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Massachusetts · Nonprofit

NUCLEATE BIO INC

NUCLEATE BIO INC (Massachusetts) receives grants from 9 organizations whose IRS filings report $567,500 to it, the largest being Mercatus Center Inc ($148,000). 4 of them have funded it in more than one year.

Revenue FY2025
$1.8M
Funders on record
9
Grants received
$568k
Net assets
$495k
4/9 repeat funderspeak grant-dependency 76%
01What it does

What Nucleate Bio Inc does

Mission

Empower tomorrow's biotech leaders by educating today's acedemic trainees

As stated on its FY2025 Form 990.

Program

  1. See schedule oactivator program - the goal of the nucleate "activator" program is to provide a rigorous and comprehensive educational experience to future biotech entrepreneurs. Our core curriculum consists of bi-weekly workshops held throughout the spring, and culminates in a final pitch event where teams showcase their companies to a large audience of industry stakeholders.the workshops, created in collaboration with our world-class advisors, are structured to address critical aspects of early-stage life science company formation. Together, they are designed to provide a roadmap for translating and commercializing early-stage technology concepts.each workshop consists of three parts:1) pre-work - teams prepare slides and discussion topics ahead of each workshop, which are circulated to workshop experts in advance. At the end of the program, these slides will form the building blocks of their final 10-15 minute polished pitch deck.2) hands-on feedback - during the 2-hour workshops, teams are paired with experts relevant to their targeted market and/or technology who provide feedback on the materials presented by the teams.3) post-work - after each workshop, teams integrate expert…

    $1,696,750 spentof which $66,770 as grants$13,590 earned by the program
    100% of program spending

The program described on its FY2025 Form 990. Program spending in total: $1,696,750.

02The organization over time

The organization over time

Each line starts at 100 in 2021, so what you read is the shape rather than the size: 150 means half as much again as 2021, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20212021 Revenue 100 ($132k) Expenses 100 ($28k) Net assets 100 ($103k)2022 Revenue 912 ($1.2M) Expenses 3451 ($983k) Net assets 311 ($320k)2023 Revenue 1957 ($2.6M) Expenses 8355 ($2.4M) Net assets 499 ($514k)2024 Revenue 1839 ($2.4M) Expenses 7742 ($2.2M) Net assets 706 ($728k)2025 Revenue 1338 ($1.8M) Expenses 6995 ($2.0M) Net assets 481 ($495k)
20212022202320242025
Revenue (1338)Expenses (6995)Net assets (481)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2021 to 2022, from $255k to $659k (+159%).

$255k
$659k
$744k
$1.0M
$772k
20212022202320242025
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2021
2022
2023
2024
2025
ContributionsProgram revenueInvestmentOther

99% of NUCLEATE BIO INC’s revenue is contributions — more reliant on donations than three-quarters of its peers (67% for the typical peer).

This organization
Typical peer · 498 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 1 of the last 5 reported years ran a deficit.

$103k
’21
$217k
’22
$194k
’23
$214k
’24
−$233k
’25
4.0
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

2022202320242025
Listed11151716
Joined·+5+4+1
No longer listed·122
03Who funds it

Who funds it, year by year

2021 → 2023: the base broadened from 1 funder to 6 funders, grant income rose $100k → $222k.

1 of 9 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 18% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

From the IRS filings of NUCLEATE BIO INC’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

NUCLEATE BIO INC leans on a few funders — its largest provides 26% of grant income and the top three 69%; half comes from just 2 funders.

the vertical line marks half of all grant income — 2 funders to its left

50% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund NUCLEATE BIO INC.

26%
largest funder
69%
top three
~5
effective funders

Largest funder’s share by year: 2021 100% · 2022 51% · 2023 45% — diversifying over time.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

Where its funders are

NUCLEATE BIO INC draws 94% of its grant income from funders outside Massachusetts, across 7 states in all.

WA
MA
CA
VA
DE
NC
TX

In-state vs out-of-state, by year

’21
’22
’23
Massachusetts out of state home

Funder states come from each funder’s own filing. $100k arriving through sponsors registered in 1 state is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

NUCLEATE BIO INC has grown faster than three-quarters of the 210 science & tech nonprofits its size.

Operating margin−13% · bottom quartile
Months of reserve4.0mo · below the median
Revenue growth (annualized)91% · top quartile

this organization peer median middle 50% of peers· 210 science & tech nonprofits $1M–$10M, FY2025

Organizations like NUCLEATE BIO INC

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In Massachusetts

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

85% of spending goes to programs.

Program 85%Management 15%Fundraising 0%

Governance

16
board members
100%
independent
✓Conflict-of-interest policy✓Whistleblower policy✓Document retention✓Board reviewed the 990✓Audited financials

Footprint & structure

Files a return copy in 1 state

MA

Screen this organization

A dated, signed PDF of the compliance screen for NUCLEATE BIO INC: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds NUCLEATE BIO INC?
NUCLEATE BIO INC (Massachusetts) receives grants from 9 organizations whose IRS filings report $567,500 to it, the largest being Mercatus Center Inc ($148,000). 4 of them have funded it in more than one year.
How many funders does NUCLEATE BIO INC have?
IRS filings report 9 organizations giving $567,500 in grants to NUCLEATE BIO INC, 4 of which have funded it in more than one year.
Who is the largest funder of NUCLEATE BIO INC?
Mercatus Center Inc is the largest funder on record, with $148,000 in grants. The full list of funders is on this page.
How can an organization like NUCLEATE BIO INC find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in Massachusetts. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2021–2025), and the filings of 9 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing