funder to its left

78%
largest funder
94%
top three
~2
effective funders

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

Where its funders are

93% of Provenance Precision Medicine Foundation's grant income comes from Illinois funders.

IL
NY

Funder states come from each funder’s own filing. $24k arriving through sponsors registered in 2 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

Provenance Precision Medicine Foundation's revenue fell 73% between 2024 and 2025.

Operating margin−175% · bottom quartile
Revenue growth (annualized)−73% · bottom quartile

this organization peer median middle 50% of peers· 6,752 health nonprofits under $100k, FY2025

Organizations like Provenance Precision Medicine Foundation

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In Illinois

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Footprint & structure

Files a return copy in 1 state

IL

Screen this organization

A dated, signed PDF of the compliance screen for Provenance Precision Medicine Foundation: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds Provenance Precision Medicine Foundation?
Provenance Precision Medicine Foundation (Illinois) receives grants from 4 organizations whose IRS filings report $159,250 to it, the largest being CLESS FAMILY FOUNDATION ($125,000). 1 of them have funded it in more than one year.
How many funders does Provenance Precision Medicine Foundation have?
IRS filings report 4 organizations giving $159,250 in grants to Provenance Precision Medicine Foundation, 1 of which have funded it in more than one year.
Who is the largest funder of Provenance Precision Medicine Foundation?
CLESS FAMILY FOUNDATION is the largest funder on record, with $125,000 in grants. The full list of funders is on this page.
How can an organization like Provenance Precision Medicine Foundation find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in Illinois. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

Play a game about who funds Provenance Precision Medicine →

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2024–2025), and the filings of 4 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 22, 2026. What this page cannot tell you · view filing