Colorado · Nonprofit
NORTH AMERICAN 3RS COLLABORATIVE INC
NORTH AMERICAN 3RS COLLABORATIVE INC (Colorado) receives grants from 1 organization whose IRS filings report $61 to it, the largest being AMAZONSMILE FOUNDATION ($61). 1 of them have funded it in more than one year, and 100% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
- Revenue FY2025
- $296k
- Funders on record
- 1
- Grants received
- $61
- Net assets
- $267k
What North American 3rs Collaborative Inc does
Mission
Advancing better science - for both people and animals - through facilitating education and collaborative expert working groups on animal welfare, study design, and non-animal methods.
As stated on its FY2025 Form 990.
Programs
General programs - the 3rs collaborative general programs advance the 3rs generally as a concept as well as specific 3rs topics. This includes working on advancing microphysiological systems, presentations on home cage monitoring, efforts related to refined mouse handling, and creating resources on environmental health monitoring. These efforts help scientists improve the lives of research animals, use fewer of them per experiment, and replace them altogether.
$27,650 spentof which $1,000 as grants$6,406 earned by the program19% of program spendingCompassion fatigue - the 3rs collaboratives compassion fatigue initiative works to improve the professional well-being of individuals working with research animals. In 2025 we launched a culture of care hub to support organizational culture. We also finalize work on our longitudinal manuscript on compassion fatigue.
$19,095 spent13% of program spendingCommunications/education/outreach - the 3rs communcation/education/outreach program maintained a free, open-access website with over 30 resource pages, sends regular newsletter educating stakeholders on resources/articles/webinars, and supports conference presentations. This program educates scientists, veterinarians, and animal care staff on methods to improve the lives of research animals, reduce the numbers necessary for research, and replace them with other technology.
$18,052 spent12% of program spendingOther programs - 3rs certificate, mps, tdb, development, rhm, and ai.
$81,443 spent$4,852 earned by the program56% of program spending
The 4 programs described on its FY2025 Form 990, listed largest first by expense. Program spending in total: $146,240.
The organization over time
Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.
Balance sheet
Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2024 to 2025, from $192k to $297k (+55%).
How it's funded, over time
Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.
95% of NORTH AMERICAN 3RS COLLABORATIVE INC’s revenue is contributions — more donation-reliant than the typical peer (86% for the typical peer).
Surplus & reserves
Operating surplus or deficit each year, and months of liquidity in hand. 1 of the last 7 reported years ran a deficit.
reserve
Leadership and staff
The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.
Chief executive
Megan La Follette
Executive director
As listed on its FY2025 Form 990.
Who funds it, year by year
2021 → 2023: the base held at 1 funder, grant income rose $17 → $28.
1 of 1 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 100% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.
From the IRS filings of NORTH AMERICAN 3RS COLLABORATIVE INC’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Where its funders are
100% of NORTH AMERICAN 3RS COLLABORATIVE INC's grant income arrives through donor-advised or pass-through sponsors, whose addresses record where the money is held rather than where the donor is. Too little is directly attributable to place on a map.
Funder states come from each funder’s own filing. $61 arriving through sponsors registered in 1 state is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.
Against its field
NORTH AMERICAN 3RS COLLABORATIVE INC runs a healthier operating margin than three-quarters of the 3,693 animals nonprofits its size.
this organization peer median middle 50% of peers· 3,693 animals nonprofits $100k–$1M, FY2025
Organizations like NORTH AMERICAN 3RS COLLABORATIVE INC
Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.
In Colorado
Nationally
Read directly from this organization’s own Form 990, as neutral context.
Where the money goes
70% of spending goes to programs.
Governance
Public support
74%
Share of support from the public (Schedule A) — the basis for its public-charity status.
Footprint & structure
Files a return copy in 2 states
Screen this organization
A dated, signed PDF of the compliance screen for NORTH AMERICAN 3RS COLLABORATIVE INC: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.
Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf
Questions and answers
- Who funds NORTH AMERICAN 3RS COLLABORATIVE INC?
- NORTH AMERICAN 3RS COLLABORATIVE INC (Colorado) receives grants from 1 organization whose IRS filings report $61 to it, the largest being AMAZONSMILE FOUNDATION ($61). 1 of them have funded it in more than one year, and 100% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
- How many funders does NORTH AMERICAN 3RS COLLABORATIVE INC have?
- IRS filings report 1 organization giving $61 in grants to NORTH AMERICAN 3RS COLLABORATIVE INC, 1 of which have funded it in more than one year.
- Who is the largest funder of NORTH AMERICAN 3RS COLLABORATIVE INC?
- AMAZONSMILE FOUNDATION is the largest funder on record, with $61 in grants. The full list of funders is on this page.
- How can an organization like NORTH AMERICAN 3RS COLLABORATIVE INC find more funders?
- Start with the funders already giving here, then look at the foundations that back similar organizations in Colorado. The funding by cause and by state pages list the largest funders for a given area and how to approach them.
Play a game about who funds North American 3rs Collaborative →
These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2025 (financials across 2017–2025), and the filings of 1 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing