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California · Nonprofit

CHAN ZUCKERBERG BIOHUB INC

CHAN ZUCKERBERG BIOHUB INC (California) receives grants from 3 organizations whose IRS filings report $22,607,866 to it, the largest being Silicon Valley Community Foundation ($12,597,866). 2 of them have funded it in more than one year, and 56% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.

Revenue FY2024
$100M
Funders on record
3
Grants received
$23M
Net assets
$1.4B
2/3 repeat funderspeak grant-dependency 63%
01What it does

What Chan Zuckerberg Biohub Inc does

Mission

Accelerating science through its mission to cure, prevent or manage all diseases by the end of the 21st century.

As stated on its FY2024 Form 990.

Program

On its FY2023 return the organization reported starting a significant new program.

The chan zuckerberg institute for advanced biological imaging aims to push forward the development and application of new imaging technologies over the next 10 to 15 years to obtain deep insights into the architecture of complex biological systems at the molecular level. The cz imaging institute will create breakthrough technologies hardware, software, biological probes, data, and platforms that will be made available to the scientific community and adopted worldwide through a combination of direct access to the institute, open sharing of advances, and commercial partnerships.

Its own explanation, from Schedule O of that return (Part III, line 2).

  1. In 2023 the chan zuckerberg biohub network (cz biohub network) continued to expand its work. In march 2023, czi announced the chan zuckerberg biohub chicago (cz biohub chicago) which catalyzes collaboration between the university of chicago, northwestern university, and the university of illinois urbana-champaign to develop new technologies for studying and measuring human biology that will use embedded sensors and probes to collect biological signals from human tissues with unprecedented resolution. Czi announced the chan zuckerberg biohub new york in october 2023, which brings together columbia university, the rockefeller university, and yale university to create new technologies to characterize and bioengineer immune cells with the ultimate goal of creating disease-specific "cellular endoscopes" that can detect early stages of disease in cells, monitor cell changes, and resolve diseases before they become untreatable. Also in 2023, cz biohub chicago held a launch event with representatives from the university of chicago, northwestern university, and the university of illinois urbana-champaign, as well as civic leaders. Towards cz biohub chicago's work to create new technologies…

    $87,510,653 spentof which $32,363,671 as grants$1,968,367 earned by the program
    100% of program spending

The program described on its FY2023 Form 990. Program spending in total: $87,510,653.

02The organization over time

The organization over time

Each line starts at 100 in 2017, so what you read is the shape rather than the size: 150 means half as much again as 2017, 50 means half. The number beside each label in the key is where it ended. The shaded band is where the middle 50% of its peers' revenue would sit, given their growth.

100 = 20172017 Revenue 100 ($9.5M) Expenses 100 ($34M) Net assets 100 ($553M)2018 Revenue 103 ($9.8M) Expenses 163 ($55M) Net assets 92 ($507M)2019 Revenue 129 ($12M) Expenses 193 ($65M) Net assets 82 ($454M)2020 Revenue 148 ($14M) Expenses 229 ($77M) Net assets 71 ($391M)2021 Revenue 109 ($10M) Expenses 218 ($74M) Net assets 59 ($327M)2022 Revenue 173 ($16M) Expenses 268 ($91M) Net assets 46 ($253M)2023 Revenue 13594 ($1.3B) Expenses 319 ($108M) Net assets 260 ($1.4B)2024 Revenue 1049 ($100M) Expenses 421 ($142M) Net assets 252 ($1.4B)
'17'18'19'20'21'22'23'24
Revenue (1049)Expenses (421)Net assets (252)Peer revenue range

Balance sheet

Total assets and total liabilities at each year end, in dollars. The largest one-year move in total assets was 2022 to 2023, from $271M to $1.5B (+446%).

$562M
$521M
$468M
$404M
$338M
$271M
$1.5B
$1.5B
'17'18'19'20'21'22'23'24
Total assetsTotal liabilities

How it's funded, over time

Each bar is one year's revenue split into where it came from, and every bar is the same height — these are shares, not amounts, so a year that raised twice as much looks the same size. Hover a bar for the split.

2017
2018
2019
2020
2021
2022
2023
2024
ContributionsProgram revenueInvestmentOther

Government-grant reliance: 2024 13%. Grants only. Government contracts and fees sit inside program revenue.

93% of CHAN ZUCKERBERG BIOHUB INC’s revenue is contributions — more reliant on donations than three-quarters of its peers (7% for the typical peer).

This organization
Typical peer · 4,743 orgs

Surplus & reserves

Operating surplus or deficit each year, and months of liquidity in hand. 7 of the last 8 reported years ran a deficit.

−$24M
’17
−$45M
’18
−$53M
’19
−$63M
’20
−$64M
’21
−$74M
’22
$1.2B
’23
−$43M
’24
12
months of
reserve

Leadership and staff

The officers, directors, trustees and key employees listed on each return. Joined and no longer listed compare each filing with the year before, matching people by surname and first initial; a year after a gap, or a roster under three people, has no comparison.

Chief executive

Matthias Haury

COO/acting executive director, czii

As listed on its FY2024 Form 990.

'17'18'19'20'21'22'23'24
Listed1617181820223022
Joined·+6+5+7+6+7+14+4
No longer listed·54745612
03Who funds it

Who funds it, year by year

2017 → 2022: the base broadened from 1 funder to 3 funders, grant income rose $2.0M → $6.5M.

2 of 3 of your funders are donor-advised or pass-through sponsors (tagged DAF) — 56% of grant dollars received. That money is really individual donors directing a sponsor; the institutions to cultivate are the non-DAF funders.

Left out of every figure on this page: $383M from one payer (the payer shares this organization's board, largest Chan Zuckerberg Initiative Foundation). These are real filings, and they are not money CHAN ZUCKERBERG BIOHUB INC raised.

From the IRS filings of CHAN ZUCKERBERG BIOHUB INC’s funders (the co-funder graph). Association, not causation. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

How concentrated its funding is

CHAN ZUCKERBERG BIOHUB INC leans on a few funders — its largest provides 56% of grant income and the top three 100%; half comes from just 1 funder.

the vertical line marks half of all grant income — 1 funder to its left

56% of the income these shares are computed over arrives through pass-through sponsors or from payers whose filings do not say what kind of payment it is. Concentration is still measured over all of it, because the money is real; what it does not support is a claim about how many institutions have chosen to fund CHAN ZUCKERBERG BIOHUB INC.

56%
largest funder
100%
top three
~2
effective funders

Largest funder’s share by year: 2017 100% · 2019 100% · 2020 78% · 2021 62% · 2022 69% — diversifying over time.

“Effective funders” = inverse Herfindahl index (1 / Σ shareᵢ²) — the number of equal-sized funders that would give the same concentration. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

Where its funders are

56% of CHAN ZUCKERBERG BIOHUB INC's grant income arrives through donor-advised or pass-through sponsors, whose addresses record where the money is held rather than where the donor is. Of the $10M that is directly attributable, 100% of it comes from California funders.

CA

In-state vs out-of-state, by year

’17
’19
’20
’21
’22
California out of state home

Funder states come from each funder’s own filing. $13M arriving through sponsors registered in 2 states is excluded from the map and the split above: a sponsor holds money on a donor’s behalf, so its registered address would place those dollars somewhere no donor need ever have been. Trends are read to FY2023, the last fiscal year that has finished arriving. FY2024–FY2026 are still being filed and are shown unshaded; they do not move any figure on this page.

04Its place in the field

Against its field

CHAN ZUCKERBERG BIOHUB INC holds deeper cash reserves than three-quarters of the 4,580 health nonprofits its size.

Operating margin−43% · bottom quartile
Months of reserve12.4mo · top quartile
Revenue growth (annualized)40% · top quartile

this organization peer median middle 50% of peers· 4,580 health nonprofits $10M–$100M, FY2024

Organizations like CHAN ZUCKERBERG BIOHUB INC

Organizations whose mission and program text most resemble this one, by semantic similarity over every organization in the US filings — the closest peers, and often the clearest route to shared or prospective funders.

In California

Nationally

05Profile & governance

Read directly from this organization’s own Form 990, as neutral context.

Where the money goes

85% of spending goes to programs.

Program 85%Management 15%Fundraising 0%

Governance

10
board members
60%
independent
✓Conflict-of-interest policy✓Whistleblower policy✓Document retention✓Board reviewed the 990✓Audited financials

Footprint & structure

Files a return copy in 4 states

IL
NY
OR
CA

Part of a family of 13 related entities

  • Chan Zuckerberg Institute for Advanced Biological Imaging LLC · disregarded
  • Cz Biohub Chicago LLC · disregarded
  • Cz Biohub New York LLC · disregarded
  • Cz Biohub Sf LLC · disregarded
  • Chan Zuckerberg Initiative Advocacy · exempt

Screen this organization

A dated, signed PDF of the compliance screen for CHAN ZUCKERBERG BIOHUB INC: IRS status (Business Master File, Publication 78, auto-revocation), the OFAC sanctions lists, the Internal Revenue Bulletin, and California registration, with the Rev. Proc. 2018-32 §8.01 reliance elements stated element by element. Generated from the current files at the moment you download it.

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Screens are triage, not determinations; a source that cannot be read reports not screened, never clear. Screen this nonprofit · How the screen works · on the API as GET /api/screening/{ein}?format=pdf

Questions and answers

Who funds CHAN ZUCKERBERG BIOHUB INC?
CHAN ZUCKERBERG BIOHUB INC (California) receives grants from 3 organizations whose IRS filings report $22,607,866 to it, the largest being Silicon Valley Community Foundation ($12,597,866). 2 of them have funded it in more than one year, and 56% of the money arrives through donor-advised or pass-through sponsors rather than from an institution directly.
How many funders does CHAN ZUCKERBERG BIOHUB INC have?
IRS filings report 3 organizations giving $22,607,866 in grants to CHAN ZUCKERBERG BIOHUB INC, 2 of which have funded it in more than one year.
Who is the largest funder of CHAN ZUCKERBERG BIOHUB INC?
Silicon Valley Community Foundation is the largest funder on record, with $12,597,866 in grants. The full list of funders is on this page.
How can an organization like CHAN ZUCKERBERG BIOHUB INC find more funders?
Start with the funders already giving here, then look at the foundations that back similar organizations in California. The funding by cause and by state pages list the largest funders for a given area and how to approach them.

These figures are read directly from IRS Form 990 / 990-PF e-file XML: this organization’s own return for FY2024 (financials across 2017–2024), and the filings of 3 funders that report grants to it. “On record” means captured in the filings we have parsed — a funder that does not e-file, or whose grant detail is not itemized, will not appear. Filings run roughly 12–24 months behind. Trends on this page end at FY2023, the last fiscal year that has finished arriving; later years are shown and marked, and move no figure. Data on this page was exported October 14, 2026. What this page cannot tell you · view filing